Sesquiterpene and acyclic diterpenes from Hyptis verticillata Jacq.

From the methanolic extract of the plant Hyptis verticillata Jacq, was isolated five compounds: the novel compounds cadina-10(15)-en-3-one and 3,7,11,15-tetramethylhexadec-1-en-3-ol and the known compounds 3,7,11,15-tetramethylhexadec-2-en-1-ol, 7,11,15-trimethyl-3-methylenehexadecane-1,2-diol and myo-inositol. All structures were established by spectroscopic means.

Abietane diterpeniods from Hyptis verticillata.

Seven abietane diterpenoids were isolated from the roots of Hyptis verticillata (Labiatae). One is a novel natural product, 7-acetoxy-16-benzoxy-12-hydroxyabieta-8,12-diene-11,14-dione (1), while the other six known compounds are 11,14 dihydroxy-12-methoxyabieta-8,11,13-triene-7-one (2), 11,14-dihydroxy-12-methoxy- 18(4-->3betaH) abeo-abieta-4(19),8,11,13-tetraene-7-one (3), 7-acetoxy-12-methoxyabieta-8,12-diene-11,14-dione (4), royleanone (5), 7,6-dehydroroyleanone (6) and 7-acetoxyhorminone (7). All structures were elucidated by spectroscopic and mass spectrometric means.