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View Article and Find Full Text PDFCancer has emerged as a significant global health challenge, ranking as the second leading cause of death worldwide. Moreover, cancer patients frequently experience compromised immune systems, rendering them susceptible to bacterial infections. Combining anticancer and antibacterial properties in a single drug could lead to improved overall treatment outcomes and patient well-being.
View Article and Find Full Text PDFThe development of heavy-atom-free photosensitizers (PSs) for photodynamic therapy (PDT) has encountered significant challenges in achieving simultaneous high fluorescence emission and reactive oxygen species (ROS) generation. Moreover, the limited water solubility of these PSs imposes further limitations on their biomedical applications. To overcome these obstacles, this study presents a molecular design strategy employing hydrophilic heavy-atom-free PSs based on imidazolium salts.
View Article and Find Full Text PDFNasopharyngeal carcinoma (NPC) is the most common cancer among head and neck cancers in Vietnam. We aimed to identify the rate of a 30 bp deletion mutation of the LMP1-EBV gene in nasopharyngeal biopsy tissue samples, the HLA genotypes of NPC patients, and the relationship between these two targets. Patients with NPC at Can Tho Oncology Hospital from September 2014 to December 2018 were selected.
View Article and Find Full Text PDFBackground: The BRAF gene encodes for the mutant BRAF protein, which triggers downstream oncogenic signaling in thyroid cancer. Since most currently available methods have focused on detecting BRAF mutations in tumor DNA, there is limited information about the level of BRAF mRNA in primary tumors of thyroid cancer, and the diagnostic relevance of these RNA mutations is not known.
Methods: Sixty-two patients with thyroid cancer and non-malignant thyroid disease were included in the study.
Ultra-miniaturized microendoscopes are vital for numerous biomedical applications. Such minimally invasive imagers allow for navigation into hard-to-reach regions and observation of deep brain activity in freely moving animals. Conventional solutions use distal microlenses.
View Article and Find Full Text PDFObjectives: To determine DNA-HPV transition rates and related factors in HPV-infected women 18-69 years of age in Can Tho City from 2013 to 2018.
Methods: Both a retrospective and a prospective cohort study were done. Interviews, gynaecological examinations and HPV testing by PCR (cervical fluid) were used to collect data.
A single-pixel compressively sensed architecture is exploited to simultaneously achieve a 10× reduction in acquired data compared with the Nyquist rate, while alleviating limitations faced by conventional widefield temporal focusing microscopes due to scattering of the fluorescence signal. Additionally, we demonstrate an adaptive sampling scheme that further improves the compression and speed of our approach.
View Article and Find Full Text PDFWe demonstrate a photonic system for pseudorandom sampling of multi-tone sparse radio-frequency (RF) signals in an 11.95-GHz bandwidth using <1% of the measurements required for Nyquist sampling. Pseudorandom binary sequence (PRBS) patterns are modulated onto highly chirped laser pulses, encoding the patterns onto the optical spectra.
View Article and Find Full Text PDFWe demonstrate an imaging system employing continuous high-rate photonically-enabled compressed sensing (CHiRP-CS) to enable efficient microscopic imaging of rapidly moving objects with only a few percent of the samples traditionally required for Nyquist sampling. Ultrahigh-rate spectral shaping is achieved through chirp processing of broadband laser pulses and permits ultrafast structured illumination of the object flow. Image reconstructions of high-speed microscopic flows are demonstrated at effective rates up to 39.
View Article and Find Full Text PDFBackground: The People's Republic of Vietnam is currently in a period of transition from a purely socialistic country towards a so-called socialist market economy. Since the introduction of the Doi Moi policy in 1987, health care services have been liberalized, medical practitioners have received the right to open private hospitals and private pharmacies are booming. However, the majority of inhabitants strongly depends on governmental hospital services.
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