Seasonal Characterization of the Aerobiome in Hematopoietic Stem Cell Transplant Rooms: Potential Risk for Immunosuppressed Patients.

Infections pose a risk for patients undergoing hematopoietic stem cell (HSC) transplants due to their immunosuppression, making them susceptible to opportunistic infections. Therefore, understanding the composition of the aerobiome in this area is vital. The aim of this study was to characterize the aerobiome in an HSC transplant area, evaluating the impact of infrastructure and health personnel operations on air contamination.

Plasma Photoinactivation of Bacterial Isolated from Blood Donors Skin: Potential of Security Barrier in Transfusional Therapy.

The presence of skin bacteria capable of forming biofilm, exhibiting antibiotic resistance, and displaying virulence represents a significant challenge in the field of transfusion medicine. This underscores the necessity of enhancing the microbiological safety of blood and blood components against pathogens with virulent characteristics. The aim of this work was to demonstrate bacterial inactivation in plasma by using a photoinactivation method against virulent bacteria and to evaluate coagulation factors before and after treatment.

Molecular Characterization of Bacterial Agents Causing External Ocular Infections Isolates of Patients in a Third Level Hospital.

Empirical use of antibiotics in the treatment of eye infections leads to bacterial pathogens becoming resistant to antibiotics; consequently, treatment failure and eye health complications occur. The aim of this study was to describe the phenotype and genotype of the resistance and adherence of bacterial agents causing eye infections in patients at Hospital Juárez de México. An observational, prospective, cross-sectional, and descriptive study was carried out in patients with signs and symptoms of ocular infection.

Epidemiological Overview of Urogenital Gonorrhea in Mexico (2003-2020).

In Mexico, urogenital gonorrhea (UG) is one of the main sexually transmitted diseases notifiable by health systems around the world. Epidemiological data on sexually transmitted infections (STIs) in Mexico indicated that UG was "under control" until 2017. However, international epidemiological reports indicate the increase in incidence due to several factors, including an increase during the first year of the COVID-19 pandemic.

Disinfection efficacy of ozone on ESKAPE bacteria biofilms: Potential use in difficult-to-access medical devices.

Background: Medical devices can be reservoirs of multidrug-resistant bacteria that may be involved in the acquisition of infections since bacteria with the ability to form biofilms that are difficult to eradicate, mainly in mechanical ventilators. The aim of this work was to evaluate the efficacy of O against biofilms of bacteria ESKAPE group through disinfection studies.

Methods: The formation of biofilms of ESKAPE group bacteria was induced in vitro.

Compensatory contribution of retinal larger vessels to perfusion density in diabetics without retinopathy.

Vessel and perfusion densities may decrease before diabetic retinopathy appears; it is unknown whether these changes affect the contribution of vessel density to perfusion density. This was a non-experimental, comparative, prospective, cross-sectional study in non-diabetic subjects (group 1) and diabetics without retinopathy (group 2). Vessel and perfusion densities in the superficial capillary plexus were compared between groups at the center, inner, and full regions and by field (superior, temporal, inferior, nasal) using optical coherence tomography angiography.

Impact of the modification of a cleaning and disinfection method of mechanical ventilators of COVID-19 patients and ventilator-associated pneumonia: One year of experience.

Background: Mechanical ventilators are essential biomedical devices for the respiratory support of patients with SARS-CoV-2 infection. These devices can be transmitters of bacterial pathogens. Therefore, it is necessary to implement effective disinfection procedures.

[Comparación de la densidad capilar parafoveal entre sujetos sanos y diabéticos con y sin retinopatía].

Background: Parafoveal capillary density changes have not been characterized in type 2 diabetics without retinopathy.

Objective: To compare parafoveal capillary density between healthy subjects, and diabetics with and without retinopathy.

Method: Observational, prospective, transversal and comparative study; subjects without diabetes (group 1), diabetics without retinopathy (group 2), with retinopathy (group 3) and with diabetic macular edema (group 4), without macular ischemia, were included.

[Association between visual improvement after photocoagulation and the use of angiotensin converting enzyme inhibitors in diabetic macular oedema].

Background: Angiotensin converting enzyme inhibitors are effective in delaying the progression of diabetic retinopathy. It is unknown if their use is associated with a better visual outcome in patients with diabetic macular oedema.

Material And Methods: A non-experimental, comparative, longitudinal and retrospective study was performed on patients with diabetic macular oedema treated by focal photocoagulation, and with systemic arterial hypertension treated with angiotensin converting enzyme inhibitors (Group 1), and without hypertension (Group 2).

[Expected effect of retinal thickness after focal photocoagulation in diabetic macular oedema].

Background: Macular oedema is a form of diabetic retinopathy that can be treated with photocoagulation. The expected effect of treatment varies, and may depend on the previous characteristics of retinal thickening.

Objective: To determine whether the change in retinal thickness after focal photocoagulation for diabetic macular oedema varies due to the presence of anatomical features that may justify a separate assessment.

[Lack of correlation between retinal variables before treatment and poor functional response after focal photocoagulation in diabetic macular oedema].

Background: Although photocoagulation reduces the incidence of moderate visual loss in eyes with focal diabetic macular oedema, some eyes may lose some vision after treatment. The proportion of eyes with poor functional response after photocoagulation, and whether any retinal variable is associated with this, is unknown.

Objective: To determine the proportion of eyes with diabetic macular oedema that have a poor functional response after focal photocoagulation, and their associated features.

[Features associated with retinal thickness extension in diabetic macular oedema].

Background: Clinically significant macular edema has features that are associated with a major risk of visual loss, with thickening that involves the centre of the macula, field 7 or visual deficiency, although it is unknown if these features are related to retinal thickness extension.

Material And Methods: An observational, analytical, prospective, cross-sectional and open study was conducted. The sample was divided into initial visual acuity ≥0.

[Ocular Trauma Score comparison with open globe receiving early or late care attention].

Background: The Ocular Trauma Score (OTS) is a scale that estimates the prognosis of injured eyes after treatment, whose results are consistent with those of longitudinal studies. The time between injury presentation and initial care has been described as a prognostic factor for visual outcome, but the OTS features of eyes receiving early or late care after trauma have not been compared.

Material And Methods: Non-experimental, comparative, retrospective, cross sectional study.

[Efficacy of dorzolamide in reducing retinal thickness after photocoagulation in diabetic macular oedema].

Background: Focal photocoagulation interrupts vascular leakage in diabetic macular edema, and allows the retinal pigment epithelium to withdraw fluid that thickens the retina; this mechanism could be enhanced by dorzolamida, a topical carbonic anhydrase inhibitor.

Objective: To determine the efficacy of dorzolamida compared against placebo, in reducing retinal thickness after focal photocoagulation, in eyes with diabetic macular oedema.

Material And Methods: Experimental, comparative, prospective, longitudinal, double blind study in diabetics with focal macular oedema treated with photocoagulation.

Retinal thickness after focal photocoagulation for diabetic macular edema with and without temporal perifoveal thickening.

Background: Visual improvement after focal photocoagulation in diabetic macular edema is more common in eyes without temporal perifoveal thickening. This feature is related to a lower macular volume before treatment; the higher proportion of visual improvement could be associated with a shorter need of volume reduction.

Objective: To compare macular volume before and after focal photocoagulation in eyes with diabetic macular edema, with and without temporal perifoveal thickening.

[Retinal sensitivity in diabetic macular edema, with and without decreased visual acuity].

Objective: To compare retinal sensitivity in diabetics with macular edema, with and without decreased visual acuity.

Methods: An observational, prospective, cross-sectional comparative study in eyes with diabetic macular edema. The sample was divided into two groups: eyes with visual acuity ""≥ 0.

[Efficacy of topical ketorolac for improving visual function after photocoagulation in diabetic patients with focal macular edema].

Background: Photocoagulation reduces the incidence of visual loss in diabetic patients with focal macular edema, but it can induce it for Efficacy of topical ketorolac for improving visual function after photocoagulation in diabetic patients with focal macular edema 6 weeks after treatment and produces visual improvement in some cases. Topical ketorolac may reduce the inflammation caused by photocoagulation and improve visual outcome.

Purpose: To determine the efficacy of topical ketorolac for improving visual function after photocoagulation in diabetic patients with focal macular edema.

[Status of center point thickness and correlation between anatomic and best corrected visual acuity changes after photocoagulation, in diabetic macular edema].

Background: Center point thickness in diabetic macular edema varies after photocoagulation according to its baseline status; it is unknown whether this variation reduces the correlation between anatomic and visual acuity changes.

Objective: to identify the contribution of baseline center point thickness to the correlation between anatomic and visual acuity after photocoagulation, in eyes with diabetic macular edema.

Methods: non-experimental, prospective, longitudinal, analytical study in diabetics with macular edema treated with photocoagulation, stratified by groups: visual acuity < 0.

[Comparison of macular volume change after photocoagulation, in eyes with diabetic macular edema, with and without visual improvement].

Objective: To compare the changes in macular volume after photocoagulation between eyes with diabetic macular edema with and without visual improvement.

Methods: Non-experimental, retrospective, longitudinal, comparative study in eyes with diabetic macular edema; the sample was divided in groups: eyes with visual improvement three weeks after photocoagulation (group 1) and eyes without it (group 2). The means of macular volume changes (potential, absolute and percentage) were compared between groups (Student's t test).

[Impact of follow-up loss over visual deficiency in open-globe ocular trauma].

Introduction: Open-globe ocular trauma causes visual deficiency; calculating the magnitude of the latter often misses the estimation in patients without follow-up.

Aim: to identify the modification of the postoperative proportion of visual deficiency in open-globe ocular trauma, which would introduce considering the proportion estimated in patients without follow-up.

Methods: Non-interventional, retrospective, longitudinal, analytical study.

[Can visual outcome be improved in open globe ocular trauma?].

Background: Visual prognosis of injured eyes estimated by the Ocular Trauma Score (OTS) can be used to evaluate the efficacy of open globe treatment. The aim of this study was to identify the OTS features over which interventions could be performed to improve visual outcome in patients with open globe trauma.

Methods: We carried out an observational, longitudinal, retrospective-prospective, analytical study.

[Characteristics associated with visual improvement after focal photocoagulation in diabetic macular edema].

Background: Photocoagulation reduces the incidence of moderate visual loss in patients with clinically significant macular edema (CSME). However, the incidence of visual improvement after treatment is low. Diffuse retinal thickening identified with optical coherence tomography (OCT) and visual loss before treatment have been associated with visual improvement.

[Efficacy of clinical evaluation in diagnosing injury zone in open globe ocular trauma].

Background: Risk of retinal damage in open globe eye injuries increases as the zone (location of the wound vertex) is more rearward. The value of clinical exploration to assess this variable is unknown.

Objective: To establish the efficacy of clinical exploration as a diagnostic test to identify the injury zone in open globe ocular trauma.

Expected value of foveal thickness in macular edema in Mexican patients with diabetes.

Background: The tomographic cut-off point to detect macular edema uses an international reference of retinal thickness, which is greater than that in our population. We undertook this study to identify the expected value of central subfield mean thickness (CSMT) in Mexican patients with diabetes with clinically significant macular edema (CSME) and the proportion in which using only the tomographic cut-off point for clinical macular edema (>300 μm) could overlook the diagnosis.

Methods: We carried out an observational, analytical, crosssectional and prospective study.

Disparity between foveal thickness and macular volume in diabetic macular edema.

Background: Optical coherence tomography (OCT) quantifies changes of foveal thickness and macular volume after photocoagulation in diabetic macular edema. Macular volume evaluates the whole macula, but it may underestimate changes in foveal thickness induced by photocoagulation. We undertook this study to evaluate the concordance between macular volume and foveal thickness for identifying clinically significant changes of retinal thickness after photocoagulation for diabetic macular edema.