Publications by authors named "Drosos G"

Unlabelled: The first Fragility Hip Fracture Registry has been established in Greece. The in-hospital length of stay was 10.8 days and was significantly influenced by the delayed surgical fixation.

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  • Imaging techniques, particularly ultrasound (US), have greatly enhanced physicians' ability to diagnose and differentiate conditions in pediatric orthopedic patients.
  • This review highlights US applications in trauma (like fractures), developmental disorders (e.g., hip dysplasia), soft tissue issues (such as cysts and tumors), and various musculoskeletal conditions.
  • US is an effective, low-cost, and non-invasive tool that, despite requiring expertise, provides safer procedures and is essential for orthopedic surgeons.
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The management of complex and severe lower-extremity injuries is challenging for the orthopedic surgeon. When the primary or secondary closure of the defect is not feasible, complex procedures with graft (split-thickness or full-thickness) or flap (pedicled or free) are required. These procedures are performed by specialized plastic surgeons and are at high risk for adverse effects, even high morbidity among both the donor and acceptor sites.

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  • Circulating cell-free DNA (ccfDNA) of mitochondrial origin (ccf-mtDNA) is a small part of the total ccfDNA in bodily fluids, with abnormal levels linked to various diseases.
  • A new standardized dual-qPCR assay effectively measures nuclear and mitochondrial ccfDNA, revealing that high ccf-mtDNA levels are significant in Breast Cancer and Type 2 Diabetes, but not in Osteoarthritis.
  • Machine learning was applied to create biosignatures for diagnosing and predicting outcomes in these diseases, highlighting their potential in improving clinical management.
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  • This study evaluated various cardiovascular risk prediction models to see how well they identify high-atherosclerotic cardiovascular risk (ASCVR) in patients with antiphospholipid syndrome (APS).
  • It used six first-CVD risk models and three recurrent-CVD models on 121 APS patients and assessed their accuracy using techniques like ultrasound to check for atherosclerotic plaques.
  • Results showed that while the models had moderate calibration, their ability to discriminate and classify patients was poor to acceptable, with significant numbers of patients being misclassified; ultrasound was particularly useful for reclassifying many patients at risk.
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Introduction: Fragility fractures around the proximal end of the femur have increased in recent years due to an aging population, adding to the pressure on national health care systems and to hospital expenses. Peri-trochanteric fractures have historically been treated successfully with anatomic intramedullary nails, giving stable fixation in order to allow early for mobilisation of these frail patients. Some of these nails allow a second (anti-rotational) screw through the nail into the femoral head.

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Plantar fasciitis is a common cause of heel pain. The aim of this study was to review the current literature and attempt to clarify whether endoscopic plantar fasciotomy (EPF) is an effective and reliable treatment for plantar fasciitis in comparison with other invasive or noninvasive treatments. We performed an electronic search of the medical literature in PubMed database using combinations of the following keywords: plantar fasciitis, endoscopic treatment, and plantar aponeurosis.

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Background: To examine blood pressure (BP) and lipid treatment eligibility in antiphospholipid syndrome (APS) according to European Alliance of Associations for Rheumatology (EULAR) and European Society of Cardiology (ESC) recommendations.

Methods: Systematic Coronary Risk Evaluation (SCORE), modified-SCORE, diabetes mellitus (DM)-equivalent risk classifiers (DIME) and disease-related classifiers -type of thrombotic events (APS), antiphospholipid-antibody profile (aPL) and adjusted Global APS Score for cardiovascular disease- were used to calculate predicted low-moderate, high and very-high cardiovascular risk (CVR) in 111 patients with APS without prior atherosclerotic cardiovascular events or DM. Actual CVR (AR) was determined according to ESC guidelines, including carotid/femoral plaque presence.

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The aim of this study was to report a rare case of a giant cell tumor of the patellar tendon sheath. This indicates the diagnostic procedures and treatment options for giant cell tumors of the patellar tendon. This study reported a case of a 13-year-old male patient with a giant cell tumor of the tendon sheath.

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  • The study investigates the effectiveness of both generic and disease-specific cardiovascular risk prediction tools for forecasting subclinical atherosclerosis progression in patients with Systemic Lupus Erythematosus (SLE), revealing that traditional tools may underestimate risk.
  • Among 124 SLE patients followed for about 40 months, 21% developed new atherosclerotic plaques, with the modified Framingham Risk Score (mFRS) and QRISK3 showing superior predictive abilities compared to other scores.
  • Multivariate analysis identified QRISK3 as a significant predictor of atherosclerosis progression along with factors like age, total glucocorticoid dose, and the presence of antiphospholipid antibodies.
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Background: The European Alliance of Associations for Rheumatology recommended that lipid-lowering therapy (LLT) in systemic lupus erythematosus (SLE) should follow general population guidelines. We examined the eligibility for LLT in SLE according to Systematic Coronary Risk Evaluation (SCORE), with and without the addition of vascular ultrasound (VUS) and disease-related features.

Methods: 210 patients with SLE without prior cardiovascular events, diabetes or antiphospholipid syndrome underwent cardiovascular risk assessment with SCORE.

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Unlabelled: Transient osteoporosis (TO) or bone marrow edema syndrome (BMES) is a self-limited clinical condition, which affects middle-aged men and women. It can be treated with miscellaneous conservative and surgical measures, which are analyzed in this systematic review.

Introduction: BMES/TO is a transient clinical entity, which can be treated with various therapeutic modalities.

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  • The study explores how body composition affects chronic low back pain, aiming to enhance understanding and treatment methods.
  • One hundred and twenty-one participants with chronic low back pain underwent questionnaires, biomedical exams, and bioimpedance analysis to assess body composition.
  • Results indicated that pain affects limb structure, leading to decreased balance and stability, and a tendency for fat accumulation and muscle loss in the affected leg, highlighting the need for further research on this multifaceted condition.
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The menisci are crescent-shaped, fibrocartilaginous structures that play a crucial role in the load transition and distribution of the contact forces along the tibiofemoral articulation. Meniscal extrusion (ME) is a radiological finding, especially in magnetic resonance imaging (MRI) scans, for which there has been growing interest in recent years. ME, in the coronary plane, is defined as the maximum distance of the most distal end of the meniscus from the border of the tibial plateau, where the tibial eminences are the most prominent, without taking into account the osteophytes.

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Background: The objective of our study was to compare a novel squared section, tapered design - with four conicity - short stem, the MINIMA® short stem with the cementless Profemur® TL standard femoral stem in primary total hip arthroplasty (THA) in terms of functional outcomes, radiologic evaluation and other peri-operative and post-operative data.

Material And Methods: This is a comparative study including 46 patients undergoing primary THA. In 23 patients, the MINIMA® short stem was used.

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Purpose: Several studies have shown that patients with severe osteoarthritis (OA) of the knee can reduce their knee pain, improve their quadriceps strength, and improve their functional ability through regular exercise training. The purpose of this study was to investigate the efficacy of a six-week supervised high-intensity preoperative training program on muscle strength, functional performance, and patient-reported outcomes in patients undergoing total knee arthroplasty (TKA).

Methods: Ninety-eight patients scheduled for unilateral TKA for severe OA were allocated to an intervention group (N = 49) who completed a six-week preoperative training program, five days per week prior to surgery, and a control group (N=49) who did not follow any preoperative training program.

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Inferior vena cava (IVC) thrombosis is often attributed to IVC filters. Here, we describe the first case of IVC filter thrombosis associated with severe acute respiratory syndrome coronavirus-2 infection in a 34-year-old male with multiple pelvic fractures. The IVC filter was initially placed prophylactically prior to major orthopedic trauma reconstruction complicated by silent pulmonary embolism, precluding the safe transition to therapeutic anticoagulation due to the high hemorrhagic risk from pelvic fracture fixation.

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Objective: To systematically review the scientific literature and to investigate the effectiveness of preoperative rehabilitation on subjective and objective outcomes after total knee arthroplasty (TKA) when compared with patients in a control group.

Data Sources: A search was conducted in PubMed, PubMed Central, Embase, Cochrane Library and Physiotherapy Evidence Database databases in May 2021.

Study Selection: randomized controlled trials (RCTs) were reviewed if they compared a preoperative physiotherapy exercise intervention with no intervention group for patients undergoing TKA for severe Osteoarthritis (OA).

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Objective: To develop recommendations for cardiovascular risk (CVR) management in gout, vasculitis, systemic sclerosis (SSc), myositis, mixed connective tissue disease (MCTD), Sjögren's syndrome (SS), systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS).

Methods: Following European League against Rheumatism (EULAR) standardised procedures, a multidisciplinary task force formulated recommendations for CVR prediction and management based on systematic literature reviews and expert opinion.

Results: Four overarching principles emphasising the need of regular screening and management of modifiable CVR factors and patient education were endorsed.

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A 74-year-old Caucasian woman presented with a large mass on her left distal radius, which had previously caused a fracture of the bone at this site and the palmar site that was treated with external fixation a year ago. The patient did not mention tumor-related family history and other neoplasms before the fracture of the distal radius. She noticed that the gradually growing mass had appeared after the fracture treatment.

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Reverse shoulder arthroplasty (RSA) has become an optimal treatment for numerous orthopedic entities, such as rotator cuff tear arthropathies, pseudoparalysis, fracture sequelae, acute fractures, failed arthroplasties, osteoarthritis, and rheumatoid arthritis, and is linked with relief of topical pain and regaining of functionality. Presently, RSA has been conducted through anterosuperior (AS) or deltopectoral (DP) approach. The aim of the study was to discuss both approaches and to examine broadly their features to render a comparison in terms of clinical effectiveness.

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Diabetic foot osteomyelitis (DFO) is a severe, difficult to treat infection. Local antibiotic delivery has been studied as a potential therapeutic adjunct following surgery for DFO. This review aims to summarize the evidence on local antibiotic delivery systems in DFO.

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