Publications by authors named "Duoduo Gu"

Epithelioid hemangioma (EHE) is a rarely malignant tumor originating from the vascular endothelium. Morphological manifestations and immunohistochemical staining results are key to diagnosing EHE. Herein, we present a case of cutaneous involment in a recurrence of EHE.

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Article Synopsis
  • - Melasma is a chronic skin condition that causes increased pigmentation and affects many people worldwide, but its exact causes are not fully understood.
  • - Key skin changes involved in melasma include issues with the skin barrier, damage to the basement membrane, and various changes in the dermis like aging cells and blood vessel alterations.
  • - The article also discusses possible treatments and highlights the need for further research into the role of systemic factors, such as hormones and oxidative stress, in melasma development.
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Article Synopsis
  • Rosacea is a chronic skin condition that affects the midface, causing redness, flushing, and other symptoms that impact appearance and quality of life.
  • Tranexamic acid (TA) is a synthetic compound traditionally used to treat bleeding, and it is being researched for its potential in managing skin conditions, including rosacea.
  • This study compiles existing literature on TA's effectiveness for rosacea and highlights methods such as oral, topical, and injection-based treatments, showing that TA may help improve symptoms by enhancing skin barrier function, reducing immune responses, and limiting blood vessel formation.
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Computer-assisted full facial imaging systems are currently among the most widely used skin analysis instruments in dermatology and medical cosmetology. These systems offer objective quantitative evaluation of facial skin conditions, and as they are non-invasive, play an important role in assessing dermatological conditions such as pigmentation, inflammation, vascular diseases, skin texture, the severity of ageing, and therapeutic follow-up. Although computer-assisted full facial imaging systems enable quantitative analysis in the scope of medical treatment and cosmetic evaluation, their results may considerably vary because of the influence of environmental and postural factors for improper operation.

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Background: During the coronavirus disease 2019 pandemic, wearing medical respirators and masks was essential to prevent transmission.

Objective: To quantify the effects of N95 mask usage by measuring facial skin biophysical characteristics and changes in the lipidome.

Methods: Sixty healthy volunteers wore N95 respirators for 3 or 6 h.

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Background And Aim: Clinical manifestations of rosacea include transient or persistent facial erythema, telangiectasia, papules, and pustules. The existing assessment tools primarily evaluate the facial area to assess the severity of rosacea. However, in addition to the face, telangiectasia, erythema, and flushing can occur in the ear.

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Morbihan disease is a rare entity involving the upper two-thirds of the face and characterized by chronic erythematous edema, which is recalcitrant to the traditional therapy of rosacea. We report a case of Morbihan disease effectively treated with macro-focused high-intensity focus ultrasound (MF-HIFU). After MF-HIFU treatment, an obvious reduction in swelling was observed with decreased erythema and hyperalgesia.

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Individuals with rosacea have different facial erythema distribution patterns; however, whether they are related to the skin type is unclear. This study enrolled 201 Chinese patients, including 195 females and six males, diagnosed with rosacea. Facial images were taken using the VISIA® Complexion Analysis System, and red-area images were further analyzed.

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