The genus Gnetum: Traditional use, phytochemistry, nutritional value, biosynthesis, synthesis, pharmacology, toxicology, synthetic advance, and pharmacokinetics.

Background: Gnetum is the sole genus within the family Gnetaceae. Numerous species are edible, their seeds can be roasted, and the leaves can be consumed as vegetables. Gnetum plants have been highly esteemed in traditional folk medicine worldwide for many years.