Renal biopsy registry from a single centre in Serbia: 20 years of experience.

Background: There is not enough epidemiologic data of biopsy proven renal diseases. This is the first report of clinicopathologic correlations over a period of 20 years from central Balkan country-Serbia.

Methods: A retrospective review of reports of 2 362 native renal biopsies performed on patients at the leading nephrology unit in Serbia from 1987 to 2006 was undertaken.

[Comparison of various cyclophosphamide treatment regimens on the course and outcome of lupus nephritis ].

Introduction: Immunosuppressive drugs, particularly cyclophosphamide, are widely accepted as the treatment of choice for severe, proliferative lupus nephritis. However, there is no consensus with regard to: 1) the dose required for achieving control of disease activity; 2) duration of cyclophosphamide therapy after the achievement of treatment response; 3) treatment of lupus nephritis relapses [1-5]. In the Institute of Rheumatology, Belgrade, two regimens of intravenous cyclophosphamide have been introduced in the treatment of lupus nephritis patients years ago.

[Therapy of lupus nephritis with standard therapeutic protocols and cyclosporine].

The study carried out was at the Department of Nephrology, Military Medical Academy, over the period from 1996 to 2001. Different types of lupus nephritis were documented in 42 patients and were treated with standard therapeutic protocols (corticosteroids, the pulse dose of cyclophosphamide + corticosteroids) and cyclosporine in the target serum concentration of 100-120 ng/ml along with pronisone of 15-20 mg per day. The different degree of damaged renal function was observed.

[Analysis of living related kidney donors and their postoperative course].

Lack of cadaveric organs for transplantation resulted in increased number of living related kidney donors examinations and consequent transplantations in our Department. Donor procedure, selection, drop-outs and final results for living related donors (LRD) were retrospectively analyzed in this paper. Between 1987 and 1994 202 potential LRD were examined.