Biochemical strategy-based hybrid hydrogel dressing-mediated in situ synthesis of selenoproteins for DFU immunity-microbiota homeostasis regulation.

Chronic consequences of diabetes that are most commonly encountered are diabetic foot ulcers (DFUs), driven by microbiota-immune system dyshomeostasis, eventually leading to delayed wound healing. Available therapies, such as systemic or topical administration of anti-inflammatory or antimicrobial agents, are limited due to antibiotic resistance and immune dysfunction. Herein, a hybrid hydrogel dressing is developed as the artificial bioadhesive barrier at wound sites to maintain microbial and immunological homeostasis locally and have potent anti-inflammatory effects.

A comprehensive pan-cancer analysis revealing the role of ITPRIPL1 as a prognostic and immunological biomarker.

Inositol 1,4,5-Trisphosphate Receptor-Interacting Protein-Like 1 (ITPRIPL1), a single-pass type I membrane protein located in the membrane, functions as an inhibitory ligand of CD3ε. Recent studies have shown that its expression suppresses T cells activation and promote tumor immune evasion. Despite increasing evidence suggesting that ITPRIPL1 plays a significant role in tumor growth, no systematic pan-cancer analysis of ITPRIPL1 has been conducted to date.

A novel mutation in the ATP7B gene causing hepatolenticular degeneration in a Chinese family: A case report.

Introduction: Hepatolenticular degeneration (Wilson disease) is an autosomal recessive monogenic disorder caused by mutations in the ATPase copper transporting beta (ATP7B) gene located on human chromosome 13. This gene encodes a copper-transporting P-type ATPase (ATP7B). Recent studies have revealed that the ATP7B gene is predominantly affected by a few hotspot mutations, with the His1069Gln mutation in exon 14 accounting for 50 to 80% of cases.

One-dimensional HVO nanorods and two-dimensional lamellar MXene composites as efficient cathode materials for aqueous rechargeable zinc ion batteries.

The energy crisis is a the worldwide problem which needs humans to solve immediately. To solve this problem, it is necessary to develop energy storage batteries. It is worth mentioning the aqueous rechargeable zinc ion batteries (ARZBs) which have some advantages, such as low cost, good safety and no need for an organic electrolyte as in the traditional lithium-ion batteries.

Correction: Enhanced charge transport properties of an LFP/C/graphite composite as a cathode material for aqueous rechargeable lithium batteries.

[This corrects the article DOI: 10.1039/D3RA04143C.].

Enhanced charge transport properties of an LFP/C/graphite composite as a cathode material for aqueous rechargeable lithium batteries.

Electrodes that offer quick ion transport, a large surface area, and excellent electrical conductivity support high performance aqueous rechargeable lithium batteries. LiFePO (LFP) nanoparticles have been successfully coated with carbon by a chemical sol-gel route, and assembled on graphite by an ultrasonication method to acquire LFP/C/graphite. This LFP/C/graphite composite exhibits exceptional electrochemical performance at various current densities (1C to 20C).

Research progress of vanadium pentoxide photocatalytic materials.

Photocatalytic reactions convert solar energy into chemical energy through a clean and green reaction process. Photocatalytic technology based on semiconductor materials provides us with a new idea in energy utilization and environmental governance. It was found that vanadium pentoxide (VO) has a narrow band gap, wide response range in the visible region, high oxygen density in the VO lattice, high oxidation state of V, small energy requirement, and superior catalytic activity in partial oxidation.

Fabrication and catalytic properties of nanorod-shaped (Pt-Pd)/CeO composites.

Nanorod-supported (Pt-Pd)/CeO catalysts were synthesized by a simple method of dealloying AlCe Pt Pd ( = 0, 0.075, 0.1, 0.

Synthesis and Electrochemical Performance of KVO/GO Composites as Anodes for Aqueous Rechargeable Lithium-Ion Batteries.

KVO (KVO) and KVO/graphene oxide (KVO/GO) have been successfully synthesized by a chemical coprecipitation method and a subsequent calcination process. The structure and morphology of KVO and KVO/GO were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and X-ray photoelectron spectroscopy. The as-obtained vanadate and vanadate modified by GO materials were used as anodes with LiMnO as a cathode and saturated LiNO as an electrolyte to assemble an aqueous rechargeable lithium-ion battery (ARLB).

Predicting Egg Passage Adaptations to Design Better Vaccines for the H3N2 Influenza Virus.

Seasonal H3N2 influenza evolves rapidly, leading to an extremely poor vaccine efficacy. Substitutions employed during vaccine production using embryonated eggs (i.e.

A hybrid composite of HVO and graphene for aqueous lithium-ion batteries with enhanced electrochemical performance.

Aqueous rechargeable lithium-ion batteries (ARLBs) are regarded as a competitive challenger for large-scale energy storage systems because of their high safety, modest cost, and green nature. A kind of modified composite material composed of HVO nanorods and graphene sheets (HVO/G) has been effectively made by a one-step hydrothermal method and following calcination at 523 K. XRD, SEM, TEM, and TG are used to determine the phase structures and morphologies of the composite materials.

Revision of the genus Adiscus Gistel, 1857 (Coleoptera: Chrysomelidae, Cryptocephalinae) from mainland China.

The mainland Chinese fauna of the leaf beetle genus Adiscus Gistel, 1857 is revised and three new species described: Adiscus daofuensis Duan Zhou, new species from Sichuan, Gansu and Henan, A. ningshanensis Duan Zhou, new species from Shaanxi, and A. tanae Duan Zhou, new species from Tibet.

Two new species of the genus Chevrolat, 1836 (Coleoptera, Chrysomelidae, Cryptocephalinae) from China.

Two new species of the genus Chevrolat from China are reported: Duan, Wang & Zhou from Xinjiang, and Duan, Wang and Zhou from Yunnan. Six species, (Jacoby), Medvedev, Lopatin, (Pic), Kimoto & Gressitt, and Medvedev are new country records for China. Color illustrations and line drawings of general habitus and morphological details are given.

Two new species of the genus Suffrian (Coleoptera, Chrysomelidae, Cryptocephalinae) from China.

Two new species of the genus Suffrian, 1854 are described from China: Duan, Wang & Zhou, from Yunnan (also in Vietnam, Tonkin) and Duan, Wang & Zhou, from Yunnan. Another species, Pic, 1926, is reported for the first time in China. High-quality color images and line drawings of adult habitus, aedeagus, and other important structures are provided for all three species.

Novel Dealloying-Fabricated NiS/NiO Nanoparticles with Superior Cycling Stability for Supercapacitors.

NiS/NiO nanoparticles are successfully fabricated through a simple dealloying method and an ion-exchange process. X-ray diffraction demonstrates the existence of NiO and NiS phases, and scanning electron microscopy and transmission electron microscopy imply the nanopore distribution nature and the nanoparticle morphology of the produced material. The electrochemical behaviors are studied by cyclic voltammetry and galvanostatic charge-discharge measurements.

De novo TCOF1 mutation in Treacher Collins syndrome.

Objective: To analyze the genetic cause of a hearing loss child with the Treacher Collins syndrome (TCS) phenotypes of malar hypoplasia, micrognathia, antimongoloid slanting palpebral fissures and cup ears.

Methods: Clinical analysis, hearing tests, chromosomal microarray analysis (CMA) and whole exome sequencing (WES) were performed on the family members.

Results: The 6 months old boy with a range of Treacher Collins syndrome phenotypes including malar hypoplasia, micrognathia, antimongoloid slanting palpebral fissures, cup ears, and hearing loss.

Using Composite Phenotypes to Reveal Hidden Physiological Heterogeneity in High-Altitude Acclimatization in a Chinese Han Longitudinal Cohort.

Altitude acclimatization is a human physiological process of adjusting to the decreased oxygen availability. Since several physiological processes are involved and their correlations are complicated, the analyses of single traits are insufficient in revealing the complex mechanism of high-altitude acclimatization. In this study, we examined these physiological responses as the composite phenotypes that are represented by a linear combination of physiological traits.

Wiedemann-steiner syndrome with a de novo mutation in KMT2A: A case report.

Rationale: Wiedemann-Steiner syndrome (WDSTS, online mendelian inheritance in man 605130) is a rare autosomal dominant disorder characterized by hypertrichosis cubiti. Here, we report a Chinese boy who do not show the characteristic of hypertrichosis cubiti, and was misdiagnosed as blepharophimosis-ptosis-epicanthus inversus syndrome at first. We found a de novo frameshift mutation (p.

Superior electrochemical performance of a novel LiFePO/C/CNTs composite for aqueous rechargeable lithium-ion batteries.

Olivine LiFePO covered flocculent carbon layers wrapped with carbon nanotubes (CNTs) prepared by sol-gel method and calcination is used as the cathode material for aqueous rechargeable lithium-ion batteries (ARLBs). The phase structures and morphologies of the composite material are characterized by X-ray diffraction (XRD), selected area electron diffraction (SAED), and transmission electron microscopy (TEM). The mechanism and method through which CNTs and flocculent carbon improve the electrochemical performance are investigated in an aqueous lithium-ion battery by setting up a comparative experiment.

Superior cycling performance of a novel NKVO@polypyrrole composite anode for aqueous rechargeable lithium-ion batteries.

An aqueous rechargeable lithium-ion battery (ARLB) system has been assembled using as-prepared polypyrrole (PPy) to coat NaKKO (NKVO) anode coupled with LiMnO cathode, both immersed in an aqueous LiNO solution. The chemical polymerization techniques have been employed to uniformly coat the surface of NKVO with PPy. The phase of NKVO@PPy composite has been characterized by X-ray diffraction; for quantifying PPy content, the thermal gravimetric analysis was performed.

Synthesis and evaluation of the SERS effect of FeO-Ag Janus composite materials for separable, highly sensitive substrates.

FeO-Ag Janus composites were synthesized using a two-step solvothermal method. The optimal growth process was determined by investigating the relationship between the particle morphologies and reaction time. Magnetic and Raman spectroscopic measurements showed that the as-synthesized Janus composites have both good magnetic response and significant surface-enhanced Raman scattering (SERS) effects, as well as reproducibility.

[Mutation analysis for a family affected with von Hippel-Lindau syndrome].

Objective: To detect VHL gene mutation in a pedigree affected with von Hippel-Lindau syndrome (VHL).

Methods: Clinical data of the pedigree was reviewed. Patients were subjected to Sanger sequencing to detect mutation of the VHL gene.

Susceptibility to congenital heart defects associated with a polymorphism in TBX2 3' untranslated region in the Han Chinese population.

Background: Tbx2 plays a critical role in determining fates of cardiomyocytes. Little is known about the contribution of TBX2 3' untranslated region (UTR) variants to the risk of congenital heart defect (CHD). Thus, we aimed to determine the association of single-nucleotide polymorphisms (SNPs) in TBX2 3' UTR with CHD susceptibility.

Superior lithium-ion insertion/extraction properties of a novel LiFePO/C/graphene material used as a cathode in aqueous solution.

Herein, olivine LiFePO covered with graphene and carbon layers is prepared via a sol-gel method, followed by calcination, and the resultant composite is used as a cathode material in aqueous rechargeable lithium-ion batteries (ARLBs). The phase structure and morphology of the composite are characterized via X-ray diffraction (XRD), transmission electron microscopy (TEM), high-resolution transmission electron microscopy (HRTEM) and specific surface area analysis (BET). The ARLB system is fabricated using LiFePO/C/graphene as the cathode and a zinc anode in 1 mol L ZnSO·7HO and saturated LiNO aqueous solution without dissolved oxygen, which delivers a capacity of 153 mA h g at 0.