Publications by authors named "Douglas Leonard"

Background: Sleep and circadian rhythms are markedly altered in intensive care unit (ICU) patients. Numerous factors related to the patient and the ICU environment affect the ability to initiate and maintain sleep. Therefore, nonpharmacological interventions could play an essential role in improving sleep and circadian rhythm.

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Introduction: In critically ill patients, sleep and circadian rhythms are greatly altered. These disturbances have been associated with adverse consequences, including increased mortality. Factors associated with the ICU environment, such as exposure to inadequate light and noise levels during the day and night or inflexible schedules of daily care activities, have been described as playing an essential role in sleep disturbances.

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The DAMA/LIBRA collaboration has reported the observation of an annual modulation in the event rate that has been attributed to dark matter interactions over the last two decades. However, even though tremendous efforts to detect similar dark matter interactions were pursued, no definitive evidence has been observed to corroborate the DAMA/LIBRA signal. Many studies assuming various dark matter models have attempted to reconcile DAMA/LIBRA's modulation signals and null results from other experiments, however no clear conclusion can be drawn.

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AMoRE (Advanced Mo-based Rare process Experiment) is an international collaboration searching for the neutrinoless double-beta decay of the Mo isotope with cryogenic detectors using molybdate (MoO)-based scintillation crystals. The process requires that the detector apparatus and its components, including bolometric crystals and thus initial materials used for the crystal growth, be extremely low in radioactive isotopes having decays that may generate background noise signals in the region of interest. The present study summarizes an ICP-MS assay program conducted for the AMoRE experiment.

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We present new constraints on dark matter interactions using 1.7 years of COSINE-100 data. The COSINE-100 experiment, consisting of 106 kg of tallium-doped sodium iodide [NaI(Tl)] target material, is aimed to test DAMA’s claim of dark matter observation using the same NaI(Tl) detectors.

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Objectives: Staff working in mental health services provide care for individuals with a variety of difficulties, which can pose treatment challenges. Perceived lack of progress in patients can engender uncomfortable feelings within the clinician, such as frustration, 'heartsink' and 'feeling stuck'. The aim of this study was to explore the phenomenon of 'feeling stuck' amongst NCHDs in psychiatry.

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Aims And Method: To apply process mapping, a component of lean management, to a liaison psychiatry service of an emergency department. Lean management is a strategy that has been adapted to healthcare from business and production industries and aims to improve efficiency of a process. The process consisted of four stages: individual interviews with stakeholders, generation of process maps, allocation of goals and assessment of outcomes.

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A large percentage of patients subjected to general anesthesia at 65 years and older exhibit postoperative delirium (POD). Here, we test the hypothesis that inhaled anesthetics (IAs), such as Sevoflurane and Isoflurane, act directly on brain vascular endothelial cells (BVECs) to increase blood-brain barrier (BBB) permeability, thereby contributing to POD. Rats of young (3-5 months), middle (10-12 months) and old (17-19 months) ages were anesthetized with Sevoflurane or Isoflurane for 3h.

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Introduction: As the rate of obesity and bariatric surgery rise, various psychosocial etiologies contributing to obesity are being explored, and it is not uncommon to discover that a patient has been a victim of past abuse.

Presentation Of Case: A 37-year-old female was hospitalized for intractable nausea and vomiting following a laparoscopic Roux-en-Y gastric bypass performed a month and a half prior. After ruling out all medical etiologies, psychiatry was consulted due to a history of panic attacks, and to evaluate for a psychosomatic etiology.

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Depression will be the second leading contributor to the global burden of disease by 2020. In Ireland, in 2009, 6061 people were hospitalised with depressive disorders. This represents a significant economic and social burden.

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Analyses of supernovae (SNe) have revealed two main types of progenitors: exploding white dwarfs and collapsing massive stars. Here we describe SN 2002bj, which stands out as different from any SN reported to date. Its light curve rose and declined very rapidly, yet reached a peak intrinsic brightness greater than -18 magnitude.

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Human lives depend on the performance of our trainees; thus, the educational methodology used to transform our learners into experts are of paramount importance. Effective use of simulation requires educators explore and apply educational theory as they discover who the learner is, how the learner learns, what the learning needs are, and which planned learning experiences are best suited to meet the learner's specialized needs. The purpose of this article is to portray simulation as an educational strategy in the context of a curriculum, to explore emerging theories from educational psychology, and to provide concrete examples of their application in simulation-based education.

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A new method for constructing laboratory-scale porous media with increased pore-level variabilities for two-phase flow experiments is presented here. These devices have been created with stereolithography directly on glass, thus improving the stability of the model created with this precision rapid construction technique. The method of construction and improved parameters are discussed in detail, followed by a brief comparison of two-phase drainage results for air invasion into the water-saturated porous medium.

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An important and perhaps critical clue to the mechanism driving the explosion of massive stars as supernovae is provided by the accumulating evidence for asymmetry in the explosion. Indirect evidence comes from high pulsar velocities, associations of supernovae with long-soft gamma-ray bursts, and asymmetries in late-time emission-line profiles. Spectropolarimetry provides a direct probe of young supernova geometry, with higher polarization generally indicating a greater departure from spherical symmetry.

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