Publications by authors named "Drozdova N"

The environmental pollution by toxic Co(II) ions had a negative impact on living organisms and water resources. The amorphous Zr-Ca-Mg and Ti-Ca-Mg phosphates with varied Zr and Ti content with the mesoporous structure (A = 19-232 m/g, V = 0.075-0.

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Background And Objectives: COVID-19 convalescent plasma is an experimental treatment against SARS-CoV-2. The aim of this study is to assess the impact of different pathogen reduction methods on the levels and virus neutralizing activity of the specific antibodies against SARS-CoV2 in convalescent plasma.

Materials And Methods: A total of 140 plasma doses collected by plasmapheresis from COVID-19 convalescent donors were subjected to pathogen reduction by three methods: methylene blue (M)/visible light, riboflavin (R)/UVB and amotosalen (A)/UVA.

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Article Synopsis
  • Scientists created a new score to check how serious infections in the tummy area are for patients.
  • They studied over 4,500 patients in many hospitals around the world to see what factors affect survival rates.
  • The new score is very accurate in predicting if a patient will survive or not, which can help doctors make better decisions.
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Dental procedures in mentally retarded children is challenging for both dentist and for anesthesiologist. The aim of the study was to evaluate the efficacy and safety of dental care procedures under general anesthesia with sevoflurane by means of laryngeal mask in mentally retarded children. The randomized controlled study included 65 mentally retarded children with ASA 2-3 who underwent dental treatment.

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Background: Serum procalcitonin (PCT) is considered to be a sensitive marker for the early recognition of severe infection. The aim of this study was to review the diagnostic accuracy of serum procalcitonin levels to predict the risk of septic shock and mortality in patients with secondary peritonitis.

Methods: We carried out a retrospective review of patients (November 2010 to November 2012) admitted to the surgical intensive care unit (ICU) with secondary peritonitis classified into localised peritonitis (LP) or diffuse peritonitis (DP) groups.

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Background: Restoration of gastrointestinal function is a crucial determinant of favorable outcome in severe acute pancreatitis (SAP). The purpose of this study was to retrospectively review our experience with early oral feeding in patients with the necrotizing form of SAP. Over the last 10 years, we have routinely gradually increased oral feeds in order to restore gastrointestinal function.

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Background: The control of sepsis is the primary goal of surgical intervention in patients with infected necrosis. Simple surgical approaches that are easy to reproduce may improve outcomes when specialists in endoscopy are not available. The aim of the present study was to describe the experience with a focused open necrosectomy (FON) in patients with infected necrosis.

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Background: Conservative treatment of patients with severe acute pancreatitis (SAP) may be associated with development of intra-abdominal hypertension (IAH), deterioration of visceral perfusion and increased risk of multiple organ dysfunction. Fluid balance is essential for maintenance of adequate organ perfusion and control of the third space. Timely application of continuous veno-venous haemofiltration (CVVH) may help in balancing fluid replacement and removal of cytokines from the blood and tissue compartments.

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Phagocytic activity of alveolar macrophages isolated from rat bronchoalveolar lavage fluid was studied during their reaction with multilamellar liposomes containing biene (a complex of unsaturated fatty acids). Liposomes with incorporated biene significantly stimulated phagocytic activity of freshly isolated macrophages and primary culture of these cells (judging from the increase in phagocytic index and phagocytic number). A quantitative relationship between the phagocytic number and phagocytic index, on the one hand, and the concentration of liposomal biene, on the other, was detected.

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The conditions of fatty acid complex "bien" incorporation into multilayered liposomes prepared by mechanical dispersion techniques (vortexing) have been investigated. Drug incorporation depends on the lipid composition used to prepare the vesicles, overall lipid and "bien" concentrations and the presence of an antioxidant. Vortexing and incubation regimes for the homogeneous liposomal suspension were determined.

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With the goal of mimicking the mechanisms of the biological effects of low energy laser irradiation, we have shown that infrared low intensity laser radiation causes oxygenation of the chemical traps of singlet oxygen dissolved in organic media and water saturated by air at normal atmospheric pressure. The photooxygenation rate was directly proportional to the oxygen concentration and strongly inhibited by the singlet oxygen quenchers. The maximum of the photooxygenation action spectrum coincided with the maximum of the oxygen absorption band at 1270 nm.

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Based upon bacteriological investigations the authors have proved bacteriostatic and sometimes bactericidal effects of the polymer material "Acryloxide". Endoprostheses made of it do not require sterilization which was demonstrated in operations of endoprosthesis of joints on 225 patients.

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In alcohol-glycerol solutions of bacteriopheophytin alpha takes place dimer formation with a long wave absorption band at 857 nm, the dimerization constant enhances with glycerol content increasing in solution. The measurement of absorption, fluorescence and CD spectra allowed to characterize the main electronic transitions (Qy, Qx, Bxy) of the dimer. For the first electronic transition (Qy) of the dimer as compared to the monomer the same oscillator strength, spectral bands narrowing of splitting components and significant increase of rotation strength in CD spectrum were found.

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Aggregation of bacteriopheophytins a and b (BPh) in ethanol--glycerol solution and a comparison of spectral properties of obtained aggregated pigment forms were studied. The dependence of aggregation process on percentage of glycerol and pigment concentration on alcohol solution was studied. The aggregation of BPh was followed by very strong deformation of electron absorption and circular dichroism (CD) spectra.

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