The QuantumCor device for treating mitral regurgitation: an animal study.

Objectives: The mitral annular contraction achieved could help reduce mitral regurgitation (MR), and with appropriate modifications, be applied to human subjects providing a potentially effective percutaneous method of valve repair.

Background: MR is an important source of morbidity and is an independent predictor of mortality. A variety of percutaneous approaches are being developed to address this issue.

Collagen mechanics: a rationale for radiofrequency energy to treat mitral regurgitaton.

Despite a variety of pharmacological interventions to limit the regurgitant fraction, mitral regurgitation requires surgical intervention for definitive treatment. New nonsurgical techniques are being applied to treat mitral regurgitation. The mitral and tricuspid annuli are areas of dense collagen.

Percutaneous treatment for mitral regurgitation: the QuantumCor system.

Aims: Percutaneous edge-to-edge techniques and annuloplasty have been used to treat mitral regurgitation (MR). However, neither intervention can be performed reliably a second time and, with annuloplasty, a foreign body is left behind. The mitral and tricuspid annuli are areas of dense collagen (Fig.