Circularly Polarized Luminescence in Cellulose-Based Assemblies: Synthesis, Regulation, and Application.

Currently, circularly polarized luminescence (CPL) has drawn wide interest in 3D display, information storage, and optical sensing. However, traditional synthetic paths are often accompanied by low chiral optical intensity and complex processes. Cellulose nanocrystals (CNCs), with the properties of liquid crystals, can spontaneously arrange into the left-handed layered nanofilm, which enables them candidates in the construction of CPL materials.

A coaxial 3D bioprinted hybrid vascular scaffold based on decellularized extracellular matrix/nano clay/sodium alginate bioink.

Currently, vascular grafting is the preferred option to replace or bypass the defective vascular segments, but finding materials with good biocompatibility and diversity alternative for practical clinical applications are still the challenge. The construction of tissue engineered blood vessels (TEBVs) with complex structures will be realized using 3D bioprinting technology, which provides a new idea for vascular transplantation. In this paper, the decellularized extracellular matrix (dECM)/nano clay (NC)/sodium alginate (SA) hybrid bioink was prepared to construct tubular scaffolds in vitro by coaxial 3D bioprinting.

Single-cell transcriptomics reveal the prognostic roles of epithelial and T cells and DNA methylation-based prognostic models in pancreatic cancer.

Background: Pancreatic adenocarcinoma (PDAC) exhibits a complex microenvironment with diverse cell populations influencing patient prognosis. Single-cell RNA sequencing (scRNA-seq) was used to identify prognosis-related cell types, and DNA methylation (DNAm)-based models were developed to predict outcomes based on their cellular characteristics.

Methods: We integrated scRNA-seq, bulk data, and clinical information to identify key cell populations associated with prognosis.

Characteristics of corneal aberration in patients with bilateral keratoconus and unilateral corneal Vogt's striae.

Aim: To assess the corneal high-order aberration (HOA) and its correlation with corneal morphological parameters in patients with bilateral keratoconus (KCN) and unilateral Vogt's striae.

Methods: A total of 168 eyes of 84 patients with KCN, whose corneas had definite signs of unilateral Vogt's striae, were enrolled. Corneal HOA and morphological parameters were measured using Pentacam HR.

Effects of preimplantation genetic testing for aneuploidy on embryo transfer outcomes in women of advanced reproductive age with no more than three retrieved oocytes.

Objective: To evaluate whether preimplantation genetic testing for aneuploidy (PGT-A) benefits women of advanced reproductive age (≥38 years old) with a diminished ovarian reserve (DOR; not more than three retrieved oocytes).

Design: A retrospective analysis comparing two groups: (a) PGT-A group: women who chose PGT-A and subsequent single re-warmed embryo transfers (ETs) and (b) non-PGT-A group: women who chose not to genetically test their embryos and underwent subsequent fresh or re-warmed ETs of one to two embryos on days 3 or 5.

Subjects: Two hundred and thirty patients underwent PGT-A therapy, with 49 of these individuals undergoing more than one PGT-A cycle.

Doping Ti into RuO to Accelerate Bridged-Oxygen-Assisted Deprotonation for Acidic Oxygen Evolution Reaction.

The development of efficient and durable electrocatalysts for the acidic oxygen evolution reaction (OER) is essential for advancing renewable hydrogen energy technology. However, the slow deprotonation kinetics of oxo-intermediates, involving the four proton-coupled electron steps, hinder the acidic OER progress. Herein, a RuTiO solid solution electrocatalyst is investigated, which features bridged oxygen (O) sites that act as proton acceptors, accelerating the deprotonation of oxo-intermediates.

Brain functional connectivity under teleoperation latency: a fNIRS study.

Introduction: Long-distance robot teleoperation faces high latencies that pose cognitive challenges to human operators. Latency between command, execution, and feedback in teleoperation can impair performance and affect operators' mental state. The neural underpinnings of these effects are not well understood.

Long-Read Sequencing Revealing the Effectiveness of Captive Breeding Strategy for Improving the Gut Microbiota of Spotted Seal (Phoca largha).

The spotted seal (Phoca largha) is the sole pinniped species that can reproduce in China and has been classified as the First-Grade State Protection animal. The conventional method for the protection and maintenance of the spotted seal population is the captive maintenance of the species in artificially controlled environments. Nevertheless, the efficacy of the captive strategy remains uncertain, with the potential to impact the health of spotted seals through alterations in gut microbiota.

The association of rotator cuff muscle morphology and glenoid morphology in primary glenohumeral osteoarthritis.

Background: This retrospective study investigated associations of rotator cuff muscle atrophy (MA) and fatty infiltration (FI) with glenoid morphology.

Methods: Patients with primary glenohumeral osteoarthritis who presented to Penn State Bone and Joint Institute's orthopaedic clinic from September 2002 to December 2019 as total shoulder arthroplasty (TSA) candidates were evaluated. MA was determined by the cross-sectional area of each rotator cuff muscle on pre-operative MR and CT scans.

Pollution characteristics and health risk assessment of heavy metals in PM2.5 in Fuxin, China.

Fuxin is located in the atmospheric channel around Bohai Bay, and its geographical location is very special. Few existing studies have investigated the pollution characteristics and health risk assessment of heavy metals in atmospheric PM during the four seasons in Fuxin, so a total of 180 PM samples were collected from four sampling sites in Fuxin from December 2021 to November 2022. The seasonal distribution characteristics of V, Cr, Mn, Co, Ni, Cu, Zn, Pb, As, Sb, Cd and Ba were analysed via inductively coupled plasma-mass spectrometry (ICP‒MS), and the source of the heavy metals was analysed via the enrichment factor (EF) and principal component analysis (PCA).

Ignoring the food route underestimated human health risk from potentially toxic elements in agricultural environments of Ziyang, Shaanxi, China.

Staple food is a crucial exposure route for the human intake of potentially toxic elements (PTEs), but it has been neglected in previous human health risk (HHR) studies. Lack of attention to this issue will lead to an underestimation of HHR caused by PTEs. This study establishes a comprehensive regional identification method for health risk assessment (HRA), namely, soil-maize health risk assessment (SMHRA) and applies it to Ziyang, Shaanxi, which is a typical agricultural county.

Effect of legume proteins on the structure and digestibility of wheat starch-lauric acid complexes.

The effect of legume proteins (soy protein (SP), chickpea protein (CP) and peanut protein (PP)) on the properties of wheat starch-lauric acid (WS-LA) system and its intrinsic mechanism were investigated. RVA, digestion experiment and TGA results showed that legume proteins prompted the viscosity peak formation during cooling stage and increased anti-digestion and thermal stability of WS-LA system. FT-IR, Raman, XRD and C NMR results indicated that legume proteins improved the long-range and short-range ordering degree and single-helix structure of WS-LA system.

Associations between nutrition literacy and possible sarcopenia among older adults in Bengbu, China.

To explore the associations between nutrition literacy (NL) and possible sarcopenia in older Chinese adults. A cross-sectional study was conducted. NL was assessed using a twelve-item short-form NL scale.

A uniform-unsaturated crosslinking strategy to construct injectable alginate hydrogel.

The controllable crosslinking between the constituting building blocks plays a key role in endowing the hydrogel with injectability through the formation of a uniform 3D interconnected network. Herein, a uniform-unsaturated crosslinking strategy has been devised to quickly construct injectable sodium alginate (SA) hydrogels. Under vigorous stirring, a moderate amount of metal ions can uniformly coordinate with the guluronate moieties of SA molecules, avoiding the locally excessive crosslinking and the loss of injectability caused by traditional dropping and soaking methods.

Sappanone A ameliorates acute lung injury through inhibiting the activation of the NF-κB signaling pathway.

Acute lung injury (ALI) is a serious respiratory disease characterized by diffuse alveolar injury, and it has emerged as a major concern in clinical practice due to limited treatments. This study aimed to explore the pharmacological effects and regulatory mechanism of sappanone A (SA) on ALI. In vivo, mice were administered with SA followed by intratracheal injection of lipopolysaccharide (LPS) to establish an animal model of ALI.

Analysis of clinicopathological characteristics and prognostic factors in 54 metaplastic breast carcinoma patients from northwest China.

Objective: Metaplastic breast carcinoma (MBC) is a special type of morphologically heterogeneous and aggressively invasive breast cancer. MBC is characterized by the transformation of tumor epithelium into squamous epithelium and/or mesenchymal components, including differentiation into spindle cells, chondrocytes, and osteocytes. Due to its rarity and invasiveness, there is a paucity of research on MBC prognosis.

Exploring the influencing factors of non-insulin drug prescriptions in discharged patients with type 1 diabetes.

Objective: The aim of this study was to evaluate the admission indicators and characteristics of individuals diagnosed with type 1 diabetes (T1D) to ascertain potential impact on the choice of glucose control therapy after discharge.

Methods: A total of 398 eligible T1D patients were selected. We conducted multivariable logistic regression analysis to determine the independent influence of predictors on the selection of glucose control therapy after discharge.