Publications by authors named "Doug Adams"
Aim: These studies were to validate the analytical performance of a gene expression signature that differentiates melanoma and nevi, using RNA expression from 14 signature genes and nine normalization genes that generates a melanoma diagnostic score (MDS).
Materials & Methods: Formalin-fixed paraffin-embedded melanocytic lesions were evaluated in these studies.
Results: The overall SD of the assay was determined to be 0.
Objective: Exposure to altitude may lead to acute mountain sickness (AMS) in nonacclimatized individuals. We surveyed AMS prevalence and potential risk factors in trekkers crossing a 5400-m pass in Nepal and compared the results with those of 2 similar studies conducted 12 and 24 years earlier.
Methods: In April 2010, 500 surveys were distributed to English-speaking trekkers at 3500 m on their way to 5400 m, of which 332 (66%) surveys were returned complete.
Performance tests on lutetium oxyorthosilicate (LSO)-based PET scanners cannot be conducted strictly according to the National Electrical Manufacturers Association (NEMA) NU 2 standards because of the presence of intrinsic radioactivity within the LSO crystal scintillator material. This background radiation gives rise mainly to random coincidence events but also to a small number of true coincidences, which cannot be eliminated from measurements on such scanners and must therefore be corrected for in the data analysis. The current NU 2 standards do not take account of these backgrounds and hence can lead to erroneous results on LSO-based machines.
View Article and Find Full Text PDFBackground: Ruptures of the patellar tendon are rare injuries. Surgical treatment for this injury is mandatory.
Hypothesis: Gap formation does not differ between the three patellar tendon repair techniques.