Publications by authors named "Douglas A Velasquez"
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Synopsis of recent research by authors named "Douglas A Velasquez"
- Douglas A. Velasquez's research predominantly focuses on the neurobiological mechanisms regulating appetite and energy metabolism, emphasizing the role of hypothalamic pathways and various neuropeptides such as ghrelin and melanin-concentrating hormone (MCH).
- His studies have revealed that hypothalamic κ-opioid receptors and the central Sirtuin 1/p53 pathway are critical in mediating the orexigenic effects of ghrelin, while MCH influences liver and adipose tissue metabolism through specific neuronal circuits.
- Velasquez also explores the endocannabinoid system's involvement in energy balance, illustrating its regulatory effects on glucose and energy metabolism across various tissues, further contributing to the understanding of metabolic disorders.
