Publications by authors named "Du Ran"

Horizontal arrays of single-walled carbon nanotubes (SWCNTs) have shown immense potential for application in emerging devices due to their excellent electrical and thermal properties. The direct growth of SWCNT arrays using high-activity metal catalysts is one of the promising methods to approach the mass production of dense SWCNT arrays. However, an inevitable obstacle lies in the post-purification of metal residual.

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In tomato, sugar content is highly correlated with consumer preferences, with most consumers preferring sweeter fruit. However, the sugar content of commercial varieties is generally low, as it is inversely correlated with fruit size, and growers prioritize yield over flavour quality. Here we identified two genes, tomato (Solanum lycopersicum) calcium-dependent protein kinase 27 (SlCDPK27; also known as SlCPK27) and its paralogue SlCDPK26, that control fruit sugar content.

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Plant pathogenic fungi pose a substantial challenge to agricultural production, but the conventional fungicide-based approaches are losing importance. As agents with broad-spectrum antibacterial effects, gold nanoparticles (Au NPs) are found to have antifungal effects; however, no study has examined their application in agriculture as fungicides. Accordingly, this study investigates the activity of 2-mercaptoimidazole-capped Au NPs (MI-Au NPs) against the 'top' plant pathogenic fungi, finding that they could inhibit , , and by inducing cytoplasmic leakage.

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Objectives: We investigate the impact of wildfire disasters on cognitive health (i.e., thinking and language skills) in individuals aged 10 years and older using 2014 and 2018 wildfire and cognitive ability survey data from China.

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Background: The objective of this study was to investigate the value of mismatch negativity (MMN) and P300 event-related potentials for discriminating the consciousness state and predicting improvement of consciousness at 6 months in patients with coma and other disorders of consciousness (DOC).

Methods: We performed MMN and P300 on 42 patients with DOC with a mean onset time of 40.21 ± 19.

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Article Synopsis
  • - The study introduces a new passive radiative cooling technology using a polyimide/zinc oxide composite membrane that effectively reflects sunlight and emits infrared heat, achieving significant cooling without electricity.
  • - The membrane demonstrates impressive performance with a 91.4% sunlight reflectance and a temperature drop of around 9.3°C under direct sun, while maintaining effectiveness even after being heated to 200°C.
  • - This innovative material is not only efficient in cooling, but also shows high resistance to UV exposure and outdoor contamination, making it suitable for practical use in challenging environments.
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Chronic kidney disease (CKD) poses a significant global health dilemma, emerging from complex causes. Although our prior research has indicated that a deficiency in Reticulon-3 (RTN3) accelerates renal disease progression, a thorough examination of RTN3 on kidney function and pathology remains underexplored. To address this critical need, we generated Rtn3-null mice to study the consequences of RTN3 protein deficiency on CKD.

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Under the influence of multiple uncertain factors at home and abroad, urban amenities, as the underlying support for urban renewal activities, are of great significance in enhancing urban economic resilience. The panel data of Chinese cities from 2011 to 2019 is used in this study. Urban amenity is measured from artificial amenities and climate amenities, respectively.

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Abnormal secretion and dysrhythmias of cortisol (CORT) are associated with various diseases such as sleep disorders, depression, and chronic fatigue. Wearable devices are a cutting-edge technology for point-of-care detection and dynamic monitoring of CORT with inspiring convenience. Herein, we developed a minimally invasive skin-worn device with the advanced integration of both interstitial fluid (ISF) sampling and target molecule sensing for simultaneous detection of CORT via a microneedle-based sensor with high sensitivity, excellent efficiency, and outstanding reproducibility.

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Objective: This study presents a detailed analysis of the clinical and genetic characteristics of uterine leiomyoma associated with Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC), combined with exploration of family history, pathology, and management procedures, supported by thorough evidence collection.

Methods: Blood samples were collected from the proband, and the pathogenic variant was verified using Sanger sequencing. A comprehensive review of family history, FH deficiency pathology, FH and 2SC immunohistochemistry staining was conducted.

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Article Synopsis
  • Acute myocardial infarction (AMI) is primarily caused by the rupture of unstable coronary plaques, leading to a series of damaging biological events culminating in heart cell death.
  • This study analyzed gene expression data related to AMI, focusing on the role of platelet-derived microvesicles (PMVs) and identified a specific miRNA-mRNA regulatory network involving the gene ACSL1.
  • It was found that high ACSL1 levels in AMI patients' platelets could promote heart cell death through PMV transport, suggesting potential therapeutic strategies to protect heart cells from Ferroptosis in AMI patients.
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Background: Chronic kidney disease (CKD) patients have been found to be at risk of concurrent cognitive dysfunction in previous studies, which has now become an important public health issue of widespread concern.

Aim: To investigate the risk factors for concurrent cognitive dysfunction in patients with CKD.

Methods: This is a prospective cohort study conducted among patients with CKD between October 2021 and March 2023.

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Exploring anticorrosion electromagnetic wave (EMW) absorbing materials in harsh conditions remains a challenge. Herein, S-NiSe/HG nanocomposites encapsulated in room-temperature self-healing polyurethane (S-NiSe/HG/SPU) were exploited as superior anticorrosion EMW absorbing materials. A dual-defect engineering collaborative Schottky interface construction endows S-NiSe/HG with a high vacancy concentration, abundant defects, and moderate conductivity.

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Article Synopsis
  • Tracking nitrogen pollution sources is essential for managing water quality but is complicated due to varied contamination scenarios in freshwater systems.
  • In this study, the Soil and Water Assessment Tool (SWAT) and a pollution source database were used to classify sub-basins of the Liuyang River watershed based on their main nitrogen pollution sources.
  • A Random Forest model was developed to predict pollution sources using various data types, with the best accuracy achieved by combining taxonomic and functional metagenomic data, highlighting key bacterial species as important indicators of pollution.
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Reticulum 3 (RTN3) is an endoplasmic reticulum (ER) protein that has been reported to act in neurodegenerative diseases and lipid metabolism. However, the role of RTN3 in acute kidney injury (AKI) has not been explored. Here, we employed public datasets, patient data, and animal models to explore the role of RTN3 in AKI.

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Paclitaxel is a well known anticancer compound. Its biosynthesis involves the formation of a highly functionalized diterpenoid core skeleton (baccatin III) and the subsequent assembly of a phenylisoserinoyl side chain. Despite intensive investigation for half a century, the complete biosynthetic pathway of baccatin III remains unknown.

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Objective: To study the influence of the initial partial pressure of carbon dioxide (PaCO) and frequency of blood gas analyses on the positivity rate and safety of apnea testing (AT).

Design: A prospective multicenter cohort study.

Setting: Seven teaching hospitals.

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Importance: High myopia is a global concern due to its escalating prevalence and the potential risk of severe visual impairment caused by pathologic myopia. Using artificial intelligence to estimate future visual acuity (VA) could help clinicians to identify and monitor patients with a high risk of vision reduction in advance.

Objective: To develop machine learning models to predict VA at 3 and 5 years in patients with high myopia.

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Intestinal metabolism-related diseases, such as constipation, inflammatory bowel disease, irritable bowel syndrome, and colorectal cancer, could be associated with the dysfunction of intestinal mitochondria. The mitochondria of intestinal epithelial cells are of great significance for promoting intestinal motility and maintaining intestinal metabolism. It is necessary for the prophylaxis and therapy of intestinal metabolism-related diseases to improve mitochondrial function.

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Tumor-associated macrophages (TAMs) are key components of tumor immune microenvironment and play a dual role in promoting tumor growth and anti-tumor immunity. Therefore, regulating TAMs has become a promising method in cancer immunotherapy. NF- κB pathway is the key regulatory pathway of TAMs.

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Based on 2010-2019 Chinese logistics listed companies as research samples, the paper used the binary Logit model measuring degree of financing constraints. The Kernel density function and Markov chain model are used to forecast China listed companies financing logistics dynamic constraints and business performance growth. Furthermore the stock of knowledge was chosen as a threshold variable to explore the impact of financing constraints on corporate performance growth of listed logistics enterprises.

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Metal aerogels (MAs) are emerging porous materials displaying unprecedented potential in catalysis, sensing, plasmonic technologies, etc. However, the lack of efficient regulation of their nano-building blocks (NBBs) remains a big hurdle that hampers the in-depth investigation and performance enhancement. Here, by harmonizing composition and ligand effects, Pt- and Bi-based single- and bimetallic aerogels bearing NBBs of controlled dimensions and shapes are obtained by facilely tuning the metal precursors and the applied ligands.

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Background: High myopia (HM), defined as a spherical equivalent refractive error (SER) ≤ -6.00 diopters (D), is a leading cause of sight impairment, through myopic macular degeneration (MMD). We aimed to derive an improved polygenic score (PGS) for predicting children at risk of HM and to test if a PGS is predictive of MMD after accounting for SER.

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There is a general increase in the number of patients with non-healing skin wounds, imposing a huge social and economic burden on patients and healthcare systems. Severe skin injury is an important clinical challenge. There is a lack of skin donors, and skin defects and scarring after surgery can lead to impaired skin function and skin integrity.

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