[Predictors of external pancreatic fistulae after pancreatic resection].

Despite a significant decrease in postoperative mortality after pancreatic resections in recent years (5.2-15% after pancreatoduodenectomy and about 5% after distal pancreatectomy), incidence of postoperative complications remains high (30-50% and 22-50%, respectively). Postoperative pancreatic fistula is one of the most common and formidable complications.

[Short- and long-term outcomes of laparoscopic interventions in patients with colon cancer: single-centre experience].

Objective: To compare short- and long-term outcomes of treatment in patients with colon cancer undergoing laparoscopic and open surgery.

Material And Methods: There were 281 patients with colon cancer. All patients underwent open (n=144, 51.

[The nature of changes in central hemodynamics and myocardial contractile capacity of the left ventricle during volumetric loading in patients with chronic alcoholism in relation to the duration of alcohol abuse].

Forty patients aged 33 to 66 years suffering from chronic alcoholism, stages II-III, were examined. All the patients were subjected to contrast ventriculography before and after exercise test to identify the latent forms of heart failure. According to the coronarography findings, 9 out of the 40 patients demonstrated the signs of atherosclerotic injury to the coronary arteries.

[Sensitivity of the lymphocyte chromosomes of chronic alcoholism patients to mutagenic exposure].

The level of chromosome aberrations induced by mitomycin C and cytosine arabinoside in the cultured lymphocytes from patients with chronic alcoholism is elevated, as compared to that observed in the cultured lymphocytes of healthy persons. A supposition was made that transitory instability of cell genome could cause this phenomenon.

[Distribution of acetylator phenotypes in the normal Moscow city population and in chronic alcoholism].

The distribution of acetylator phenotypes was studied in 169 normal individuals of Moscow Russian population and 75 inhabitants of Moscow suffering from chronic alcoholism. Polymorphism was found by means of acetylation in both groups studied. The proportion of repeatability of rapid and slow acetylators amounts to 48 and 52% among normal individuals, 44 and 56% among those who suffer from chronic alcoholism.

[Effect of tranquilizing agents on the blood level of endogenous ethanol in alcoholics].

Experiments on alcohol addicts blood were made to study the time course of the endogenous ethanol level after a single administration of mebicar (1.5 g), a derivative of bicyclic bisuria, 50 ml of 5% sodium hydroxybutyric syrup, a derivative of gamma-hydroxybutyric acid, and 20 mg diazepam, a derivative of 1,4-benzodiazepines. The clinical effect was recorded simultaneously.