Publications by authors named "Douglas Rabin"
Article Synopsis
- The study focused on a new non-invasive prenatal screening (NIPS) test for detecting fetal aneuploidies using advanced sequencing techniques and automated processes.
- Validation of the test involved thousands of maternal plasma samples, leading to effective discrimination between affected (autosomal trisomy) and unaffected pregnancies.
- Positive predictive values (PPVs) were significantly high, at 98% for trisomy 21, 92% for trisomy 18, and 69% for trisomy 13, with improvements noted after addressing false-positive causes.
Background: In the United States, human papillomavirus (HPV) and Papanicolaou (Pap) testing (cotesting) for cervical screening in women ages 30 to 65 years is the preferred strategy, and cytology alone is acceptable. Recently, a proprietary automated test for identifying high-risk HPV types for primary cervical screening was approved by the US Food and Drug Administration. The objective of the current study was to document extensive cervical screening among these screening options.
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