Publications by authors named "Drighil A"

This study introduces an innovative approach by employing a highly sensitive synchronous detection-based dynamic Sénarmont method for the precise measurement of electro-optical (EO) Pockels and Kerr coefficients within hybrid nanocomposite films. The experimental setup integrates LabVIEW instrumentation software, ensuring accurate data acquisition. The EO-active film compositions encompass diverse polymer (PMMA) and organic dye combinations, including PMMA/organic dyes (DR1 and CPO), as well as PMMA combined with DR1-SiC, DR1-TiO2, and CPO-TiO2.

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  • - Holt-Oram syndrome is a rare genetic disorder linked to mutations in the TBX5 gene, characterized by skeletal and heart abnormalities, particularly affecting cardiac prognosis.
  • - A case study of a 49-year-old patient revealed signs of congestive heart failure along with physical malformations like thumb triphalangia and scoliosis, leading to the discovery of an atrial septal defect through testing.
  • - Diagnosis involves genetic testing for TBX5 mutations, and family screening is important due to its autosomal dominant inheritance pattern, emphasizing the need for awareness of upper limb anomalies associated with heart issues.
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Introduction: Hydatidosis, caused by the Echinococcus tapeworm, typically manifests with hepatic and pulmonary symptoms, but cardiac involvement, especially in pediatric cases, poses a rare challenge. This overview emphasizes the diagnostic complexities and potential complications associated with this uncommon parasitic disease.

Case Presentation: A 4-year-old child was presented with epigastric pain after an abdominal impact trauma.

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  • * The clinical examination revealed the presence of Café-au-lait spots, which are common in NF1 patients, and imaging confirmed tumors on both adrenal glands.
  • * After confirming the diagnosis through urinary Vanillylmandelic acid (VMA) measurement, the woman underwent tumor removal, leading to successful blood pressure normalization and underscoring the need for screening in similar cases.
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  • * A case study details a young patient with heart issues identified as restrictive heart disease alongside primary amenorrhea, leading to her Kallmann syndrome diagnosis.
  • * The rare combination of cardiac problems in this syndrome suggests there might be an underlying genetic link that warrants further investigation.
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Background: Ankylosing spondylitis (AS) is a type of chronic inflammation that is most prevalent in young adults and is characterized by an inflammatory enthesiopathy that gradually develops toward ossification and ankylosis. If inflammation is left unchecked, it can potentially lead to complications such as secondary amyloidosis, also known as AA amyloidosis, involving the deposition of amyloid serum A protein. Our case presents with a thyroid localization of AA amyloidosis which is secondary to this AS.

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  • Infectious endocarditis is a serious condition linked to high mortality, involving complications like cardiac embolism and multisystem effects.
  • An 81-year-old patient faced severe complications, including brain abscesses and strokes due to septic emboli, diagnosed with infective endocarditis affecting his mitral valve.
  • The case highlights the importance of quick medical and surgical response from a specialized heart team, leading to a surprisingly positive outcome despite the usual grim expectations of such scenarios.
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Systemic lupus erythematosus (SLE or lupus) is a disease in which the immune system attacks healthy cells and tissues throughout the body. Lupus myocarditis is a life-threatening condition, observed clinically in 3-9 % of patients with SLE. We report the case of a patient followed for multisystem SLE, presenting with de novo heart failure with severe left ventricular dysfunction revealing lupus myocarditis.

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Atrial myxoma is a rare and benign clinical entity. It remains common in women and mainly affects the left atrium. Its clinical picture is polymorphic.

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Unlabelled: Interrupted aortic arch (IAA) is a rare congenital heart condition where there is a complete discontinuation between the ascending and descending aorta. The association with a patent ductus arteriosus or developed arterial collateral allows survival until adulthood in extremely rare cases. We report a case series of adult forms of IAA.

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Shone syndrome is a rare and complex congenital heart disease. It is characterized in its complete form, by a constellation of the four potentially obstructive lesions of the left heart side. Incomplete Shone's complex includes 2 or 3 of the characteristic lesions which, include a supravalvular mitral membrane, valvular mitral stenosis (MS) by a parachute mitral valve (PMV), subaortic stenosis and aortic coarctation (Coa).

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Background: Cerebral cardiac embolism accounts for an increasing proportion of ischemic strokes and transient ischemic attacks. Calcified cerebral emboli are rare and mostly iatrogenic secondary to heart or aorta catheterization. However, spontaneous cerebral calcified embolism in the case of calcified aortic valve is very rare and there are less than 10 case reports in the literature.

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  • Coronary artery ectasia is a rare condition observed in 0.3% to 5% of patients undergoing coronary angiography and is associated with increased risks after myocardial infarction treatments.* -
  • A case study details a 50-year-old male who experienced a heart complication, leading to the discovery of non-obstructive giant ectatic coronary arteries following treatment for ST-elevation myocardial infarction.* -
  • The patient was discharged with heart failure treatment and antiplatelet therapy after no underlying cause for the ectasia was found, highlighting the potential dangers of this condition during severe cardiovascular events.*
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Unlabelled: Laubry-Pezzi syndrome is a rare congenital heart disease characterized by the association of ventricular defect septal to aortic cusp prolapse responsible for aortic regurgitation (AR).

Case Presentation: We reported three cases of Laubry-Pezzi syndrome diagnosed in our department of cardiology on a cohort of more than 3000 cases of congenital heart disease. A 13-year-old patient presented a Laubry-Pezzi syndrome with severe AR and significant volumetric left ventricle overload and was operated on in time to allow a good evolution of his condition.

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  • - The study investigates the relationship between intima-media thickness (IMT) and cardiovascular events, utilizing vascular Doppler ultrasonography as a diagnostic tool.
  • - Conducted over six months with 102 patients, results revealed that 89.2% had elevated IMT (≥ 0.8 mm), with diabetes and hypertension being significant risk factors linked to this increase.
  • - The findings suggest that heightened IMT is a crucial indicator of cardiovascular risk, advocating for its routine assessment in future research.
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Background: Behçet's disease BD is a rare multisystemic disease, with rare cardiac involvement. This case illustrates a rare cardiac involvement as a giant intracavitary thrombus which was the revealing form of Behçet disease.

Case Presentation: An 15-year-old male admitted to the emergency department for progressive dyspnoea, hemoptysis for which an echocardiogram displayed a large echogenic mass in the right ventricle and angio CT revealed associated bilateral pulmonary embolism.

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Introduction: and importance: Leuconostoc is a genus of gram-positive bacteria, this type of bacteria, which can be found in green vegetables and are used in wine, cheese, and sugar production, is an uncommon cause of disease in human beings.

Case Report: We report the case of a 60 years old male, with a medical history of nasopharyngeal carcinoma treated by chemotherapy and radiotherapy. The patient was admitted for total hematuria and episodic fever for the last 2 months.

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Background: Systemic juvenile lupus erythematosus can affect any organ including the heart. While pericarditis and endocarditis are the most common cardiac complications, dilated cardiomyopathy remains rare. We report the full recovery of dilated cardiomyopathy in a girl with juvenile lupus.

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  • Endogenous endophthalmitis is a rare and serious infection often linked to infective endocarditis, primarily caused by coagulase-negative staphylococcus, especially in patients with prosthetic heart valves.
  • A case of a 70-year-old female with chronic renal failure on dialysis presented with endogenous endophthalmitis; tests revealed the presence of coagulase-negative staphylococcus and vegetation in the heart, leading to IV antibiotics and poor ocular prognosis.
  • The condition emphasizes the need for urgent diagnosis and treatment of underlying infections, particularly endocarditis, as early intervention is crucial for improving patient outcomes.
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  • - Infective endocarditis is a rare but serious condition mainly affecting older adults with various risk factors, and it can lead to serious complications.
  • - A case study describes a 52-year-old patient with end-stage renal failure who developed acute endocarditis complicated by acute cholecystitis, and after 6 weeks of early antibiotic treatment and supportive care, the patient's condition improved.
  • - The combination of infective endocarditis and acute cholecystitis presents a challenging prognosis, especially in patients with weakened immune systems like those in end-stage renal failure, emphasizing the need for prompt and effective treatment.
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  • Myeloproliferative neoplasms (MPNs) like polycythemia Vera (PV) and Essential Thrombocythemia (ET) can lead to serious blood clotting issues, including both venous and arterial thrombosis, but cases of both types occurring together have not been documented in young adults without a history of MPNs.
  • A case study is presented of a 39-year-old man without cardiovascular risk factors who experienced chest pain and severe headache, resulting in the discovery of heart attack, subarachnoid hemorrhage, and a unique blood clot condition, all associated with PV.
  • The findings highlight the potential for MPNs to cause dangerous clot-related problems in younger individuals, undersc
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Hemolytic uremic syndrome (HUS) is a non-exceptional, progressive complication of acute gastroenteritis in children, especially secondary to infection. It is responsible for significant morbidity and significant mortality (10% of deaths) because of acute renal failure which often complicates it. Dilated cardiomyopathy is a rare but critical extra renal manifestation of the HUS.

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Intra-alveolar bleeding is a rare and severe medical emergency due to numerous causes. We report the clinical case of a patient who could contribute to extend the literature on this subject. The study included a 62-year old man, with a history of a trial fibrillation, under anti-vitamins K antagonist admitted with dyspnoea of sudden onset associated with haemoptysis and practising self-medication using non-steroidal anti-inflammatory drugs.

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  • A rare case of a 3-year-old boy with right ventricular outflow tract obstruction caused by a subpulmonic membrane was presented, highlighting the unusual association with cor triatriatum dexter.
  • The boy experienced dyspnea and had significant pressure gradients across the membranes, which were partially relieved through balloon valvuloplasty, improving his exercise tolerance.
  • While balloon dilation showed promising results, surgery for resection of the membranes was planned but ultimately not conducted due to the patient's death from unrelated complications.
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Background: Carcinoid heart disease is a frequent complication of carcinoid syndrome. It is related to the release by the carcinoid tumor and/or its metastases of bioactive substances such as serotonin. It is characterized by right-sided valvular involvement and can lead to right-sided heart failure.

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