An experimental investigation into the impact of acute stress on alcohol craving.

Drinking to cope is associated with many negative alcohol-related outcomes among college students, such as increased alcohol use, drinking-related problems, and alcohol use disorders. Previous experimental studies have shown that students exposed to a stressor, compared to those not exposed to a stressor, drink more and have stronger urges to drink, presumably to cope with the stressor. However, no such study has tested this effect using a remote-based stressor, which may be more common for students because of the recent increase in online learning.

An Application of the Stressor-Vulnerability Model of Drinking in College Student Drinkers.

The stressor vulnerability model provides theoretical support for conditions under which drinking to cope (DTC) is likely to occur (i.e., decreased adaptive coping, increased positive alcohol expectancies).

Simultaneous Substance Use With Alcohol in a Community-Based Sample of Young Adults.

Simultaneous substance use is associated with worse outcomes than concurrent use. Further investigations into simultaneous use are warranted because there is limited knowledge about the co-use of substances other than alcohol and cannabis. Study aims were to examine: (1) the prevalence of simultaneous use of substances with alcohol, (2) the extent to which use patterns are related to key correlates (i.

The impact of the COVID-19 pandemic experiences on college drinking via mental distress: Cross-sectional mediation moderated by race.

Background: The COVID-19 pandemic has been linked to stress, anxiety, and depression among college students, with heightened distress tied to greater drinking for some individuals. Emerging research suggests that these associations may differ across race, but few studies use adequate samples to examine this, particularly among college students, an at-risk population for both heavy drinking and mental distress. Specifically, pandemic-related stressors and mental distress may be higher among Black students than White students.

Differential Pathways of Risky Drinking via Coping Motives in College and Noncollege Young Adults.

The current study tested a mediation model of psychological functioning (i.e., perceived stressors, psychological distress, and self-regulation) and risky drinking through a drinking to cope pathway comparing college and noncollege young adults.

Social network moderators of brief alcohol intervention impact.

Objective: This investigation examined the impact of social networks on drinking reduction efforts following a brief alcohol intervention. In a reanalysis of data from an earlier randomized controlled trial with nonstudent emerging adult drinkers (Lau-Barraco et al., 2018), we aimed to test three domains of preintervention social network features as potential factors influencing intervention response: (a) general network characteristics (i.

Minority stress and alcohol use in sexual minority women's daily lives.

Sexual minority women (i.e., women who identify as lesbian, bisexual, or other non-heterosexual orientations) report more hazardous drinking compared to heterosexual women.

Idiopathic Adulthood Ductopenia Causing Cirrhosis.

Idiopathic adulthood ductopenia (IAD) is a chronic small duct cholestatic biliary disease that is characterized by the loss of interlobular bile ducts. It is diagnosed when there is biochemical evidence of cholestatic liver disease, ductopenia on liver biopsy, and no other identifiable cause of cholestasis. We present a patient with 10 days of progressive abdominal pain, jaundice, and worsening liver function tests who advanced to fulminant liver failure with no apparent underlying cause.

Adolescent methylmercury exposure alters short-term remembering, but not sustained attention, in male Long-Evans rats.

Methylmercury is an environmental neurotoxicant found in fish that produces behavioral deficits following early developmental exposure. The impact of adolescent exposure to this developmental neurotoxicant is only recently being explored in animal models. Here, short-term memory and sustained attention were examined using a rodent model of adolescent methylmercury exposure.

Angiotensin-converting enzyme (insertion/deletion) and endothelial nitric oxide synthase polymorphisms in patients with systemic lupus erythematosus.

Objective: Genetic polymorphisms in the angiotensin-converting enzyme (ACE) and endothelial nitric oxide synthase (eNOS) are linked with expression and/or progression of renal disease. We hypothesized that polymorphisms in the genes coding for ACE and eNOS may influence the development and/or progression of systemic lupus erythematosus (SLE) and lupus nephritis given their linkage with other renal diseases.

Methods: DNA from patients with SLE (n = 227) and their age and sex matched controls (n = 275) from the Carolina Lupus (CLU) Study cohort was assessed for ACE and eNOS polymorphisms.

Nodular scleroderma: case report and literature review.

Objective: To describe a unique case of scleroderma (SSc) presenting as multiple keloidal nodules and early-onset osteoarthritis (OA), and to summarize the clinical and serological data for 13 similar patients reported in the English literature since 1966.

Methods: MEDLINE review of the literature over a 35-year period (1966-2002) revealed 13 cases of nodular SSc. We describe a case of nodular SSc in a 40-year-old African-American male with localized SSc who developed progressive skin thickening and keloidal nodules on the arms, hands, chest, abdomen, and thighs with advanced osteoarthritis of the hips.

Wegener's granulomatosis in patients with rheumatoid arthritis.

Objective: To describe 2 cases of coexisting rheumatoid arthritis (RA) and Wegener's granulomatosis (WG), and to summarize the clinical and serological data for all 6 patients reported in the English literature since 1966.

Methods: Medline review over a 35-year period (1966-2002) revealed 4 reported cases of RA associated with WG. Patients were diagnosed based on symptoms, radiographic changes, bronchoalveolar lavage fluid analysis, hematuria, serology, and biopsy.