Fabrication and evaluation of BerNPs regarding the growth and development of .

In this study, berberine nanoparticles (BerNPs) were prepared using a wet-milling method with zirconium balls to enhance bioavailability and expand potential applications. The particle size and physicochemical properties of the BerNPs were analyzed using field-emission scanning electron microscopy (FE-SEM), UV-vis spectroscopy, X-ray diffraction, and Fourier-transform infrared spectroscopy. The broth dilution method was used to determine the antimicrobial activity of the BerNPs against ().

Predictive validity of the sequential organ failure assessment score for mortality in patients with acute respiratory distress syndrome in Vietnam.

Evaluating the prognosis of ARDS patients using grading systems can enhance treatment decisions. This retrospective observational study evaluated the predictive accuracy of the SOFA score, APACHE II score, SpO/FiO ratio, and PaO/FiO ratio for mortality in ARDS patients in Vietnam. The study included 335 adult ARDS patients admitted to a central hospital from August 2015 to August 2023.

Polypropylene Mesh in Nipple-Sparing Mastectomy and Immediate Implant-based Breast Reconstruction in Vietnamese Early Breast Cancer Patients: Safe and Feasible.

Background: Breast cancer is the most common malignancy in women worldwide, and breast reconstruction following mastectomy is an integral part of patient care to improve quality of life and aesthetic outcomes. Nipple-sparing mastectomy (NSM) combined with immediate breast reconstruction (IBR) with implant is becoming increasingly preferred due to its ability to preserve breast aesthetics. Acellular dermal matrix (ADM) is commonly used in these procedures, but is often prohibitively expensive, particularly in resource-limited settings like Vietnam.

Urological Applications of Novel Hyaluronic Acid/Alginate Gel to Protect Nerves: A Single-Surgeon Experience.

Background Tissue gliding and mobility are crucial for the success of penile procedures, as postoperative adhesions can lead to painful tethering of tissues, including nerves. While most commercially available options are not designed to reduce friction and/or often have inconsistent bioresorption, a novel hyaluronic acid/alginate hydrogel represents a significant advancement in reducing postoperative tissue adhesions. This study aimed to evaluate its intra-operative application in pediatric and adult urologic surgeries with associated indications and postoperative outcomes (re-admission, re-operation, complications).

Reconstruction of Complex Nasal Defect With Anterolateral Thigh Chimeric Flap.

Total nasal defects, including adjacent soft tissue damage, present a challenge for plastic surgeons, and in this case, free flaps should be an alternative when local flaps are limited. However, the importance of donor site morbidity must be taken into account for free flaps. Due to flap bulkiness, the anterolateral thigh (ALT) free flaps are less commonly used to restore nasal structures.

Knowledge and attitudes about dementia among nursing students in Vietnam: a cross-sectional study.

Background: Dementia is one of the most pressing health concerns among the ageing population, imposing significant health, financial and caregiving burdens on people with dementia (PWD), their families and caregivers. Building the capacity of nursing students is essential for effectively improving quality of life for affected people. This study aimed to assess nursing students' knowledge and attitudes toward dementia and its associated factors.

Mindfulness Practice and Work Performance: The Mediating Role of Emotional Intelligence and Psychological Capital.

Purpose: The practice of mindfulness is becoming more widespread among employees, with potential benefits for workplace outcomes. However, there is a paucity of research on the mechanisms linking mindfulness to job performance.

Method: This study investigated the mediating functions of emotional intelligence and psychological capital in the relationship between mindfulness and job performance among 263 office employees in Ho Chi Minh City, Vietnam.

Contamination of retail market meat with extended-spectrum beta-lactamase genes in Vietnam.

The contamination of retail meat with antibiotic-resistant bacteria poses a substantial public health risk because of the potential spread of these bacteria within communities. The contamination of retail meat with extended-spectrum beta-lactamase (ESBL)-producing bacteria was investigated in four cities in Vietnam using real-time PCR, employing ESBL marker genes. This method provides a more comprehensive assessment of ESBL-producing bacterial contamination in meat samples than culture-based methods because it directly detects resistance genes from the extracted sample DNA.

A rare case of acute respiratory distress syndrome due to chlorine gas inhalation: Rapid progression with favorable ICU outcome.

Acute respiratory distress syndrome (ARDS) secondary to chlorine gas inhalation is a rare yet critical condition that can lead to severe respiratory failure if not managed promptly. This case report presents a 43-year-old male who developed ARDS after accidental exposure to chlorine gas during pool maintenance. The patient's condition deteriorated rapidly, with symptoms progressing to acute pulmonary edema and severe hypoxemia, requiring immediate transfer to the intensive care unit (ICU).

Glaucoma Clinic Monitoring Over 6 Months Using Online Circular Contrast Perimetry in Comparison with Standard Automatic Perimetry: The Developing-World Setting.

Purpose: Online circular contrast perimetry provides visual field testing on any computer or tablet without additional hardware. This study compared outcomes of online circular contrast perimetry (OCCP) and standard automated perimetry (SAP) in a developing world setting.

Methods: The longitudinal and observation study was conducted on patients sampled during 2023 at Hanoi Medical University Hospital.

A Novel Urological Application of Hyaluronic Acid/Alginate Sheet to Prevent Adhesion Formation: A Technique Guide and Case Series.

Tissue gliding and mobility are paramount to the success of penile procedures. While postoperative healing is intended to protect, repair, and nourish injured tissues, an overzealous response often leaves painful and debilitating tethering between the corpora, including nerves, and surrounding tissues. This tethering interferes with the intended outcomes of surgery by preventing necessary gliding.

Predictive validity of interleukin 6 (IL-6) for the mortality in critically ill COVID-19 patients with the B.1.617.2 (Delta) variant in Vietnam: a single-centre, cross-sectional study.

Objectives: To investigate the serum IL-6 levels and their rate of change in predicting the mortality of critically ill patients with COVID-19 in Vietnam.

Design: A single-centre, cross-sectional study.

Setting: An Intensive Care Centre for the Treatment of Critically Ill Patients with COVID-19 in Ho Chi Minh City, Vietnam.

Trends in head and neck cancer incidence in Ho Chi Minh City, Vietnam between 1996 and 2015.

Introduction: This study provides an analysis of head and neck cancer (HNC) cases over a 20-year period in Ho Chi Minh City, Vietnam. It aims to shed light on HNC's characteristics and trends in this highly populated urban region.

Methods: The analysis encompasses 8974 HNC cases, emphasising incidence rates, gender distribution, and the prevalence of different subtypes, including oral cavity, nasopharyngeal, oropharyngeal, and laryngeal/pharyngeal cancers.

Reconstructing suspended sediment concentrations in the Mekong River Basin via semi-supervised-based deep neural networks.

The Mekong River Basin (MRB) is crucial for the livelihoods of over 60 million people across six Southeast Asian countries. Understanding long-term sediment changes is crucial for management and contingency plans, but the sediment concentration data in the MRB are extremely sporadic, making analysis challenging. This study focuses on reconstructing long-term suspended sediment concentration (SSC) data using a novel semi-supervised machine learning (ML) model.

Facial reconstruction with thinned anterolateral thigh free flap.

Facial reconstruction is challenging for plastic surgeons, as it can be difficult to decide the best approach. One technique that has been widely used is the anterolateral thigh (ALT) flap due to its numerous benefits. However, its thickness can be a drawback, especially regarding facial reconstruction.

Bacteroides ovatus alleviates dysbiotic microbiota-induced graft-versus-host disease.

Acute lower gastrointestinal GVHD (aLGI-GVHD) is a serious complication of allogeneic hematopoietic stem cell transplantation. Although the intestinal microbiota is associated with the incidence of aLGI-GVHD, how the intestinal microbiota impacts treatment responses in aLGI-GVHD has not been thoroughly studied. In a cohort of patients with aLGI-GVHD (n = 37), we found that non-response to standard therapy with corticosteroids was associated with prior treatment with carbapenem antibiotics and a disrupted fecal microbiome characterized by reduced abundances of Bacteroides ovatus.

The First-In-Class Deubiquitinase-Targeting Chimera Stabilizes and Activates cGAS.

Deubiquitinase-targeting chimera (DUBTAC) is a promising technology for inducing targeted protein stabilization (TPS). Despite its therapeutic potential, very few proteins have been stabilized by DUBTACs to date. The limited applicability of this technology is likely due to the modest DUBTAC-induced protein stabilization effect, and the scarcity of effective deubiquitinase ligands that can be harnessed for DUBTAC development.

Reconstructive management of a patient with Tessier number 10 cleft.

Tessier number 10 cleft is one of the rarest facial clefts. Surgical treatment of this type of cleft is challenging due to the complexity of periorbital and temporal soft tissue deformities. A 23-year-old male patient presented with typical facial deformities of Tessier number 10 cleft.

Knowledge and attitudes about dementia among nursing students in Vietnam: a cross sectional study.

Introduction: Dementia is one of the most pressing health concerns in ageing population, posing significant burdens not only on the well-being and independence of people with dementia (PWD), but also on their families and communities. Building capacity for nursing students is essential for effectively enhancing the quality of life for affected people. However, various studies have highlighted knowledge gaps concerning dementia among nursing students worldwide.

Comparative resistomics analysis of multidrug-resistant Chryseobacteria.

Chryseobacteria consists of important human pathogens that can cause a myriad of nosocomial infections. We isolated four multidrug-resistant Chryseobacterium bacteria from activated sludge collected at domestic wastewater treatment facilities in the New York Metropolitan area. Their genomes were sequenced with Nanopore technology and used for a comprehensive resistomics comparison with 211 Chryseobacterium genomes available in the public databases.

Abundance of Colistin-Resistance Genes in Retail Meats in Vietnam.

The degree of contamination of retail meat with colistin-resistant bacteria and its potential contribution to dissemination within communities remains to be determined. Thus, we aimed to elucidate the contamination status of colistin-resistance genes, indicative of colistin-resistant bacteria, in retail meats in Vietnam. In total, 46 chicken and 49 pork meats from stores in Vietnam and Japan were examined.

Stakeholder perspectives following implementation of Vietnam's first speech-language pathology degrees: recommendations for future curriculum development.

Purpose: To investigate perspectives of multiple stakeholders involved in development and delivery of Vietnam's first speech-language pathology degrees and derive recommendations for future degrees in Vietnam and other Majority World countries.

Methods: An exploratory-descriptive qualitative research design using focus groups and individual semi-structured interviews in the preferred language (English or Vietnamese) was used, with 70 participants from five stakeholder groups: project managers, students, academic educators, placement supervisors and interpreters. Transcriptions were analysed using thematic network analysis.

Simple and Rapid Method of Microwell Array Fabrication for Drug Testing on 3D Cancer Spheroids.

Three-dimensional (3D) cell culture systems are becoming increasingly popular due to their ability to mimic the complex process of angiogenesis in cancer, providing more accurate and physiologically relevant data than traditional two-dimensional (2D) cell culture systems. Microwell systems are particularly useful in this context as they provide a microenvironment that more closely resembles the in vivo environment than traditional microwells. Poly(ethylene glycol) (PEG) microwells are particularly advantageous due to their bio-inertness and the ability to tailor their material characteristics depending on the PEG molecular weight.