Early diagnosis of disseminated nocardiosis in a case of pyomyositis and brain abscesses exemplifies the importance of smear examination.

We report a 73-year-old immunocompromised man with multiple muscle abscesses, in a toxic state with neurological deficits, with a history of panhypopituitarism, diabetes, hypothyroidism, and recent SARS-CoV-2 infection. MRI showed abscesses in the right chest wall, right thigh (peri-implant), and left adductor. Elevated inflammatory markers, comorbidities and clinical presentation suggested disseminated fungal or Nocardial infection.