Publications by authors named "Douvali T"
Maculopapular Cutaneous Mastocytosis Successfully Treated with Omalizumab.
Acta Dermatovenerol Croat
April 2021
Dear Editor, Maculopapular cutaneous mastocytosis (MPCM), formerly telangiectasia macularis eruptiva perstans (TMEP), is an uncommon form of cutaneous mastocytosis first described on 1930 (1). It is more frequent in adults, and early diagnosis is crucial since it has been reported to be associated with serious underlying systemic disorders, such as myeloproliferative diseases and severe manifestations like anaphylaxis (2,3). Treatment of MPCM depends on the presence of systemic involvement and/or the clinical symptoms of the disease itself.
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- - Harlequin syndrome is a rare autonomic nervous system disorder that results in reduced facial flushing and sweating on one side, triggered by factors like exercise or stress.
- - The condition is linked to an issue in the cervical sympathetic nerves, specifically on the side that does not flush.
- - The text includes a case study of an 8-year-old with this syndrome and discusses other skin-related conditions that also use the term "harlequin."
Hidradenitis suppurativa and psoriasis are considered chronic inflammatory diseases suggesting the existence of common pathogenetic pathways. We present two cases of comorbid psoriasis and hidradenitis suppurativa, treated with certolizumab pegol and brodalumab due to failure of response to other conventional therapies. Monoclonal antibody therapies have revolutionized the treatment of chronic inflammatory disorders such as psoriasis and hidradenitis suppurativa.
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