Publications by authors named "Downey R"

Objective: Evaluate an electronic platform for remote symptom monitoring to enhance postdischarge care in thoracic surgery using patient reporting of symptoms.

Summary Background Data: Owing to the increased use of enhanced recovery after surgery protocols, patients are spending a larger portion of their postoperative course at home. For patients undergoing complex operations, this represents an opportunity for early identification of abnormal symptoms at home before deterioration.

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Age-related hearing loss is a risk factor for mobility problems and falls, possibly due to poor access to spatial sounds or the higher allocation of attention required to listen, thereby reducing cognitive resources to support mobility. Introducing stabilizing spatial sounds or reducing cognitive load through hearing aids could possibly improve balance performance; however, evidence is mixed. Few studies have evaluated the effects of hearing aids and spatial sounds on balance during realistic, multisensory, dual-tasking conditions.

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  • The study aimed to create a prediction model to help decide between stereotactic body radiotherapy (SBRT) and minimally invasive surgery (MIS) for treating early-stage non-small cell lung cancer (NSCLC).
  • Researchers analyzed data from 1,291 patients to develop the model using logistic regression, which produced three risk categories for patient treatment based on several health factors.
  • The model showed strong predictive power and suggested that the decision on treatment modality does not significantly impact overall survival, highlighting the importance of assessing intermediate-risk patients through a multidisciplinary approach.
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  • The latest Commission on Cancer guidelines suggest specific lymph node sampling during lung cancer resections, but its effect on patient outcomes is not well-explored.
  • In a study of 9,289 lung resections, 33% followed the guidelines, showing higher rates of nodal upstaging and complications, yet similar rates of adjuvant therapy and recurrence.
  • While survival rates were similar in stages I and II, guideline adherence in stage III resulted in improved survival, indicating a need for further research on optimal lymph node sampling in diverse lung cancer cases.*
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  • The study examined the relationship between preoperative frailty and outcomes in older patients (65+) undergoing esophagectomy, rather than just focusing on age.
  • Using a frailty scoring system called MSK-FI, researchers analyzed 447 patients and found that higher frailty scores were linked to increased risks of major complications, readmissions, and being discharged to a facility after surgery.
  • Although frailty was a strong indicator of short-term morbidity, it did not correlate with 90-day mortality, suggesting it can help identify patients at higher risk for complications during surgery decision-making.
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  • Minimally invasive surgery (MIS) is becoming the standard for early-stage non-small cell lung cancer (NSCLC), but its effectiveness in more advanced stages (IB-IIIB) after neoadjuvant therapy is not well understood.
  • A study analyzed 627 patients from 2013-2022 who underwent surgery after neoadjuvant treatment, comparing outcomes between open surgery and MIS, with successful MIS defined by specific criteria.
  • Results showed a 77% success rate for MIS, with the clinical N stage being a key factor in determining success, while the T stage and type of neoadjuvant therapy did not significantly impact outcomes.
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Background: Surgical dogma suggests that enhanced recovery (ERAS) pathways are not feasible in the non-elective setting. This study challenges that dogma with the implementation of ERAS in non-elective colorectal surgery.

Methods: Single center review of all colorectal operations was performed following implementation of ERAS in non-elective colorectal surgery.

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In September 2022, CDC funded a nationwide program, Together TakeMeHome (TTMH), to expand distribution of HIV self-tests (HIVSTs) directly to consumers by mail through an online ordering portal. To publicize the availability of HIVSTs to priority audiences, particularly those disproportionately affected by HIV, CDC promoted this program through established partnerships and tailored resources from its Let's Stop HIV Together social marketing campaign. The online portal launched March 14, 2023, and through March 13, 2024, distributed 443,813 tests to 219,360 persons.

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Background: Results of recent clinical trials suggest that segmentectomy may be an acceptable alternative to lobectomy for selected patients with early-stage non-small cell lung cancer (NSCLC). Increased use of segmentectomy may result in a concomitant increase in occult node-positive (N+) disease on surgical pathology examination. The optimal management for such patients remains unknown.

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Introduction: Electronic nose (E-nose) technology has reported excellent sensitivity and specificity in the setting of lung cancer screening. However, the performance of E-nose specifically for early-stage tumors remains unclear. Therefore, the aim of our study was to assess the diagnostic performance of E-nose technology in clinical stage I lung cancer.

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Objective: To assess the performance of a lower predicted postoperative (ppo) forced expiratory volume in 1 second (FEV 1 ) or diffusion capacity of the lung for carbon monoxide (DLCO) (ppoFEV 1 /ppoDLCO) threshold to predict cardiopulmonary complications after minimally invasive surgery (MIS) lobectomy.

Background: Although MIS is associated with better postoperative outcomes than open surgery, MIS uses risk-assessment algorithms developed for open surgery. Moreover, several different definitions of cardiopulmonary complications are used for assessment.

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Background: Goals of care discussions are infrequently documented in the preoperative period. Furthermore, documentation does not consistently address what matters most to patients, although patient values (PV) are central to person-centered care.

Methods: A multidisciplinary working group was formed.

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Unlabelled: Mesopelagic fish (meso-fish) are central species within the Southern Ocean (SO). However, their ecosystem role and adaptive capacity to climate change are rarely integrated into protected areas assessments. This is a pity given their importance as crucial prey and predators in food webs, coupled with the impacts of climate change.

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Electrosurgery is commonly used during a range of operations in order to maintain effective haemostasis. This can cause electromagnetic interference (EMI) with cardiac implanted electronic devices (CIEDs), which prevents normal device function. CIEDs include pacemakers (PPM), implantable cardiac defibrillators (ICD), cardiac resynchronisation therapy devices-both pacemakers and defibrillators (CRT-P/CRT-D)-and implantable loop recorders (ILRs).

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Objective: To evaluate the perioperative as well as early oncological outcomes of patients undergoing robotic retroperitoneal lymph node dissection for treatment of testicular cancer.

Methods: We conducted a prospective consecutive case series of patients undergoing robotic assisted retroperitoneal lymph node dissection for metastatic testicular cancer between May 2018 and July 2021 at our institution. Data were collected on patient and tumour characteristics, intraoperative and postoperative parameters, and functional and oncological outcomes.

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Introduction: Patient falls in the hospital lead to adverse outcomes and impaired quality of life. Older adults with cancer who are frail may be at heightened risk of falls in the postoperative period. We sought to evaluate the association between degree of preoperative frailty and risk of inpatient postoperative falls and other outcomes among older adults with cancer.

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Article Synopsis
  • Hearing loss is linked to cognitive decline and increased risk of falls, as it requires extra cognitive resources for listening, potentially impacting other tasks.
  • The study aims to investigate if at-home cognitive training can enhance dual-task performance (doing two tasks simultaneously) in both normal-hearing adults and older adults who use hearing aids.
  • A randomized controlled trial will compare a 12-week executive function training program against a wait-list control, evaluating its effects on cognition, mobility, and hearing across different age groups.
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Objectives: The aim of this study was to compare postoperative outcomes between biologic and synthetic reconstructions after chest wall resection in a matched cohort.

Methods: All patients who underwent reconstruction after full-thickness chest wall resection from 2000 to 2022 were reviewed and stratified by prosthesis type (biologic or synthetic). Biologic prostheses were of biologic origin or were fully absorbable and incorporable.

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The goal of this study was to test a novel approach (iCanClean) to remove non-brain sources from scalp EEG data recorded in mobile conditions. We created an electrically conductive phantom head with 10 brain sources, 10 contaminating sources, scalp, and hair. We tested the ability of iCanClean to remove artifacts while preserving brain activity under six conditions: , , , , , and .

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Objective: Despite neoadjuvant chemoradiotherapy, Pancoast tumors still present surgical and oncologic challenges. To optimize outcomes, we used a multidisciplinary care paradigm with medical and radiation oncology, and involvement of spine neurosurgery for most T3 and all T4 tumors. Spine neurosurgery permitted resection of transverse process for T3 and vertebral body resection for T4 tumors.

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Mobile brain imaging with high-density electroencephalography (EEG) can provide insight into the cortical processes involved in complex human walking tasks. While uneven terrain is common in the natural environment and poses challenges to human balance control, there is limited understanding of the supraspinal processes involved with traversing uneven terrain. The primary objective of this study was to quantify electrocortical activity related to parametric variations in terrain unevenness for neurotypical young adults.

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