Publications by authors named "Dulce M Macias Diaz"
In Mexico, chronic kidney disease of unknown origin is highly prevalent. Screening studies in adolescents have shown persistent microalbuminuria (pACR), adaptive podocytopathy and decreased kidney volume (KV). Here, we sought to develop normality tables of kidney dimensions by ultrasound in the Mexican state of Aguascalientes pediatric population (0 to 18y) and evaluate the relationship between the KV and pACR among the region's adolescents in a cross-sectional study.
View Article and Find Full Text PDFHistologic characterization and risk factors for persistent albuminuria in adolescents in a region of highly prevalent end-stage renal failure of unknown origin.
Clin Kidney J
July 2022
Article Synopsis
- - The study investigates the high prevalence of end-stage renal failure of unknown origin (ESRD-UO) among adolescents in Aguascalientes, Mexico, particularly affecting 20-40 year-olds, by screening for chronic kidney disease (CKD) and identifying associated risk factors.
- - In analyzing 513 students, the research found that 3.7% exhibited persistent albuminuria, though there were no significant homeostatic or anatomical abnormalities detected through renal ultrasound; however, those with albuminuria did show reduced total renal volume.
- - Kidney biopsies revealed glomerulomegaly and various podocyte abnormalities, with identified risk factors linked to environmental exposures and family health history, while a higher BMI and breastfeeding appeared
Background: In the last decade, kidney donation has been recognized as a risk factor for end-stage renal disease (ESRD). ESRD risk calculators have been recently perfected in North American populations. In Mexico, the rates of overweight, obesity, and diabetes mellitus (DM) are among the highest worldwide; nevertheless, most kidney transplants are obtained from living donors.
View Article and Find Full Text PDFHigh prevalence of end-stage renal disease of unknown origin in Aguascalientes Mexico: role of the registry of chronic kidney disease and renal biopsy in its approach and future directions.
Clin Kidney J
April 2021
Background: Chronic kidney disease (CKD) is one of the pathologies with the greatest impact on the public health system. Over the last few decades, the relevance of CKD in Mexico has increased, with associated overwhelming costs for care of renal disease. There are no reliable CKD statistics in Mexico.
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