Differential expression and function of survivin during the progress of pterygium.

Purpose: To investigate the expression pattern and function of survivin in the development of pterygium.

Methods: Primary pterygia at quiescent or advanced clinical stage and normal human conjunctival tissues were used in this study. Pterygium epithelial cells (PECs) were cultured in keratinocyte serum-free defined medium and harvested at different growth stages.