New prenyl flavanone and diarylbutanol from stem bark and their -glucosidase inhibitory activity.

One new prenyl flavanone (), (2)-8-prenyl-5,6-dihydroxy-7-methoxyflavanone, and one new diarylbutanol (), (7')-3'-hydroxy-linderagatin-A, were isolated from the stem bark of (Annonaceae), along with five known compounds, eriodictyol (), quercetin (), paprazine (), --caffeoyltyramine (), and --feruloyltyramine (). Their structures were determined through extensive spectroscopic analyses and comparison with the literature. The -glucosidase inhibitory potential of was evaluated.

Two new dimethylpyranoflavanones from the roots of .

Two previously unreported dimethylpyranoflavanones, pyronomelodorones A and B ( and ), along with five known compounds, 7--methyldihydrowogonin (), 5,6,7-trimethoxyflavanone (), 5,6-dihydroxy-7-methoxy-dihydroflavone (), 5,7,8-trimethoxydihydroflavone (), and pinostrobin (), were isolated from the roots of The structures of all isolates were fully characterized using spectroscopic data and comparison with the previous literature. All isolates were evaluated for their -glucosidase inhibition and their cytotoxicity against KB, HepG2, and MCF7 cell lines. Among the isolates, compound exhibited the most inhibitory activity against -glucosidase and was superior to the positive control with an IC value of 1.

A new triterpenoid saponin from .

From the ethanol extract of , collected at Phu Yen province, Viet Nam, one new triterpenoid saponin () and four known compounds () were isolated. By means of NMR and HR-ESI-MS analyses, their structure was elucidated as 3--(β-D-xylopyranosyl-(1→3)-β-D-xylopyranosyl)spergulagenin A or glinusopposide V (), glinusopposide L (), spergulin B (), vitexin () and astralagin (). Two compounds () showed weak inhibitory activity against .