Publications by authors named "Dourado J"

Background: We assessed association among household income, overall survival (OS), and cancer-specific survival (CSS) after proctectomy for rectal cancer.

Methods: Population-based cohort study included stage I-III rectal adenocarcinoma patients who underwent proctectomy (2010-2020), subdivided by household income at diagnosis [low (<$50,000), average ($50,000-74,999), above-average (≥$75,000)] and compared.

Results: Of 39,185 patients (59 ​% male; mean age 60.

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Pelvic exenteration (PE) entails an en bloc resection of locally advanced primary or recurrent rectal cancer. This study aimed to assess the short-term and survival outcomes of minimally invasive (MI)- and open PE. A retrospective cohort analysis of patients with stage III rectal adenocarcinoma treated with PE from the National Cancer Database (2010-2019) was conducted.

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Article Synopsis
  • Colorectal anastomotic devices have been used for almost 100 years, with stapled methods being most common, despite a significant leak risk of up to 20%.
  • A systematic review and meta-analysis explored newer anastomotic devices, analyzing 18 studies from the last decade, which included 955 anastomoses and focused on non-stapled methods.
  • The findings indicated a pooled complication rate of 9.7% for human studies, but new compression mechanisms showed a much lower leak rate of 3.3%, suggesting that these novel technologies could improve surgical outcomes.
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  • This systematic review evaluated how upper gastrointestinal (UGI) dysmotility affects outcomes in patients with colonic inertia (CI) undergoing surgery.
  • It found that patients with UGI dysmotility were more likely to experience recurrence of constipation after surgery and had poorer improvements in quality of life compared to those without UGI issues.
  • The review suggests routine evaluation of UGI function before surgery for CI, as many patients with UGI dysmotility may go undiagnosed.
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Background: Tumor deposits are a unique histologic feature of colorectal cancer that is associated with adverse survival outcomes. The present study aimed to assess the association between tumor deposits and liver and lung metastases and to describe the characteristics of colorectal cancer associated with tumor deposits.

Methods: The Surveillance, Epidemiology, End Results (SEER) database was screened between 2010 and 2020 for patients with colorectal adenocarcinoma who underwent radical resection with data on tumor deposits.

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Background: Esophageal cancer remains a significant global health challenge. Several treatment modalities were explored in randomized controlled trials (RCTs) in recent decades. This study evaluates the robustness of RCTs focusing on esophageal cancer treatment using the fragility index (FI) and reverse fragility index (RFI).

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Background: This study aimed to investigate factors associated with prolonged operative time in laparoscopic right hemicolectomy for colon cancer.

Methods: This was a retrospective review of patients with colon cancer who underwent laparoscopic right hemicolectomy between 2011 and 2021. Linear and binary logistic regression analyses were performed to determine factors associated with prolonged operative time.

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Background: The National Accreditation Program for Rectal Cancer (NAPRC) recommends definitive treatment of rectal cancer commence within 60 days from diagnosis. This study aimed to assess predictors of >60 days delay between diagnosis and definitive surgery of rectal cancer and the impact on survival and short-term outcomes.

Methods: Retrospective cohort analysis of patients with stage I-III rectal adenocarcinoma who underwent proctectomy without preoperative neoadjuvant treatment from the National Cancer Database (2015-2019).

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Background: This umbrella review aimed to summarize the findings and conclusions of published systematic reviews on the prophylactic role of mesh against parastomal hernias in colorectal surgery.

Methods: PRISMA-compliant umbrella overview of systematic reviews on the role of mesh in prevention of parastomal hernias was conducted. PubMed and Scopus were searched through November 2023.

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Article Synopsis
  • Surgical treatments for refractory gastroparesis, like gastric electrical stimulation (GES) and pyloromyotomy, were analyzed to see if they work better together.
  • A study at Cleveland Clinic Florida reviewed data from 134 patients over 20 years to compare outcomes for those who had GES with and without pyloromyotomy.
  • Results showed that while patients with pyloromyotomy had a higher success rate after 5 years (82% vs. 62%), the difference wasn’t statistically significant; however, diabetic patients seemed to benefit more from the combined treatment.
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Background: Thermal ablation has recently become a key therapy for the treatment of colorectal liver metastasis (CLM). However, the role of ablation in combination with resection has not yet been firmly established. We hypothesize that in patients with CLM, those who undergo liver resection with ablation (RA) have similar outcomes compared with those who undergo liver resection only.

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Background: Robotic surgery is becoming increasingly popular in bariatric-metabolic surgery. However, its superiority regarding postoperative outcomes compared with conventional laparoscopy has not been clearly proven. With growing adoption of robotic surgery and improved technologies, benefits should become more evident.

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Background: This study aimed to assess concordance between clinical and pathologic assessment of colon cancer.

Patients And Methods: A retrospective cohort analysis of patients with stage I-III colon cancer in the National Cancer Database (2010-2019) was conducted. Concordance between clinical and pathologic assessment of colon cancer was calculated using Kappa coefficients and 95% confidence intervals (CIs).

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Introduction: Bibliometrics, a statistical method assessing the influence of scholarly works, was employed to analyze the evolution of endoscopic surgery for craniosynostosis.

Methods: This comprehensive review followed PRISMA guidelines, sourcing data from PubMed, Embase, and Web of Science, focusing on clinical and surgical outcomes up to December 2023. We identified 1409 records, with 83 papers meeting inclusion criteria.

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Article Synopsis
  • A systematic review and meta-analysis evaluated the effectiveness and safety of low-pressure pneumoperitoneum (LPP) versus standard-pressure pneumoperitoneum (SPP) in minimally invasive colorectal surgery.
  • The analysis focused on various outcomes such as postoperative pain, operative time, hospital stay, blood loss, and complications, using data from four studies with 537 patients.
  • Results indicated that LPP resulted in significantly lower pain scores in the post-anesthesia care unit and the first postoperative day, with similar operative times and safety profiles compared to SPP, though certain patient demographics might be at higher risk for complications.
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Background: Available platforms for local excision (LE) of early rectal cancer are rigid or flexible [trans‑anal minimally invasive surgery (TAMIS)]. We systematically searched the literature to compare outcomes between platforms.

Methods: PRISMA-compliant search of PubMed and Scopus databases until September 2022 was undertaken in this random-effect meta-analysis.

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Background: Ureteric injury (UI) is an infrequent but serious complication of colorectal surgery. Prophylactic ureteric stenting is employed to avoid UI, yet its efficacy remains debated. Intraoperative indocyanine green fluorescence imaging (ICG-FI) has been used to facilitate ureter detection.

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Background And Objectives: Chronic subdural hematoma (CSDH) management involves various surgical techniques, with drainage systems playing a pivotal role. While passive drainage (PD) and active drainage (AD) are both used, their efficacy remains contentious. Some studies favor PD for lower recurrence rates, while others suggest AD superiority.

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