Urban gardening education: User reflections on mobile application designs.

Mobile gardening applications offer a wide range of opportunities to shape the environmental behaviour of city dwellers, while stimulating action for greater access and contact with nature. Despite this, their educational potential is not sufficiently recognised and exploited. The aim of this qualitative research is to gain an in-depth understanding of the extent to which existing mobile apps can facilitate digital education for the development of green cities.

Attributional and attentional patterns in the perception of ambiguous harmful encounters involving peer and authority figures.

Background: Self-construal influences the way people ascribe blame to victims, but it is not clear whether the same applies to harm doers, especially those in a position of authority.

Participants And Procedure: We examined ( = 122, men = 60) participants' ascriptions of both blame and intentionality to harm doers (authority figure versus peer) while priming self-construal (relational versus individual self). Using eye-tracking, we explored whether priming relational self, compared to individual self, affects the allocation of attention to faces versus objects.

Understanding Health-Related Motivations for Urban Food Self-Production in the Light of Semantic Fields Analysis.

One of the contemporary challenges facing urban areas is the necessity to identify novel approaches to resident involvement in solution creation, with a particular focus on ensuring the best possible nutrition. By investigating the process of co-participation of city dwellers in a unique education project, this paper aims to gain a deeper understanding of the health-related motivations that underpin the decision of early adopters of the implemented technological innovations to join the social experiment. The qualitative study employed purposive sampling and in-depth interviews conducted in two waves, the first between October and November 2022 and the second between September 2023 and January 2024.

An Oligomer Approach for Blue Thermally Activated Delayed Fluorescent Emitters Based on Twisted Donor-Acceptor Units.

The development of efficient blue donor-acceptor thermally activated delayed fluorescence (TADF) emitters remains a challenge. To enhance the efficiency of TADF-related processes of the emitter, we targeted a molecular design that would introduce a large number of intermediate triplet states between the lowest energy excited triplet (T) and singlet (S) excited states. Here, we introduce an oligomer approach using repetitive donor-acceptor units to gradually increase the number of quasi-degenerate states.

How much (evil) intelligence can be encoded by 30 kb?

Genomes of most RNA viruses are rarely larger than the size of an average human gene (10-15 kb) and still code for a number of biologically active polypeptides that modify the immune system and metabolism of the host organism in an amazingly complex way. Prolonged coevolution developed tricks by which viruses can dodge many protective mechanisms of the host and lead to the formation of molecular mimicry patterns. Some viruses inhibit the interferon response, interfere with the membrane destroying effects of the activated complement cascade.

Greencoin as an AI-Based Solution Shaping Climate Awareness.

Our research aim was to define possible AI-based solutions to be embedded in the Greencoin project, designed as a supportive tool for smart cities to achieve climate neutrality. We used Kamrowska-Załuska's approach for evaluating AI-based solutions' potential in urban planning. We narrowed down the research to the educational and economic aspects of smart cities.

Comparison of Targeted and Routine Adolescent HIV Screening in a Pediatric Emergency Department.

Objectives: The aims of the study were (1) to compare targeted and routine HIV screening in a pediatric emergency department (PED) and (2) to compare provider documented HIV risk assessment with adolescent perception of HIV risk assessment conducted during the PED visit.

Methods: This prospective study ran concurrent to a PED routine HIV screening pilot. Adolescents could be tested for HIV by the PED provider per usual care (targeted testing); if not tested, they were approached for the routine screening pilot.

Regiochemistry of Donor Dendrons Controls the Performance of Thermally Activated Delayed Fluorescence Dendrimer Emitters for High Efficiency Solution-Processed Organic Light-Emitting Diodes.

The potential of dendrimers exhibiting thermally activated delayed fluorescence (TADF) as emitters in solution-processed organic light-emitting diodes (OLEDs) has to date not yet been realized. This in part is due to a poor understanding of the structure-property relationship in dendrimers where reports of detailed photophysical characterization and mechanism studies are lacking. In this report, using absorption and solvatochromic photoluminescence studies in solution, the origin and character of the lowest excited electronic states in dendrimers with multiple dendritic electron-donating moieties connected to a central electron-withdrawing core via a para- or a meta-phenylene bridge is probed.

Thermally Activated Delayed Fluorescent Dendrimers that Underpin High-Efficiency Host-Free Solution-Processed Organic Light-Emitting Diodes.

The development of high-performance solution-processed organic light-emitting diodes (OLEDs) remains a challenge. An effective solution, highlighted in this work, is to use highly efficient thermally activated delayed fluorescence (TADF) dendrimers as emitters. Here, the design, synthesis, density functional theory (DFT) modeling, and photophysics of three triazine-based dendrimers, tBuCz2pTRZ, tBuCz2mTRZ, and tBuCz2m2pTRZ, is reported, which resolve the conflicting requirements of achieving simultaneously a small ΔE and a large oscillator strength by incorporating both meta- and para-connected donor dendrons about a central triazine acceptor.

Diindolocarbazole - achieving multiresonant thermally activated delayed fluorescence without the need for acceptor units.

In this work we present a new multi-resonance thermally activated delayed fluorescence (MR-TADF) emitter paradigm, demonstrating that the structure need not require the presence of acceptor atoms. Based on an design, the compound DiICzMes4 possesses a red-shifted emission, enhanced photoluminescence quantum yield, and smaller singlet-triplet energy gap, Δ, than the parent indolocarbazole that induces MR-TADF properties. Coupled cluster calculations accurately predict the magnitude of the Δ when the optimized singlet and triplet geometries are used.

Reduced attention toward faces, intentionality and blame ascription in violent offenders and community-based adults: Evidence from an eye-tracking study.

People typically have a strong bias in attention toward faces to help them understand social interactions. Nonetheless some people, like incarcerated offenders and psychopaths, exhibit deficits in "face reading," which may impair their interpretations, especially in case of attribution allocation in harmful events. In these cases, the ascription of intentionality is key in understanding the allocation of blame and structuring social information processing.

Enhancing Thermally Activated Delayed Fluorescence by Fine-Tuning the Dendron Donor Strength.

Thermally activated delayed fluorescence (TADF) relies on a small energy gap between the emissive singlet and the nonemissive triplet state, obtained by reducing the wave function overlap between donor and acceptor moieties. Efficient emission, however, requires maintaining a good oscillator strength, which is itself based on sufficient overlap of the wave functions between donor and acceptor moieties. We demonstrate an approach to subtly fine-tune the required wave function overlap by employing donor dendrons of changing functionality.

Visible Light-Generated Antiviral Effect on Plasmonic Ag-TiO-Based Reactive Nanocomposite Thin Film.

The recent coronavirus pandemic pointed out the vulnerability of humanity to new emerging infectious diseases. Experts warn that future pandemics may emerge more frequently with greater devastating effects on population health and the world economy. Although viruses are unable to propagate on lifeless surfaces, they can retain their infectivity and spread further on contact with these surfaces.

High Triplet Energy Host Materials for Blue TADF OLEDs-A Tool Box Approach.

The synthesis of stable blue TADF emitters and the corresponding matrix materials is one of the biggest challenges in the development of novel OLED materials. We present six bipolar host materials based on triazine as an acceptor and two types of donors, namely, carbazole, and acridine. Using a tool box approach, the chemical structure of the materials is changed in a systematic way.

Unique Needs for the Implementation of Emergency Department Human Immunodeficiency Virus Screening in Adolescents.

Background: The Centers for Disease Control and Prevention (CDC) recommend universal human immunodeficiency virus (HIV) screening starting at 13 years, which has been implemented in many general U.S. emergency departments (EDs) but infrequently in pediatric EDs.

[Opportunity of periodic monitoring of COVID-19 patients, asymptomatic virus carriers, and postinfectious individuals with IgM/IgG rapid antibody tests among healthcare workers during SARS-CoV-2 pandemic].

The first Hungarian COVID-19 case was reported on March 4, 2020 by Hungarian officials. Healthcare workers (HCWs) are at the highest risk of contracting the novel coronavirus (SARS-CoV-2), with 12% of total coronavirus cases confirmed among them recently. 80% of the infected persons show only mild, moderate symptoms or stay asymptomatic.

A Deep Blue B,N-Doped Heptacene Emitter That Shows Both Thermally Activated Delayed Fluorescence and Delayed Fluorescence by Triplet-Triplet Annihilation.

An easy-to-access, near-UV-emitting linearly extended B,N-doped heptacene with high thermal stability is designed and synthesized in good yields. This compound exhibits thermally activated delayed fluorescence (TADF) at ambient temperature from a multiresonant (MR) state and represents a rare example of a non-triangulene-based MR-TADF emitter. At lower temperatures triplet-triplet annihilation dominates.

Primary Care in Transgender Persons.

The preventive health care needs of transgender persons are nearly identical to the rest of the population. Special consideration should be given, however, to the impact of gender-affirming hormone regimens and surgical care on preventive screenings. Providers should integrate a more comprehensive view of health when caring for transgender persons and address the impact of social determinants and other barriers to accessing affirming, inclusive health care.

Contribution of syndecans to lipoplex-mediated gene delivery.

The long awaited breakthrough of gene therapy significantly depends on the in vivo efficiency of targeted intracellular delivery. Hidden details of cellular uptake present a great hurdle for non-viral gene delivery with liposomes. Growing scientific evidence supports the involvement of polyanionic cell surface carbohydrates in cellular internalization of cationic liposomes.

Casein kinase 2-interacting protein-1, an inflammatory signaling molecule interferes with TNF reverse signaling in human model cells.

When transmembrane form of tumor necrosis factor (mTNF) interacts with its cognate receptors or agonistic antibodies signaling pathways are activated in the ligand expressing cells. This "reverse signaling" appears a fine-tuning control mechanism in the immune response. Despite a clinical relevance key molecules of TNF reverse signaling and their functions remain elusive.

Importance of reverse signaling of the TNF superfamily in immune regulation.

TNF-related ligands (with the exception of lymphotoxin-α) are synthesized as type II transmembrane proteins, though many of them also have soluble forms. An increasing number of publications report that these 'ligands' behave as receptors, activating intracellular signaling pathways when interacting with cognate 'receptors' or agonistic antibodies. Most members of the TNF family and their receptors influence survival, proliferation, differentiation or activation of immune cells.

Interactions between LPS moieties and macrophage pattern recognition receptors.

Mammalian host organisms live their life constantly interacting with pathogenic and non-pathogenic Gram-negative bacteria. Commensal/symbiont strains are tolerated in the gut, while pathogens are kept at bay by the immune system. In contrast both commensals and pathogenic bacteria are targets of the immune system outside of the digestive system.

Lysosomal rerouting of Hsp70 trafficking as a potential immune activating tool for targeting melanoma.

Tumor specific cell surface localization and release of the stress inducible heat shock protein 70 (Hsp70) stimulate the immune system against cancer cells. A key immune stimulatory function of tumor-derived Hsp70 has been exemplified with the murine melanoma cell model, B16 overexpressing exogenous Hsp70. Despite the therapeutic potential mechanism of Hsp70 transport to the surface and release remained poorly understood.

Melanoma cell-derived exosomes alter macrophage and dendritic cell functions in vitro.

To clarify controversies in the literature of the field, we have purified and characterized B16F1 melanoma cell derived exosomes (mcd-exosomes) then we attempted to dissect their immunological activities. We tested how mcd-exosomes influence CD4+ T cell proliferation induced by bone marrow derived dendritic cells; we quantified NF-κB activation in mature macrophages stimulated with mcd-exosomes, and we compared the cytokine profile of LPS-stimulated, IL-4 induced, and mcd-exosome treated macrophages. We observed that mcd-exosomes helped the maturation of dendritic cells, enhancing T cell proliferation induced by the treated dendritic cells.