Publications by authors named "Dunia Marrero-Arencibia"
Article Synopsis
- Some epidemiological data indicate a potential link between cholesterol levels and thyroid cancer risk, prompting this study to assess lipid profiles in patients with Bethesda category IV thyroid nodules.
- The study involved 204 patients who underwent thyroid surgery and had prior lipid profile testing, comparing those diagnosed with cancer against those with benign conditions.
- Results showed that patients with thyroid cancer had significantly lower total cholesterol, LDL, and non-HDL cholesterol levels, with LDL being the only lipid measure independently associated with malignancy; follicular carcinoma patients had the lowest cholesterol levels.
Purpose: It has been suggested that increasing levothyroxine dose to lower TSH levels within the normal laboratory range might be a therapeutic option for patients with apparently well-controlled primary hypothyroidism who are dissatisfied with their treatment and complain of physical or psychological symptoms. This study assessed whether there is a relationship between TSH levels and health-related quality of life (HRQoL) among subjects with adequately treated hypothyroidism.
Methods: HRQoL was measured with the specific thyroid disease ThyPRO-39 questionnaire in 218 consecutive patients with primary hypothyroidism of any cause attending an Endocrinology Department in a single center.
Fine needle aspiration biopsy does not permit to distinguish between benign and malignant follicular thyroid lesions (category IV in the Bethesda Cytopathology System). Some reports have suggested an association between increased serum TSH levels and thyroid cancer, so the aim of this study was to investigate the association between TSH levels and malignancy in patients with follicular thyroid nodules. Therefore, we conducted a retrospective study of all subjects who underwent surgical treatment for Bethesda IV thyroid nodules in a single center (years 2012-2017).
View Article and Find Full Text PDFAdaptation and cross-cultural validation of the Spanish version of the Thyroid-Related Quality-of-Life Patient-Reported Outcome questionnaire.
Endocrinol Diabetes Nutr (Engl Ed)
November 2018
Introduction: The ThyPRO questionnaire is the most widely used tool for measuring quality of life in patients with benign thyroid diseases. The purpose of this study was to adapt and validate a Spanish translation of the ThyPRO and its abbreviated version (ThyPRO-39).
Material And Methods: Adaptation to the Spanish language was performed using the forward-backward translation method, followed by a pretesting study on five representative patients.