[The first isolation of Borrelia burgdorferi in Apodemus flavicollis in Yugoslavia].

Small rodent species, as well as their ectoparasitic fauna, and the presence of Borrelia burgdorferi in their blood and internal organs (liver and spleen) was investigated, at two locations (Kosutnjak, Lipovicka suma) in Belgrade. Animals were caught between September 15-17, 1992. On location Kosutnjak two Apodemus flavicollis were trapped and Borrelia burgdorferi was isolated from the spleen of one of them.

[Exposure to Ixodes ricinus bites among soldiers].

Results of an investigation on the exposure to tick bites among soldiers in 6 permanent army structures on the territory of Belgrade are shown. Four army structures were found to be active foci of Lyme borreliosis. Infection rates among Ixodes ticks were from 10% in urban structures to 42.

[A theoretical model for the study of Lyme borreliosis].

This article is a short review of: a) development of theory on natural foci of communicable diseases in man, b) methodological approach to the investigation of natural foci, e.g. theoretical model in their investigation, and c) the use of theoretical model in the investigation of Lyme borreliosis.

[Vectors of Borrelia burgdorferi].

During the period 1990-1992-5,915 ticks were collected and identified in the area of Belgrade. Identification has shown that 99.8% were Ixodes ricinus and 0.

[Ecology of Borrelia burgdorferi].

Much still remains to be understood about ecology of Borrelia burgdorferi which is transmitted by a number of ticks belonging primarily to the Ixodes complex, known to feed on different animal hosts and humans. This article pretends to be a review of previous knowledge of Borrelia burgdorferi ecology. Special emphasis is placed on the preliminary results of an investigation conducted in Yugoslavia on the risk of developing lyme borreliosis after a tick bite (Ixodes ricinus).

[Lyme disease in human medicine].

Six years of investigations of Lyme disease in our country has offered an opportunity for better understanding of this "new" illness, which is both a medical and a health problem. The number of patients with Lyme disease is found to be similar to the number of patients in other countries. Human infections occur in different areas, rural and urban settings.

[Modern immunologic tests in the diagnosis of Lyme borreliosis].

In this work we described the results that were obtained using various immunodiagnostic assays for the detection of lyme borreliosis. Sera of the patients that were in acute or chronical phase of the disease were analysed in indirect immunofluorescent, immunoenzyme and immunoblot assays which were prepared and carried out in our laboratory. As a control for the validity of these investigations, we used sera of the healthy people, as well as of the patients suffering of lues or rheumatoid illnesses.

[Lyme borreliosis in Belgrade].

In the period 1990-1992 in Belgrade area a diagnosis of Lyme disease was registered in 487 patients. There were 195 men and 292 women. The disease was registered in all ages groups, median age 38 y.

[Epidemiologic characteristics and serologic findings in erythema migrans].

Our three-year research covered 417 patients with erythema migrans, of both sexes and all age groups. Among them 87.3% had a history of tick bite.

[Epidemiology of Lyme borreliosis].

Our prospective study covered 1093 patients with epidemiological features and demonstrable clinical manifestations of Lyme borreliosis from 1987 to 1992. Basic criteria for the inclusion of our patients in the study were: tick bite, erythema migrans and antibodies to B. burgdorferi in each patient's serum.

[Epidemiologic characteristics of hemorrhagic fever with renal syndrome in a military population].

In the period 1952-1990 there have been recorded 84 patients with hemorrhagic fever with renal syndrome (HFRS): 81 soldiers and 3 officers of the Y.P.A.

Preventive medical protection in the Armed Forces of Yugoslavia during military conflicts.

Some experiences in preventive medical protection in the Armed Forces of the Yugoslav People's Army (Y.P.A.

[Ixodes ricinus proven as a vector of Lyme borreliosis in Yugoslavia].

263 fasting female Ixodes ricinus were examined for Borrelia burgorferi, the vector of Lyme borreliosis. Female ticks were collected by flagella in the biotopes (Belgrade and Osijek) in which ticks bite patients with Lyme borreliosis. Borrelia burgorferi was proved in 58 (22%) of 263 female ticks in the native preparations of the intestinal contents by darkfield microscopy.

[Surveillance methods in hospital infections].

In the prevalence study of postoperative pyogenic-inflammatory disease in 1,000 operated patients three parallel controls have been undertaken: comprehensive prospective control, current state and standard control. Current prevalence control has been proved the most suitable, practical and for hospital personnel the most acceptable control method.

[Lyme disease in Yugoslavia].

Presented are results of the last five-year period study of the lyme disease in Yugoslavia. On the basis of published papers and professional communications over 2500 cases of lyme disease.were detected in our country within this period.

[Hemorrhagic fever with renal syndrome in Yugoslavia 1951-1988].

Data on hemorrhagic fever with renal syndrome (HFRS) incidence in SFRY 1950-1988 were analysed. Information sources were published papers and official reports of Federal and Republic Institutions for Public Health. Indirect immunofluorescence technique was used in testing 1.