End of life breast cancer care in women with severe mental illnesses.

Little is known on the end-of-life (EOL) care of terminal breast cancer in women with severe psychiatric disorder (SPD). The objective was to determine if women with SPD and terminal breast cancer received the same palliative and high-intensity care during their end-of-life than women without SPD. Study design, setting, participants.

Anxiety and depression in young physicians: Prevalence and associated factors. The MESSIAEN national study.

Background: Physicians are at risk of anxiety and depression.

Objectives: To determine the prevalence of anxiety and depression in a national sample of young physicians and their associated factors.

Methods: The study is a cross-sectional observational epidemiological national study.

[Exposure to professional violence by young physicians in the hospital: MESSIAEN national study].

Background: Hospital professional violence is defined as hostile and aggressive behavior exerted by health professionals on other health professionals. No quantitative study has been carried out to date on French hospital professional violence among young physicians, while recent qualitative studies have suggested a potential high frequency. The main objective was to determine the prevalence of exposure of young doctors to hospital violence.

Sexual-orientation based discrimination is associated with anxiety and depression in young physicians. A national study.

Introduction: The professional risk factors for depression and anxiety are underexplored in young physicians. While there has been increasing research on the mental health and well-being of lesbian, gay and bisexual patients, few studies have examined the mental health and well-being of lesbian, gay and bisexual young physicians.

Objective: The objective of the present study was to determine the prevalence of Sexual Orientation-Based Discrimination (SOBD) in French young physicians and if SOBD was associated with increased anxiety and depression in this population.

Sexual harassment exposure and impaired mental health in medical students. The MESSIAEN national study.

Background: A previous national study has suggested that around 20% of French working women reported sexual harassment (SH) at work but we lack of data in medical students of French hospitals to guide prevention programs.

Objectives: To determine SH prevalence in a national sample of French medical students and to validate a theoretical model explaining SH causes and its impact of mental health.

Methods: The study is a cross-sectional observational epidemiological national study.

Repeated bullying at the workplace in medical students and young doctors: the MESSIAEN national study.

Despite clues indicating high Bullying at the Work Place (BWP) rates in French hospitals, there has been no quantitative study so far. To determine the prevalence of repeated BWP in a national sample of French young physicians; its risk factors, and the mental health consequences of BWP. The study is a cross-sectional observational epidemiological national study addressed to young physicians.

The Associations between Leaf Morphology, Phenylalanine Ammonia Lyase Activity, Reactive Oxygen Species, and Fusarium Resistance in Selected Species of Wheat with Different Ploidy Levels.

In wheat, resistance to is conditioned by anatomical, morphological, and physiological traits. The aim of this study was to evaluate selected elements of constitutive barriers in common wheat, spelt, Polish wheat, emmer, and einkorn. The activity of the phenylalanine ammonia-lyase (PAL) enzyme and rate of reactive oxygen species (ROS) production were evaluated in the tissues of common wheat and spelt inoculated with .

Correction: Chromosomal distribution of pTa-535, pTa-86, pTa-713, 35S rDNA repetitive sequences in interspecific hexaploid hybrids of common wheat (Triticum aestivum L.) and spelt (Triticum spelta L.).

[This corrects the article DOI: 10.1371/journal.pone.

The Seronegative Spondyloarthropathies.

The seronegative spondyloarthropathies are a group of five diseases characterized by inflammatory oligoarticular arthritis, enthesitis, and axial involvement. They have an increased incidence of the HLA-B27 gene. They are commonly associated with extra-articular features including involvement of the skin, eyes, and gastrointestinal tract.

A Review of the Interactions between Wheat and Wheat Pathogens: Zymoseptoria tritici, Fusarium spp. and Parastagonospora nodorum.

is a hemibiotrophic pathogen which causes Septoria leaf blotch in wheat. The pathogenesis of the disease consists of a biotrophic phase and a necrotrophic phase. The pathogen infects the host plant by suppressing its immune response in the first stage of infection.

Chromosomal distribution of pTa-535, pTa-86, pTa-713, 35S rDNA repetitive sequences in interspecific hexaploid hybrids of common wheat (Triticum aestivum L.) and spelt (Triticum spelta L.).

Fluorescent in situ hybridization (FISH) relies on fluorescent-labeled probes to detect specific DNA sequences in the genome, and it is widely used in cytogenetic analyses. The aim of this study was to determine the karyotype of T. aestivum and T.

Alternaria alternata (Fr.) Keissl with mutation G143A in the Cyt b gene is the source of a difficult-to-control allergen.

The saprotrophic fungus Alternaria alternata is widespread in the agro-environment and produces more than ten allergenic proteins, mostly protein Alt a 1. The frequency of the Alt a 1 gene was analyzed in a group of A. alternata isolates from winter wheat kernels obtained in Poland, and the effectiveness of various fungicides targeting the pathogen was evaluated.

Rare Case of Rapidly Worsening REM Sleep Induced Bradycardia.

Sinoatrial arrest also known as sinus pause occurs when sinoatrial node of the heart transiently ceases to generate the electrical impulse necessary for the myocardium to contract. It may last from 2.0 seconds to several minutes.

Daily supplementation of D-ribose shows no therapeutic benefits in the MHC-I transgenic mouse model of inflammatory myositis.

Background: Current treatments for idiopathic inflammatory myopathies (collectively called myositis) focus on the suppression of an autoimmune inflammatory response within the skeletal muscle. However, it has been observed that there is a poor correlation between the successful suppression of muscle inflammation and an improvement in muscle function. Some evidence in the literature suggests that metabolic abnormalities in the skeletal muscle underlie the weakness that continues despite successful immunosuppression.

Macroparasite population dynamics among geographical localities and host life cycle stages: eugregarines in Ischnura verticalis.

Populations of several species of gregarine parasites within a single host species, the damselfly Ischnura verticalis , were examined over the course of 1 season at 4 geographic localities separated by a maximum distance of 9.7 km. Gregarines, having a life cycle with both exogenous and endogenous stages, are subject to a wide variety of selective pressures that may drive adaptation.

Determinants of disability among the elderly population in a rural south Indian community: the need to study local issues and contexts.

Background: Disability among the elderly is a cause of significant burden. There is dearth of relevant research from low- and middle-income countries. We aimed to establish the nature and factors associated with disability among the elderly in a rural south Indian community.

Solid-state reduction of iron in olivine-planetary and meteoritic evolution.

Iron-nickel metallic particles have been reported in meteorites and lunar and terrestrial rocks. The origin of these metallic particles is not unique as they may be formed by (1) condensation from a primordial solar nebula; (2) crystallization from a melt; and (3) subsolidus reduction reactions under low oxygen or sulphur fugacity. We report here an electron microscopy study of the solid-state microstructural development in olivine single crystals (Fo) in which half of the iron has been reduced to the metallic state by a gas-solid interaction in the temperature range 950-1,500 °C.

Alternative methods for determining the electrical conductivity of core samples.

Electrode configurations are described that can be used in measuring the electrical conductivity of a core sample and that do not require access to the core end faces. The use of these configurations eliminates the need for machining the core ends for placement of end electrodes. This is because the conductivity in the cases described is relatively insensitive to the length of the sample.