Effects of residual black fruit on growth performance, rumen fermentation parameters, microflora and economic benefits of fattening sheep.

Introduction: The residual black wolfberry fruit (RBWF) is rich in nutrients and contains a diverse range of active substances, which may offer a viable alternative to antibiotics. This experiment was conducted to investigate the impact of varying levels of RBWF on the growth performance and rumen microorganisms of fattening sheep, and to quantify its economic benefits.

Methods: In this experiment, 40 three-month-old and male Duolang sheep with an average weight of 29.

DNA Methylation and Transcriptome Profiling Reveal the Role of the Antioxidant Pathway and Lipid Metabolism in Skin Color Formation.

Leopard coral grouper (), possessing a distinct red body color, is an important species in commercial markets; however, the high ratio of black individuals under intensive cultivation has limited the commercial value of the species. To dissect the regulatory mechanisms underlying the red skin trait in , gene expression and DNA methylation modifications were compared between red and black skin tissues after astaxanthin treatment. Astaxanthin effectively increased the redness value a* and body weight.

Regulating Charge Distribution in Porphyrin-Based Polymer for Achieving Photocatalytic CO Conversion to CH or CH.

The photocatalytic conversion of CO into products such as CH and CH poses a significant challenge due to the lengthy reaction steps and the high energy barrier involved. In this study, both benzothiadiazole (BTD) and hydroxyl groups (-OH) are introduced into cobalt-based polymerized porphyrinic network (PPN) through a C-C coupling reaction. This modification of orbital energy levels that strengthens the ability of gain electrons and facilitates the charge transfer in PPN.

Cystoscope-free ureteral stent removal: a safe and effective method during the COVID-19 pandemic.

Ureteral stent must be removed within a certain period, usually performed under the cystoscope. However, cystoscopic operations procedures carry risks such as urethral injury, hemorrhage, and infection. This study aimed to implement a cystoscope-free method for ureteral stent removal during the COVID-19 pandemic to mitigate the complications associated with cystoscopy, reduce the risk of cross-infection, and conserve medical resources and time.

Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg2.

Aims: Magnesium ions (Mg) play an important role in promoting cartilage repair in cartilage lesions. However, no research has focused on the role of Mg combined with microfracture (MFX) in hyaline-like cartilage repair mediated by cartilage injury. This study aimed to investigate the beneficial effects of the combination of MFX and Mg in cartilage repair.

Validation Status of Electronic Sphygmomanometers in China: A National Survey.

Background: Although the information on the validation status of electronic sphygmomanometer (ES) devices in use in health care institutions and households is much more clinically relevant than that of ES models available on the market, it remains insufficient.

Methods: A national survey was conducted across all administrative regions of mainland China to assess the validation status of ESs. Fifty-eight cities were selected with stratification by municipality, provincial capital, and other cities, and health care institutions and households in each city were chosen by convenience to identify ES devices in use according to the study protocol.

Phosphorescent Liquid Crystalline Polymer-based Circularly Polarized Luminescence Optical Waveguides for Enhanced Photonic Signal Processing and Information Encryption.

Efficient circularly polarized luminescence (CPL) optical waveguides have significant potential for advancing photonic and optoelectronic devices. However, the development of CPL optical waveguides materials (OWMs) with low optical loss coefficient remains a considerable challenge. To overcome this, we design and synthesize CPL OWMs based on room-temperature phosphorescent liquid crystalline polymers (LCPs).

Cross-Lagged Panel Network Analysis of Symptoms in Patients with Gastric Cancer Undergoing Postoperative Chemotherapy.

Objectives: To develop temporal symptom networks at three postoperative chemotherapy time points and investigate the longitudinal relationships between 18 symptoms in patients with gastric cancer undergoing postoperative chemotherapy in China.

Methods: Symptom prevalence and severity were measured using the M. D.

Pseudo-Phosphorylated Tau Forms Paired Helical Filaments in the Presence of High-Curvature Cholesterol-Containing Lipid Membranes.

The tau protein misfolds in neurodegenerative diseases such as Alzheimer's disease (AD). These pathological tau aggregates are associated with neuronal membranes, but molecular structural information about how disease-like tau fibrils interact with the lipid membrane is scarce. Here, we use solid-state NMR to investigate the structure of a tau construct bearing four AD-relevant phospho-mimetic mutations (4E tau) with cholesterol-containing high-curvature lipid membranes, which mimic the membrane of synaptic vesicles in neurons.

Determination of the Minimum Uncut Chip Thickness of Ti-6Al-4V Titanium Alloy Based on Dead Metal Zone.

In Ti-6Al-4V titanium alloy micro-machining, since the uncut chip thickness (UCT) is comparable to the radius of the tool cutting edge, there exists a minimum uncut chip thickness (MUCT), and when the UCT is smaller than the MUCT, the plowing effect dominates the cutting process, which seriously affects the machined surface quality and tool life. Therefore, the reliable prediction of the MUCT is of great significance. This paper used Deform to establish an orthogonal cutting simulation model, studied the effect of the dead metal zone (DMZ) on the micro-cutting material flow, determined the DMZ range, and proposed a new method for determining the MUCT based on the DMZ.

GYY4137 ameliorates blood brain barrier damage by inhibiting autophagy mediated occludin degradation in cardiac arrest and resuscitation.

Cardiopulmonary resuscitation (CPR) after cardiac arrest (CA) is an important cause of neurological impairment and leads to considerable morbidity and mortality. The stability of the blood-brain barrier (BBB) is crucial for minimizing secondary neurological damage and improving long-term prognosis. However, the precise mechanisms and regulatory pathways that contribute to BBB dysfunction after CPR remain elusive.

Understanding the Dynamic Evolution of Active Sites among Single Atoms, Clusters, and Nanoparticles.

Catalysis remains a cornerstone of chemical research, with the active sites of catalysts being crucial for their functionality. Identifying active sites, particularly during the reaction process, is crucial for elucidating the relationship between a catalyst's structure and its catalytic property. However, the dynamic evolution of active sites within heterogeneous metal catalysts presents a substantial challenge for accurately pinpointing the real active sites.

Nano-island-encapsulated cobalt single-atom catalysts for breaking activity-stability trade-off in Fenton-like reactions.

Single-atom catalysts (SACs) have been increasingly acknowledged for their performance in sustainable Fenton-like catalysis. However, SACs face a trade-off between activity and stability in peroxymonosulfate (PMS)-based systems. Herein, we design a nano-island encapsulated single cobalt atom (Co-ZnO) catalyst to enhance the activity and stability of PMS activation for contaminant degradation via an "island-sea" synergistic effect.

Moisture-based green energy harvesting over 600 hours via photocatalysis-enhanced hydrovoltaic effect.

Harvesting the energy from the interaction between hygroscopic materials and atmospheric water can generate green and clean energy. However, the ion diffusion process of moisture-induced dissociation leads to the disappearance of the ion concentration gradient gradually, and there is still a lack of moisture-based power generation devices with truly continuous operation, especially the duration of the current output still needs to be extended. Here, we propose a design for reconstructing the ion concentration gradient by coupling photocatalytic hydrogen evolution reaction with hydrovoltaic effect, to report a moisture-enabled electric generator (MEG) with continuous current output.

Enhanced peroxone reaction with amphoteric oxide modulation for efficient decontamination of challenging wastewaters: Comparative performance, economic evaluation, and pilot-scale implementation.

The peroxone reaction, a promising alternative technology for water treatment, is traditionally hampered by its restricted pH operational range and suboptimal oxidant utilization. In this study, we introduced a novel amphoteric metal oxide (ZnO)-regulated peroxone system that transcended the pH limitations of conventional peroxone processes. Our innovative approach exploited the unique properties of ZnO to regulate the reaction pathway of the traditional O/HO (or peroxymonosulfate, PMS) processes, resulting in a 52.

Dual-objective optimization of prefabricated component logistics based on JIT strategy.

Prefabricated construction involves manufacturing components in a factory and then transporting them to a construction site for assembly, yielding resource savings and improved efficiency. However, the large size and weight of prefabricated components, along with strict delivery requirements, introduce logistical challenges, such as increased carbon emissions during transport and site congestion. This study addresses the dual-objective vehicle scheduling problem for prefabricated components.

Individual FiO guided by SO prevents hyperoxia and reduces postoperative atelectasis in colorectal surgery: A randomized controlled trial.

Study Objective: To determine whether individualized fraction of inspired oxygen (iFiO) improves pulmonary atelectasis after elective laparoscopic colorectal surgery relative to 60 % FiO.

Design: This was a single-center, prospective, randomized study.

Setting: This study was conducted in a single tertiary care hospital in China.

[Plant Growth-promoting Bacteria Alleviate the Toxic Effects of Soil Microplastics and Heavy Metal Complex Pollution in ].

The coexistence of microplastics and heavy metals in soil can lead to more intricate environmental effects. While plant growth-promoting bacteria have been widely recognized for enhancing the remediation of heavy metal-contaminated soils, little research has been conducted to investigate whether they can alleviate the stress of microplastic-heavy metal composite contamination on plants. We investigated the effects of isolated and screened plant growth-promoting bacteria on the growth and cadmium （Cd） accumulation of under the composite pollution of Cd and polypropylene （PP） with different particle sizes （6.

Latent profile analysis of spousal information concealment in patients with cancer: A cross-sectional study.

Objective: This study aimed to investigate spousal information concealment in patients with cancer and analyse its influencing factors.

Methods: Between April and July 2024, 371 spouses of patients with cancer were surveyed using the Demographic and Clinical Characteristics Questionnaire, the Information Concealment Scale for Caregivers, Fear of Progression Questionnaires for Partners, and the Medical Coping Modes Questionnaire. Influencing factors were analysed using latent profile analysis.

SPECTRAL BRAIN GRAPH NEURAL NETWORK FOR PREDICTION OF ANXIETY IN CHILDREN WITH AUTISM SPECTRUM DISORDER.

Children with Autism Spectrum Disorder (ASD) frequently exhibit comorbid anxiety, which contributes to impairment and requires treatment. Therefore, it is critical to investigate co-occurring autism and anxiety with functional imaging tools to understand the brain mechanisms of this comorbidity. Multidimensional Anxiety Scale for Children, 2nd edition (MASC-2) score is a common tool to evaluate the daily anxiety level in autistic children.

Controllable Self-Assembly of V═O Metalloradical Complex with Intramolecular Charge Transfer for Enhanced NIR-II Fluorescence Imaging-Guided Photothermal Therapy.

Near-infrared second region (NIR-II) fluorescence imaging provides enhanced tissue penetration, achieving efficient NIR-II fluorescence and photoacoustic imaging (PA)-guided photothermal therapy (PTT) all in one material remains a challenging yet promising approach in cancer treatment. Herein, open-shell V═O metalloradical complex (VONc) is self-assembled into VONc nanospheres (VONc NPs). VONc NPs exhibit light absorption from 300 to 1400 nm, fluorescence spectra ranging from 900 to 1400 nm, and a distinct fluorescence signal even at 1550 nm.

Evaluating Blended Teaching Models in Medical Colleges: Preferences and Influential Factors for Teachers and Students.

Objective: This study evaluates the adoption of blended teaching models by faculty and students at Hubei University of Medicine. It aims to assess their willingness to adopt hybrid learning and identify the factors influencing their choices. The goal is to provide a theoretical foundation for reforming teaching models.

Structure-activity relationship and in silico docking analysis of dicarboximide fungicides on 17β-hydroxysteroid dehydrogenase 1 of human, rat, and pig.

Dicarboximide fungicides, including captafol, captan, cyclohexylthiophthalimide, folpet, and procymidone, represent a distinct category of fungicides. 17β-Hydroxysteroid dehydrogenase 1 (17β-HSD1) catalyzes the conversion of estrone to estradiol in mammals. Yet, the impact of these fungicides on 17β-HSD1 activity remains unknown.

Redox potentials of sulfonamide antibiotics mediating the electron transfer process in single-atom Cu catalyst/peroxymonosulfate system: Selective removal mechanisms for sulfonamides.

The oxidative behaviors of target pollutants in single-atom catalysts-activated peroxymonosulfate (SACs/PMS) system has mostly been studied from the loaded metal and coordination structure of SACs. However, the origin of the altered degradation behavior caused by the specific properties of pollutants has been neglected. Herein, Cu atoms coordinated with four N atoms embedded in biochar (Cu@C) was prepared to establish the relationship between the selective degradation behavior of sulfonamide antibiotics in Cu@C/PMS system and their own properties.

Silencing CaPIP5K4-1 leads to decreased male fertility in Capsicum annuum L.

Phosphatidylinositol 4-phosphate 5-kinase gene CaPIP5K4-1 is highly expressed in the pepper anthers. Virus-induced gene silencing of CaPIP5K4-1 leads to reduced male fertility in pepper. The phosphatidylinositol 4-phosphate 5-kinase (PIP5K) is a pivotal enzyme in the phosphatidylinositol signaling pathway, and its crucial involvement in both plant development and stress response has been established.