Efficacy of Huaiqihuang granules as adjuvant therapy for bronchial asthma in children: a real-world study.

Objectives: To study the efficacy of Huaiqihuang granules as adjuvant therapy for bronchial asthma in children.

Methods: A multicenter, prospective, and registered real-world study was performed for the children, aged 2-5 years, who had a confirmed diagnosis of bronchial asthma in the outpatient service of 21 hospitals in China. Among these children, the children treated with medications for long-term asthma control (inhaled corticosteroid and/or leukotriene receptor antagonist) without Huaiqihuang granules were enrolled as the control treatment group, and those treated with medications for long-term asthma control combined with Huaiqihuang granules were enrolled as the combined treatment group.

[Correlations of IL-4R gene polymorphism and serum IgE levels with asthma predictive index].

Objective: To study the correlations of IL-4R gene polymorphism and serum IgE levels with asthma predictive index (API) in children.

Methods: One hundred and sixty-seven children with positive API, 187 children with negative API and 203 healthy children (control group) were enrolled. PCR and DNA sequencing were used to identify genotypes of the Arg551Gln locus in IL-4R gene.

[Correlation between insulin resistance and myocardial injury in critically ill children].

Objective: To study the relationship between insulin resistance and myocardial injury in children with critical diseases in light of the fact that such children usually suffer from noticeable insulin resistance and myocardial injury.

Methods: Sixty-three children with critical diseases who were admitted between March 2010 and June 2011 were enrolled to comprise a case group. Fasting blood glucose, serum insulin, myocardial enzyme, and troponin I (CTnI) levels were measured.

[Efficacy of sublingual immunotherapy in children with dust mite allergic asthma].

Objective: To compare the efficacy of sublingual immunotherapy (SLIT) combined with inhaled corticosteroids (ICS) versus ICS alone in children with mild and moderate dust mite allergic asthma.

Methods: Thirty-two children with mild and moderate dust mite allergic asthma were randomly divided into two groups: SLIT+ICS (n=18) and ICS alone (n=14). A total of 30 children completed the one year clinical observation .

[Risk factors for simple obesity in preschool children from four kindergartens of Urumqi City].

Objective: To investigate the incidence of simple obesity and risk factors for the development of this disorder in preschool children from Urumqi City.

Methods: A total of 1730 children at ages of 3-7 years sampled randomly from four district kindergartens of Urumqi City were enrolled in this study. Their heights and weights were measured.

[Sleep disorders and their influencing factors in primary school children from Urumqi].

Objective: To understand the prevalence of sleep disorders and their influencing factors in primary school children from Urumqi.

Methods: A total of 2034 children at the ages of 6-14 years were randomly sampled in 3 districts of Urumqi. The children's sleep states and their family and social environments were investigated through questionnaires.

[Detection of peak expiratory flow in healthy children in Xinjiang].

Objective: To establish reference values of peak expiratory flow (PEF) for children in Xinjiang.

Methods: A total of 3520 healthy children (1705 males and 1815 females) aged from 7 to 16 years were enrolled in this study. PEF was measured using MicroPeak Peak Flow Meter.