Publications by authors named "Dragoslava Marjanovic"

Purpose: To analyze the dose distribution achieved during 2D radiography-based brachytherapy (BRT) planning, by using a 3D MRI-based BRT replanning evaluation, in patients with advanced cervical carcinoma, treated with definitive concomitant chemoradiation (CCRT).

Methods: The curative CCRT was applied to 30 patients with advanced cervical carcinoma. For each patient, 2D radiography-based planning and a 3D MRI-based BRT replanning were performed.

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Purpose: The toxicity of postoperative radiotherapy for cervical cancer affects patients' quality of life. We evaluated acute toxicity in postoperative intensity-modulated radiotherapy (IMRT) and three-dimensional conformal radiotherapy (3DCRT) as well as the influence of dosimetric parameters and concomitant chemotherapy.

Methods: A total of 45 patients with early operable cervical cancer underwent postoperative IMRT with 40-45 Gy.

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Article Synopsis
  • - The study compared intensity-modulated radiotherapy (IMRT) to three-dimensional conformal radiotherapy (3DCRT) in the postoperative treatment of cervical cancer, focusing on dosimetric parameters for target volumes and organs at risk (OARs).
  • - After randomizing 95 cervical cancer patients into two treatment groups (IMRT and 3DCRT), results indicated that IMRT provided better conformity and dosimetric outcomes, especially in terms of protecting the bladder, rectum, and bowel from high doses of radiation.
  • - The conclusion is that IMRT offers better sparing of OARs while maintaining adequate coverage of target volumes, which could lead to improved quality of life for patients with cervical cancer who have
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