Publications by authors named "Du-Bo Chen"
Article Synopsis
- The paper examines the effectiveness of using chemotherapy along with CD19 and CD20 monoclonal antibodies to treat minimal residual disease (MRD) in children with refractory acute B-lymphoblastic leukemia (B-ALL) and discusses relevant research.
- A 4-year-old boy with B-ALL was treated according to the SCCLG-ALL-2016 protocol but initially had persistent MRD until he was given a combination of consolidation chemotherapy and monoclonal antibodies, leading to a negative MRD result and successful stem cell transplantation.
- The study concludes that this treatment approach significantly improves remission rates in refractory B-ALL, showing no adverse effects and suggesting its potential as a viable treatment option for these patients.
Noninvasive tools for the prognosis of colorectal cancer (CRC) are in urgent need. Lipids and proteins have been studied in CRC several years, thus a prognostic indicator based on preoperative serum high-density lipoprotein cholesterol (HDL-C) and serum albumin (ALB) levels (HA score) in CRC patients and to compare the correlation with survival to that of the Glasgow prognostic score. In the present study, the patient characteristics, clinicopathological factors, and the level of pre-treatment serum markers (HDL-C, ALB, CEA and CA19-9) were analyzed retrospectively in 248 patients with CRC.
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