Publications by authors named "Dung N"

In this study, we report the successful fabrication of a novel antibacterial triboelectric nanogenerator (TENG) using a polymer composite film based on polyhexamethylene guanidine hydrochloride (PHMG). The composite materials, with optimised ingredient ratios, consist of PHMG, polyvinyl alcohol (PVA) and glutaraldehyde (GA) as a crosslinking agent (PHMG-GA-PVA). Utilising 3D printing, these composite materials were directly deposited on the conductive substrates and used as positive TENG electrodes.

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(1) Background: Asthma exacerbations represent significant clinical events, however, the underlying inflammatory mechanisms and cytokine profiles in patients with frequent exacerbations remain incompletely understood; (2) Methods: In this prospective, cross-sectional study of 120 stable asthma patients, we compared the serum concentrations of eight key cytokines (IL-4, IL-12, IL-13, IL-17, IFN-α, IFN-γ, TNF-α, and IL-1β) between two groups: 60 patients with frequent exacerbations (≥ 2 events per year) and 60 matched controls with few exacerbations (1 event per year); (3) Results: Patients with frequent exacerbations showed significantly higher serum concentrations of IL-4 and IL-13 ( < 0.05), along with an increased prevalence of allergic history and comorbidities (chronic rhinosinusitis, GERD, OSA; all < 0.05).

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This study analyzed the nutritional composition, bioactive compounds, antioxidant activities and estimated potential renal acid load (PRAL) score of orange-fleshed sweet potato (OFSP) grown in Vietnam. In addition, important functional groups of carotenoid compounds in OFSP were identified by Fourier transform infrared spectroscopy (FTIR); carotenoid pigments were detected and quantified by high-performance liquid chromatography (HPLC). The results showed that, OFSP had outstanding physicochemical characteristics, containing many nutrients, bioactive substances, minerals and fiber.

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Background: Awake prone positioning (APP) may be beneficial in patients with respiratory failure who are not receiving mechanical ventilation. Randomized controlled trials of APP have been performed during peak COVID-19 periods in unvaccinated populations, with limited data on compliance or patient acceptability. We aimed to evaluate the efficacy and acceptability of APP in a lower-middle income country in an open-label randomized controlled trial using a dedicated APP implementation team and wearable continuous-monitoring devices.

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Article Synopsis
  • - The study examined how nutrition-related symptoms affect the quality of life (QoL) for advanced non-small cell lung cancer (NSCLC) patients, using assessments like the PG-SGA and EORTC QLQ-LC13 tools.
  • - Data was collected from 170 patients undergoing chemotherapy, revealing that poor nutritional status is significantly linked to a decline in QoL.
  • - While some symptoms, like cough and shortness of breath, showed a moderate positive correlation with nutritional assessments, many other symptoms had weak correlations, indicating that focusing solely on nutrition may not sufficiently improve QoL for these patients.
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, a causative agent of quartan malaria, is prevalent across tropical and subtropical regions, but global cases have been usually very rare and sporadic. However, a significant outbreak of quartan malaria caused by occurred in Khanh Vinh District, Khanh Hoa Province, Vietnam in 2023 and the outbreak persists. In this report, we present the epidemiological and clinical characteristics of this unprecedented outbreak of quartan malaria in Vietnam.

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In the field of healthcare, quality and efficiency are of paramount importance to ensure the provision of safe and reliable diagnostic services. Blood screening laboratories play a critical role in detecting and preventing the spread of infectious diseases, ensuring the safety of blood transfusions, and supporting medical diagnoses. To enhance the quality of processes in such laboratories, the Six Sigma methodology has gained significant recognition for its ability to systematically identify and minimize variations, thereby improving overall efficiency and reducing errors.

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Article Synopsis
  • * LMICs face challenges like limited funding, outdated tech, and lack of expertise, making it difficult to apply AI models developed in HICs without adaptation.
  • * The study assesses the use of UK-developed AI models in Vietnam, highlighting the need for personalized approaches to improve performance and address local healthcare challenges effectively.
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(1) Background: Atrial fibrillation (AF) poses a growing cardiovascular challenge globally, with significant implications in Vietnam. This study aimed to investigate the impact of AF on ischemic stroke/transient ischemic attack (TIA) and clinical outcomes, as well as the utilization of oral anticoagulation (OAC) therapy in Vietnam. (2) Methods: Data from the Registry of Stroke Care Quality (RES-Q) across 66 hospitals in Vietnam between 2017 and 2023 were utilized.

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We studied a community cluster of 25 mpox cases in Vietnam caused by emerging monkeypox virus sublineage C.1 and imported into Vietnam through 2 independent events; 1 major cluster carried a novel APOBEC3-like mutation. Three patients died; all had advanced HIV co-infection.

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Omental torsion is a medical condition characterized by the twisting of the omentum along its longitudinal axis, which leads to compromised blood flow. This condition is rarely diagnosed before surgery and can present symptoms similar to other causes of acute surgical abdomen. This report details a case of primary omental torsion initially suspected to be acute appendicitis.

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Article Synopsis
  • Acute appendicitis is a common emergency usually caused by things like fecal obstruction or swollen lymph nodes, but foreign body ingestion is a rare cause, especially in kids.
  • A case study of a 9-year-old boy showed that a bone fragment he ingested was responsible for his appendicitis.
  • The report highlights the need for thorough clinical evaluations and proper imaging techniques to ensure effective treatment for pediatric patients with appendicitis.
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  • Controllable Pareto front learning (CPFL) focuses on finding optimal solutions within a given constraint region instead of the entire decision space.
  • The approach aims to address split multi-objective optimization problems while adhering to specific constraints.
  • A new hyper-transformer model (Hyper-Trans) is introduced as an improvement over the previous Hyper-MLP model, demonstrating better performance in minimizing MED errors during computational experiments.
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Objectives: We studied the immunogenicity after primary and booster vaccinations of the Abdala COVID-19 vaccine, a receptor-binding domain protein subunit vaccine, in Vietnamese people by determining the level of neutralization and cross-neutralization activities against the ancestral SARS-CoV-2 and its variants and SARS-CoV-1.

Methods: We performed a prospective observational study, enrolling adults aged 19-59 years in Dong Thap province, southern Vietnam, and collected blood samples from baseline until 4 weeks after the booster dose. We measured anti-nucleocapsid, anti-spike, and neutralizing antibodies against SARS-CoV-2 and assessed the cross-neutralization against 14 SARS-CoV-2 variants and SARS-CoV-1.

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Introduction: Total hip arthroplasty with traditional stem joints, although bringing many benefits to patients indicated for hip replacement, faces many difficulties in reoperations in young patients due to the limited lifespan of the artificial joint. Recently, the short-stem joint was introduced to help overcome this problem. This study aims to evaluate the results of short-stem implants for primary total hip arthroplasty in Vietnamese adults.

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Objective: To determine the angiographic severity of coronary artery disease (CAD) and assess the influence of major cardiovascular risk factors (CVRF).

Study Design: a cross-sectional, hospital-based study.

Setting: the catheterisation laboratory of the National Cardiothoracic Centre, Accra, Ghana.

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Alterations in signaling pathways and modulation of cell metabolism are associated with the pathogenesis of cancers, including hepatocellular carcinoma (HCC). Small ubiquitin-like modifier (SUMO) proteins and NF-κB family play major roles in various cellular processes. The current study aims to determine the expression profile of SUMO and NF-κB genes in HCC tumors and investigate their association with the clinical outcome of HCC.

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: Malaria continues to be a significant global health challenge. The efficacy of artemisinin-based combination therapies (ACTs) has declined in many parts of the Greater Mekong Subregion, including Vietnam, due to the spread of resistant malaria strains. This study was conducted to assess the efficacy of the Dihydroartemisinin (DHA)-Piperaquine (PPQ) regimen in treating uncomplicated malaria and to conduct molecular surveillance of antimalarial drug resistance in Binh Phuoc and Dak Nong provinces.

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Article Synopsis
  • Collaborative AI partnerships between high-income countries (HICs) and low- to middle-income countries (LMICs) are becoming more frequent, mainly due to resource challenges in LMICs.
  • Ensuring fairness and equity in these collaborations is critical, as differences between HIC and LMIC hospitals can impact performance outcomes.
  • The study, through a COVID-19 screening case study, shows that using bias mitigation methods in algorithms can enhance outcome fairness and maintain diagnostic accuracy across both settings.
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CuCoFe-LDO/BCD was successfully synthesized from CuCoFe-LDH and biochar derived from durian shell (BCD). Ciprofloxacin (CFX) degraded more than 95% mainly by O and O in CuCoFe-LDO/BCD(2/1)/PMS system within 10 min with a rate constant of 0.255 min, which was 14.

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Pneumorrhachis (PR) is an uncommon condition characterized by the accumulation of air within the spinal canal. This finding may occur due to various causes, mostly after trauma and medical procedures. It can manifest with various features depending on the underlying cause, the location, and the extent of the air trapped.

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Three new oleanane-type triterpene saponins, named camphanosides A-C (1-3), along with five known compounds, chikusetsusaponin IVa (4), spinasaponin A 28-O-glucoside (5), (-)-epicatechin (6), (-)-epicatechin 3-O-gallate (7), and (-)-epigallocatechin 3-O-gallate (8) were isolated from the leaves Camellia phanii Hakoda & Ninh. Their structures were established by 1D and 2D-NMR and mass spectral analysis and chemical methods. Moreover, compounds 1-5 were also evaluated for α-glucosidase inhibitory activity.

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