The significance of immunohistochemically demonstrated nodal micrometastases in patients with squamous cell carcinoma of the head and neck.

Objectives/hypothesis: Patients with primary squamous cell carcinoma of the head and neck have a relatively high risk of occult lymph node metastases. Pathological demonstration of these metastases may be difficult, and the detection of such occult metastases may identify patients who are at an increased risk for early recurrence or reduced survival. Immunohistochemistry may be applied in the identification of occult metastases that may be missed on routine (H&E) histological examination.

Recurrent attacks of facial nerve palsy as the presenting sign of leukemic relapse.

Objective: To present an unusual case of recurrent facial palsy resulting from acute leukemic infiltration of the parotid gland.

Study Design: Case report.

Methods: An 11-year-old boy who had been treated for acute lymphoblastic leukemia (ALL) from 3 to 6 years of age presented with intermittent left facial nerve palsy with concurrent ipsilateral parotid fullness.