Publications by authors named "Douglas Smoot"

Article Synopsis
  • Scientists found that adding special bone marrow cells can help skin transplants last longer in mice.
  • They tested different types of bone marrow to see which ones worked best for the skin grafts.
  • The best results came from using a specific group of cells that are only a small part of the total bone marrow, meaning those cells are really important for keeping the skin grafts healthy for a longer time.
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Erythrocytic cycle malaria parasite growth or invasion inhibition assays (GIA) compare the effects of various test and control substances on malaria parasite growth in erythrocytes or invasion into erythrocytes in vitro. Although inhibitions by antimalarial drugs in vitro correlate well with drug protective levels required in vivo, as yet there are too few data to know how well inhibitions by antibodies in vitro correlate with the types and degrees of immune protection in vivo. Antibody-mediated GIA is frequently complicated by parasite strain-specific inhibitions, as well as nonspecific inhibitory factors generated in sera collected or stored under nonoptimal conditions.

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