Publications by authors named "Douglas Alexandre do Espirito Santo"
Comparison between ultrasonography and computed tomography for measuring skeletal muscle mass in critically ill patients with different body mass index.
Clin Nutr ESPEN
February 2024
Article Synopsis
- The study aimed to evaluate the effectiveness of ultrasonography compared to computed tomography (CT) in measuring quadriceps muscle mass in critically ill patients with varying body mass indices (BMI) following traumatic brain injuries.
- Conducted in a specialized trauma ICU, the research involved a sequential analysis of muscle thickness using both ultrasound and CT scans at three different time points during patient admission.
- The results showed that while there were minor differences between the two measurement methods, these discrepancies were clinically insignificant, indicating a strong correlation between ultrasonography and CT regardless of the patients' BMI.
Introduction: Coronavirus disease 2019 (COVID-19) causes a hypercoagulable state. Several autopsy studies have found microthrombi in pulmonary circulation.
Methods: In this randomized, open-label, phase II study, we randomized COVID-19 patients requiring mechanical ventilation to receive either therapeutic enoxaparin or the standard anticoagulant thromboprophylaxis.
Several autopsy studies showed microthrombi in pulmonary circulation of severe COVID-19 patients. The major limitation of these investigations is that the autopsy provided static information. Some of these alterations could be secondary to the disseminated intravascular coagulation (DIC) observed as the final standard route to the multisystem organ failure exhibited in critically ill patients.
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