Cardiac transplantation with increased-risk donors: Trends and clinical outcomes.

Background: Orthotopic Heart transplantation (OHT) is a definitive treatment for patients with advanced heart failure. Despite available evidence, recipients and some clinicians remain hesitant to accept organs from Increased Risk Donors (IRD). This study aims to report trends in acceptance of donors from IRD donors and long-term outcomes.

Retraction notice to "E-39 | Association Between Sodium-Glucose Co-Transporter 2 Inhibitor Use and 30-Day Outcomes after Transcatheter Aortic Valve Replacement: A Retrospective Matched Cohort Analysis" [JSCAI 3 (2024) 101800].

[This retracts the article DOI: 10.1016/j.jscai.

Characterizing the mechanics of rectangular peg-hole disassembly and the effect of the active compliance centre on the extraction force.

This paper aimed at facilitating robotized disassembly for remanufacturing by focusing on the challenge of rectangular peg-hole disassembly. The study explores all potential contact states during the rectangular peg-hole disassembly process and identifies 26 distinct conditions, 16 of which are related to jamming. The contact conditions are categorized into five groups based on the number of contacts with the surface.

Application of mesenchymal stem cells for neurodegenerative diseases therapy discovery.

Neurodegenerative diseases are central or peripheral nervous system disorders associated with progressive brain cell degeneration. Common neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis have been widely studied. However, current therapeutics only reduce the symptoms and do not ameliorate the pathogenesis of these diseases.

A New Single-Parameter Bees Algorithm.

Based on bee foraging behaviour, the Bees Algorithm (BA) is an optimisation metaheuristic algorithm which has found many applications in both the continuous and combinatorial domains. The original version of the Bees Algorithm has six user-selected parameters: the number of scout bees, the number of high-performing bees, the number of top-performing or "elite" bees, the number of forager bees following the elite bees, the number of forager bees recruited by the other high-performing bees, and the neighbourhood size. These parameters must be chosen with due care, as their values can impact the algorithm's performance, particularly when the problem is complex.

Impact of Heart Transplant Allocation Change on Waitlist Mortality and Posttransplant Mortality in Patients With Left Ventricular Assist Devices.

Background: In October 2018, the US heart transplant (HT) allocation system was revised giving patients with left ventricular assist device (LVAD) intermediate priority status. Few studies have examined the impact of this policy change on outcomes among patients with LVAD. We sought to determine how the allocation change impacted waitlist and posttransplant mortality in patients with LVAD.

Pulmonary artery mass with PIK3CA mutation after orthotopic heart transplantation.

Background: Patients can develop de novo malignancies following orthotopic heart transplantation. However, vascular tumors are not commonly described in this population.

Case Presentation: We present a 69-year-old female with a history of orthotopic heart transplantation for chemotherapy-induced cardiomyopathy who developed an incidental pulmonary artery mass six years after her transplantation.

Association of Novel Ventricular Assist Device Self-report Measures With Overall Health-Related Quality of Life.

Background: Few study authors examined factors influencing health-related quality of life (HRQOL) early after left ventricular assist device (LVAD) implantation.

Objective: The purpose of this study was to determine whether 5 novel self-report measures and other variables were significantly associated with overall HRQOL at 3 months after LVAD surgery.

Methods: Patients were recruited between October 26, 2016, and February 29, 2020, from 12 US sites.

Quantifying carbon footprint of salmon fillet processed in Vietnam: impact of transportation and improvement opportunities.

The carbon footprint of a product represents the amount of greenhouse gas (GHG) emissions released during its production, transportation, and consumption and is calculated as carbon dioxide equivalent (CO). It should be integrated into different existing and future seafood awareness campaigns to create more holistic yardsticks by which consumers, retail businesses, and producers can assess the environmental impacts of seafood. This study used the life cycle assessment (LCA) method for the first time to quantify the carbon footprint of salmon fillet products processed in Vietnam for export.

Neighborhood Socioeconomic Status and Readmission in Acute Type A Aortic Dissection Repair.

Introduction: We examined the association of socioeconomic status as defined by median household income quartile (MHIQ) with mortality and readmission patterns following open repair of acute type A aortic dissection (ATAAD) in a nationally representative registry.

Methods: Adults who underwent open repair of ATAAD were selected using the US Nationwide Readmissions Database and stratified by MHIQ. Patients were selected based on diagnostic and procedural codes.

Ventricular assist device using a thoracotomy-based implant technique: Multi-Center Implantation of the HeartMate 3 in Subjects With Heart Failure Using Surgical Techniques Other Than Full Median Sternotomy (HM3 SWIFT).

Objectives: The HeartMate 3 (Abbott) left ventricular assist device provides substantial improvement in long-term morbidity and mortality in patients with advanced heart failure. The Implantation of the HeartMate 3 in Subjects With Heart Failure Using Surgical Techniques Other Than Full Median Sternotomy study compares thoracotomy-based implantation clinical outcomes with standard median sternotomy.

Methods: We conducted a prospective, multicenter, single-arm study in patients eligible for HeartMate 3 implantation with thoracotomy-based surgical technique (bilateral thoracotomy or partial upper sternotomy with left thoracotomy).

Robotized unplugging of a cylindrical peg press-fitted into a cylindrical hole.

It is well accepted that remanufacturing, the returning of a product that has reached the end of its service life to its original condition, is economically and environmentally beneficial. Robotizing disassembly can make remanufacturing even more cost-effective by removing a substantial proportion of the labour costs associated with dismantling end-of-life products for subsequent processing. As unplugging of press-fitted components is a common operation in disassembly, it is appropriate to investigate how it can be robotized.

Age-Stratified Surgical Aortic Valve Replacement for Aortic Stenosis.

Background: The management of aortic stenosis has evolved to stratification by age as reflected in recent societal guidelines. We evaluated age-stratified surgical aortic valve replacement (SAVR) trends and outcomes in patients with bicuspid aortic valve (BAV) or tricuspid aortic valve (TAV) from The Society of Thoracic Surgeons Adult Cardiac Surgery Database.

Methods: This cohort included adults (≥18 years) undergoing SAVR for severe aortic stenosis between July 2011 and December 2022.

Anticoagulation Bridging in Patients With Left Ventricular Assist Device: A Regional Analysis of HeartMate 3 Recipients.

Advances in left ventricular assist device technologies have led to an improvement in pump hemocompatibility and outcomes. Because of concerns of thromboembolic complications in prior generations of left ventricular assist devices, bridging with parenteral anticoagulants was routinely. Management strategies of subtherapeutic INRs and their effects on the current generation of devices deserve review.

A highly sensitive fluorescence nanosensor for determination of amikacin antibiotics using composites of carbon quantum dots and gold nanoparticles.

Amikacin is an aminoglycoside antibiotic widely used to treat various bacterial infections in humans. However, elevated concentrations of amikacin can damage the cochlear nerve. Thus, accurate and rapid amikacin detection is crucial.

Dual-Organ Transplantation: Indications, Evaluation, and Outcomes for Heart-Kidney and Heart-Liver Transplantation: A Scientific Statement From the American Heart Association.

Although heart transplantation is the preferred therapy for appropriate patients with advanced heart failure, the presence of concomitant renal or hepatic dysfunction can pose a barrier to isolated heart transplantation. Because donor organ supply limits the availability of organ transplantation, appropriate allocation of this scarce resource is essential; thus, clear guidance for simultaneous heart-kidney transplantation and simultaneous heart-liver transplantation is urgently required. The purposes of this scientific statement are (1) to describe the impact of pretransplantation renal and hepatic dysfunction on posttransplantation outcomes; (2) to discuss the assessment of pretransplantation renal and hepatic dysfunction; (3) to provide an approach to patient selection for simultaneous heart-kidney transplantation and simultaneous heart-liver transplantation and posttransplantation management; and (4) to explore the ethics of multiorgan transplantation.

Change in Caregiver Health-Related Quality of Life From Before to Early After Surgery: SUSTAIN-IT Study.

Background: Information about health-related quality of life (HRQOL) among caregivers of older patients with heart failure who receive heart transplantation (HT) and mechanical circulatory support (MCS) is sparse. We describe differences and factors associated with change in HRQOL before and early post-surgery among caregivers of older heart failure patients who underwent 3 surgical therapies: HT with pretransplant MCS (HT MCS), HT without pretransplant MCS (HT non-MCS), and long-term MCS.

Methods: Caregivers of older patients (60-80 years) from 13 US sites completed the EQ-5D-3 L visual analog scale (0 [worst]-100 [best] imaginable health state) and dimensions before and 3 and 6 months post-surgery.

Transplantation Outcomes with Donor Hearts after Circulatory Death.

Background: Data showing the efficacy and safety of the transplantation of hearts obtained from donors after circulatory death as compared with hearts obtained from donors after brain death are limited.

Methods: We conducted a randomized, noninferiority trial in which adult candidates for heart transplantation were assigned in a 3:1 ratio to receive a heart after the circulatory death of the donor or a heart from a donor after brain death if that heart was available first (circulatory-death group) or to receive only a heart that had been preserved with the use of traditional cold storage after the brain death of the donor (brain-death group). The primary end point was the risk-adjusted survival at 6 months in the as-treated circulatory-death group as compared with the brain-death group.

Implementation of a direct-to-operating room aortic emergency transfer program: Expedited management of type A aortic dissection.

Introduction: Type A Aortic Dissection (TAAD) is a surgical emergency with a time-dependent rate of mortality. We hypothesized that a direct-to-operating room (DOR) transfer program for patients with TAAD would reduce time to intervention.

Methods: A DOR program was started at an urban tertiary care hospital in February 2020.

Application and planning of an energy-oriented stochastic disassembly line balancing problem.

End-of-life (EOL) products are getting more and more attention as a result of the rapid decline in environmental resources and the dramatic rise in population at the moment. Disassembly is a crucial step in the reuse of EOL products. However, the disassembly process for EOL products is highly uncertain, and the disassembly planning method may not produce the anticipated outcomes in actual implementation.

Hybrid evolutionary algorithm for stochastic multiobjective disassembly line balancing problem in remanufacturing.

With the development of the industrial economy and the accelerated renewal of products, many end-of-life products (EOL) have been generated to pollute our environment. This fact highlights the importance of recycling and remanufacturing EOL products as an active research topic. An efficient disassembly line is one solution for improving the remanufacturing and recycling processes of EOL products while reducing the environmental pollution.

Caregiver burden before heart transplantation and long-term mechanical circulatory support: Findings from the sustaining quality of life of the aged: Transplant or mechanical support (SUSTAIN-IT) study.

Background: Caregiving for heart failure (HF) patients is burdensome. We examined differences in caregiver burden for 3 groups of older advanced HF patients: (1) supported with mechanical circulatory support (MCS) before heart transplantation (HT MCS), (2) awaiting transplant without MCS (HT non-MCS), and (3) prior to long-term MCS and factors associated with burden.

Method: From October 1, 2015 to December 31, 2018, we enrolled 276 caregivers for HF patients from 13 U.