Publications by authors named "Dunhong Wei"

Background: This study aimed to establish a traumatic hemorrhagic shock (THS) model in swine and examine pathophysiological characteristics in a dry-heat environment.

Methods: Forty domestic Landrace piglets were randomly assigned to four study groups: normal temperature non-shock (NS), normal temperature THS (NTHS), desert dry-heat non-shock (DS), and desert dry-hot THS (DTHS) groups. The groups were exposed to either normal temperature (25°C) or dry heat (40.

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Motor imagery provides direct insight into an anatomically interconnected system involved in the integration of sensory information with motor actions, a process that is associated with positive symptoms in schizophrenia (SCZ). However, very little is known about the electrophysiological processing of motor imagery in first episode SCZ. In the current study, we used a visual hand mental rotation (MR) paradigm to manipulate the processing of motor imagery while event-related brain potentials (ERPs) were recorded in 42 SCZ participants and 40 healthy controls (HC).

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Background: Mismatch negativity (MMN) and P3a components are sequential and co-occur. MMN represents the pre-attentive index of deviance detection and P3a represents the attention orienting response. Major depressive disorder (MDD) is characterized by impaired pre-attentive information processing.

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Article Synopsis
  • The study links the number of depressive episodes to how patients process emotional facial expressions, particularly showing that those with recurrent major depression (R-MD) struggle more with happy and neutral faces but react differently to sad faces compared to healthy controls.
  • F-MD patients exhibit longer reaction times (latencies) and lower brain activity (N170 amplitudes) when recognizing various emotions, indicating a significant impairment in processing emotional cues.
  • The findings suggest that increased depressive episodes exacerbate these emotional processing issues, highlighting the need for understanding these abnormalities in treating depression.
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Background: Mental rotation performance may be used as an index of mental slowing or bradyphrenia, and may reflect, in particular, speed of motor preparation. Previous studies suggest depressive patients present the correlates of impaired behavioural performance for mental rotation and psychomotor disturbance. The aim of this study is to compare the mental rotation abilities of patients with a first episode of depression, recurrent depression and healthy control subjects with regard to hand tasks.

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Mental rotation (MR) performance provides a direct insight into a prototypical higher-level visuo-spatial cognitive operation. Previous studies suggest that progressive slowing with an increasing angle of orientation indicates a specific wing of object-based mental transformations in the psychomotor retardation that occurs in major depressive disorder (MDD). It is still not known, however, whether the ability of object-rotation is associated with the ability of ego-rotation in MDD.

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