Publications by authors named "Dragos L"

Purpose: To investigate the current thoughts and perspectives on kidney stone analysis amongst urologists and urology residents worldwide.

Methods: In October 2022 an online survey supported by the EULIS was circulated amongst urologists and urology residents worldwide. The survey was based on the current EAU guidelines regarding stone analysis and its role in urolithiasis management.

View Article and Find Full Text PDF

Flexible and navigable suction ureteral access sheath (FANS) is a potential game changer in flexible ureteroscopy (FURS). The influence of sheath size on outcomes needs research. The primary aim was to analyze 30-day single stage stone free status (SFS), zero fragment rate (ZFR) and complications when using 10/12Fr sheaths vis a vis other sheath sizes.

View Article and Find Full Text PDF

Purpose: To assess the time taken by the single use 7.5Fr suction flexible ureteroscope to reduce pressure under 40 mm Hg and to characterize the behavior of stones, fragments and dust during suction activation.

Methods: An in vitro setting was developed for this experiment.

View Article and Find Full Text PDF

Background: Technology allows us to predict a histopathological diagnosis, but the high costs prevent the large-scale use of these possibilities. The current liberal indication for surgery in benign thyroid conditions led to a rising frequency of incidental thyroid carcinoma, especially low-risk papillary micro-carcinomas.

Methods: We selected a cohort of 148 patients with thyroid nodules by ultrasound characteristics and investigated them by fine needle aspiration cytology (FNAC)and prospective BRAF collection for 70 patients.

View Article and Find Full Text PDF
Article Synopsis
  • The study aims to gather laser lithotripsy settings from experts for different clinical situations and to identify ways to minimize complications.
  • A survey was conducted among laser specialists, revealing that the majority use Holmium-YAG lasers, with variations in settings for specific scenarios like middle-ureteral, pelvic, and lower pole stones.
  • Experts reported a general consensus on preferred techniques, with preventive measures like power limits and intermittent activation commonly employed to reduce thermal injury risks during procedures.
View Article and Find Full Text PDF

Purpose: To highlight and compare experts' laser settings during endoscopic laser treatment of upper tract urothelial carcinoma (UTUC), to identify measures to reduce complications, and to propose guidance for endourologists.

Methods: Following a focused literature search to identify relevant questions, a survey was sent to laser experts. We asked participants for typical settings during specific scenarios (ureteroscopy (URS), retrograde intrarenal surgery (RIRS), and percutaneous treatment).

View Article and Find Full Text PDF

To evaluate the general practice among urologists about the use of various radiological imaging and measurement tools, and to compare the different preferences in radiological evaluations between Turkish and European urologists. Our study was designed as a survey study. The survey comprised 22 questions which evaluated the epidemiological information, caseload of participants, general preferences of participants on CT image slice thickness, basic radiologic workup routines prior to surgery, use of special tools and measurements on CT.

View Article and Find Full Text PDF

Objectives: The lithotripsy efficiency (LE) in vitro study requires artificial or human stone samples (AS, HS). With the development of dusting lithotripsy, less ex vivo HS are available. We aimed to compare Thulium Fiber Laser (TFL) and Holmium:YAG (Ho:YAG)'s LE and define the most accurate LE parameter.

View Article and Find Full Text PDF
Article Synopsis
  • A standardized tool called the TULIP tool was developed to evaluate flexible ureterorenoscopes (fURS) through a consensus-building approach using the modified Delphi technique.
  • A systematic review identified relevant parameters, leading to six main categories and 12 subcategories for evaluation, with high consensus among a panel of 30 endourology experts.
  • The project reached a high agreement on both the definitions and measurement methods of these categories, setting the stage for more uniform comparisons in fURS research.
View Article and Find Full Text PDF

To assess the diagnostic accuracy and intra-observer agreement of endoscopic stone recognition (ESR) compared with formal stone analysis. Stone analysis is a corner stone in the prevention of stone recurrence. Although X-ray diffraction (XRD) and infrared spectroscopy are the recommended techniques for reliable formal stone analysis, this is not always possible, and the process takes time and is costly.

View Article and Find Full Text PDF

Blastic plasmacytoid dendritic cell neoplasms (BPDCNs) are extremely rare and aggressive hematological malignancies that derive from precursors of plasmacytoid dendritic cells (pDC) and frequently involve skin lesions and bone marrow infiltration. They mostly affect the elderly population and the prognosis is poor with the therapeutic choices currently available. Diagnosis is made with the help of tools such as immunohistochemistry and flow cytometry.

View Article and Find Full Text PDF

Kidney stone disease (KSD) is a complex disease. Besides the high risk of recurrence, its association with systemic disorders contributes to the burden of disease. Sufficient water intake is crucial for prevention of KSD, however, the mineral content of water might influence stone formation, bone health and cardiovascular (CVD) risk.

View Article and Find Full Text PDF

Purpose: PCNL requires a lithotrite to efficiently break stones, and some devices include active suction to remove the fragments. We set out to determine the efficacy and safety of the Swiss LithoClast® Trilogy, in a prospective European multicentre evaluation and compared it to published stone clearance rates for Trilogy based on surface area (68.9 mm/min) and using the 3D calculated stone volume (526.

View Article and Find Full Text PDF

Purpose: To evaluate the efficiency and efficacy of HoLEP, and methods of tissue retrieval, in patients with prostate volume (PV) ≥ 200 cc (Group 1) and to compare these to patients with PV 80-199 cc (Group 2).

Methods: A database of all cases performed under the care of two surgeons at a tertiary HoLEP centre was reviewed.

Results: 157 patients with PV ≥ 200 cc were compared to 157 of the most recent consecutive cases with PV 80-199 cc.

View Article and Find Full Text PDF

Multiple large bladder calculi are traditionally managed through open cystolithotomy or transurethrally in patients who have an open bladder neck. Open procedures are technically challenging in patients who may have had multiple previous open surgeries, and may be associated with significant morbidity in patients with a high comorbid burden. Therefore, a percutaneous approach to such stones has been used especially when there is a closed bladder neck, and has been shown to be effective.

View Article and Find Full Text PDF

Clinical data suggest an equipoise between single-use (disposable) and reusable flexible ureterorenoscope (fURS) in terms of scope characteristics, manipulation, view and clinical outcomes. The procedural cost of reusable fURS is dependent on the initial and repair cost, maintenance and scope sterilization and on the number of procedures performed/repair. We conducted a systematic review on the procedural cost ($) of fURS based on the individual authors reported data on the number of procedures performed before repair and to see if it is a feasible option compared to single use fURS.

View Article and Find Full Text PDF

With an increase in the number of ureteroscopy (URS) procedures, URS is now performed more widely and is becoming a standard procedure for all urologists. There is also a rise in the complexity of these procedures and URS is now offered for treatment of stones as well as for diagnosis and treatment of urothelial tumours. We wanted to provide a 'pictorial review' of the 'tips and tricks' of URS, as the finer and technical details are often easier to understand and remember with images rather than through textual explanations.

View Article and Find Full Text PDF

Background: Single-use flexible ureterorenoscopes (fURSs) have been recently introduced aiming to offer solutions to the sterilization, fragility and cost issues of the reusable fURSs. In order to be a viable alternative, the single-use scopes must prove similar capabilities when compared to their reusable counterparts. The goal of our study was to compare the current reusable and single-use digital fURSs regarding their deflection, irrigation and vision characteristics.

View Article and Find Full Text PDF

Introduction: Research for management of benign prostate obstruction (BPO) for adult males remains a cornerstone of urology research. This landscape has witnessed the rise and fall of multiple therapies, both surgical and medical. Our aim was to formally evaluate the publication trends for these interventions over the past 20 years.

View Article and Find Full Text PDF

The development of mutations in the BCR-ABL1 fusion gene transcript causes resistance to tyrosine kinase inhibitors (TKIs) based therapy in chronic myeloid leukemia (CML). Thereby, screening for BCR-ABL1 mutations is advised especially in patients undergoing poor response to treatment. In the current study the authors investigated 43 patients with CML that failed or had suboptimal response to TKIs treatment.

View Article and Find Full Text PDF

Purpose Of Review: Cystine stone patients can be difficult to manage with frequent recurrences. We performed a systematic review with a view to assessing interventions, compliance and their long-term outcomes.

Recent Findings: Ten retrospective observational studies (253 patients) assessed the outcomes and long-term follow-up of cystine stone patients.

View Article and Find Full Text PDF

Purpose: To evaluate how variable working distances between the laser fiber and the stone influence ablation volume.

Methods: A laser fiber was fixed on a robotic arm perpendicular to an artificial stone. A single laser pulse was triggered at different working distances (0-2.

View Article and Find Full Text PDF

Introduction: Since 2012 Elmed has been working on a robot specifically designed for flexible ureteroscopy. After the first version of Avicenna Roboflex, a second version was developed in 2015, with significant changes especially in the irrigation system. We consider mandatory for the endourologist that works with the Avicenna Roboflex be aware of the functioning of the irrigation system.

View Article and Find Full Text PDF
Article Synopsis
  • Flexible ureterorenoscopy (fURS) is effective for treating kidney stones under 2 cm and upper urinary tract cancers, but there's limited research on which fURS provides the best image quality.
  • A study compared seven types of fURS using videos rated by 103 participants, revealing that digital ureterorenoscopes generally outperformed fiber optic ones in image quality.
  • The Storz D ureterorenoscopes, especially in Clara Chroma mode, provided the best overall image quality, with Olympus V performing notably well, while Olympus P6 and Storz X2 had lower quality ratings.
View Article and Find Full Text PDF

Objective: Clinical presentation of ureteral stones during pregnancy is generally with renal colic pain. The aim of this study is to present our experience in the management of renal colic during pregnancy in emergency settings.

Materials And Methods: 208 pregnant patients who presented to emergency department with renal colic pain and underwent ureteroscopy (URS) due to failed conservative therapy were enrolled in the study.

View Article and Find Full Text PDF