Publications by authors named "Duen-Huey Tan"
Article Synopsis
- The hemagglutinin cleavage site (HA CS) sequences are crucial in determining how pathogenic H5N2 avian influenza viruses are.
- Two new HA CS sequences (QKEKR/GL and KREKREKR/GL) were identified in viruses from 2013-2014, with distinct pathogenicity levels linked to each sequence.
- In 2015, all isolated viruses shared the QREKR/GL sequence, which was associated with low pathogenicity, highlighting the ability of these viruses to evolve and adapt their pathogenic traits over time.
Avibacterium paragallinarum is the causative agent of infectious coryza, an important respiratory disease of chickens. The capsule is an important virulence determinant of many pathogenic bacteria, but the function of the capsule in Av. paragallinarum is not well defined.
View Article and Find Full Text PDFThe haemagglutinin (HA) protein plays a key role in the immunogenicity and pathogenicity of Avibacterium paragallinarum. A 210-kDa protein (HMTp210) was previously reported to be the HA of Av. paragallinarum, but the biological function of HMTp210 is not well defined.
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- Peperomia sui, a Taiwanese folk medicine, has shown potential for treating upper respiratory diseases but has not been previously studied for its effects on influenza virus infections.* -
- This research evaluated the ethanolic extract of Peperomia sui (PSE) against the H6N1 avian influenza virus using various assays to determine its antiviral properties.* -
- Results indicated that PSE elevated cell viability in H6N1-infected cells, suppressed viral nucleoprotein production, and inhibited the virus's growth and neuraminidase activity, suggesting its potential utility in influenza treatment.*
Avibacterium paragallinarum is the causative agent of infectious coryza, an important respiratory disease of chickens. Whole-genome sequencing analysis showed that A. paragallinarum strain H18 contains an RTX toxin-like operon with strong similarity to the RTX operons of other members of the Pasteurellaceae.
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