Analysis of Forced Expiratory Flow Signals Using the New Luus-Jaakola Optimization Procedure.

Objective: The aim of this study was to estimate forced vital capacity (FVC) by analyzing incomplete forced expiratory flow-time (FEFT) curves using the new Luus-Jaakola (NLJ) optimization procedure.

Methods: Complete FEFT curves from 90 subjects with and without respiratory disease were used to validate the method, and its application performance was evaluated by FEFT curves containing incomplete curves from nine obstructive patients. First, a lumped parameter model of the FEFT curve, taking FVC as one of the model parameters, is chosen.