Testicular Incidentaloma on F-choline PET/CT in a Patient with Prostatic Adenocarcinoma.

Prostatic adenocarcinoma is characterized by elevated phosphatidylcholine metabolism. F-choline positron emission tomography/computed tomography (PET/CT) is widely used for patients with biochemical recurrence and a prostate-specific antigen threshold above 2 ng/mL. We report a case of a patient with high-risk prostatic adenocarcinoma undergoing F-choline PET/CT for biochemical recurrence.

COVID-19 pneumonia incidentally discovered on [18F]F-PSMA-1007 PET/CT scan.

A 75-year-old man underwent a positron emission tomography/computed tomography (PET/CT) scan with fluorine-18-prostate specific membrane antigen ([¹⁸F]F-PSMA-1007) for initial staging of prostate adenocarcinoma. The scan showed lung infiltrates predominantly in both lower lobes with moderate uptake, in addition to a bilateral pulmonary hilar lymph node uptake. CT images revealed ground-glass opacities and a reticular pattern, suggesting COVID-19 pneumonia, which was confirmed by reverse transcription polymerase chain reaction (RT-PCR).

Incidental Tc-99m MIBI Lung Uptake in Parathyroid Scintigraphy.

Diffuse Tc-99m MIBI uptake in the lungs during parathyroid scintigraphy is exceptional, and only a few cases have described this unusual aspect. The differential diagnostic of this funding is a challenge when interpreting the examination, since it can be a sign of serious pathology. We report the case of unexpected diffusely increased Tc-99m MIBI uptake in bilateral lung fields in a patient with left cardiac dysfunction.

Development and validation of a Medaka fish voxel-based model for internal ionizing radiation dosimetry.

In this paper, we present a voxel-based phantom of Medaka fish that can be used to assess the internal radiation doses that would be absorbed by different organs of this fish species if exposed to radioactive wastewater released into the ocean. The geometric model for fish was generated based on available Wavefront Object files for smooth-bodied Medaka fish organs, whereas due to the lack of Medaka fish material specification, the material model was constructed using material data appropriate to ICRP 110 adult male voxel-based phantom. Absorbed Fractions (AFs) and Specific Absorbed Fractions (SAFs) were calculated for eight organs of major interest as sources and for each organ as target at a set of discrete photon, electron, alpha and neutron energies.

Comparison between InterDosi and MCNP in the estimation of photon SAFs on a series of ICRP pediatric voxelized phantoms.

In the present work, a new Monte Carlo Geant4 based code called InterDosi 1.0, was used to simulate specific absorbed fractions (SAFs) in the six reference pediatric voxel-based phantoms developed by the International Commission on Radiological Protection (ICRP). The aim of this study was to assess the ability of this code to estimate SAFs in a variety of voxel-based phantoms.

Validation of the DoseCalcs Monte Carlo code for estimating the F S-values for ICRP adult and 15-year-old male and female phantoms.

Internal radiation exposure using radiopharmaceuticals, as in nuclear medicine procedures, necessitates the estimation of the S-value to determine and improve the estimates of absorbed doses in at-risk organs and tissues. The S value is defined as the absorbed dose in the target organ per unit of nuclear transformation in the source organ. It is calculated using the specific absorbed fraction, which is an important quantity that connects the deposited energy in the target and emitting source organs.

Determining Local Magnetic Susceptibility Tensors in Paramagnetic Lanthanide Crystalline Powders from Solid-State NMR Chemical Shift Anisotropies.

Exploring magnetic properties at the molecular level is a challenge that has been met by developing many experimental and theoretical solutions, such as polarized neutron diffraction (PND), muon-spin rotation (μ-SR), electron paramagnetic resonance (EPR), SQUID-based magnetometry measurements, and advanced modeling on open-shell systems and relativistic calculations. These methods are powerful tools that shed light on the local magnetic response in specifically designed magnetic materials such as contrast agents, for MRI, molecular magnets, magnetic tags for biological NMR, etc. All of these methods have their advantages and disadvantages.

Neurolymphomatosis diagnosed on [18F]FDG PET/CT.

Fluorine-18-deoxyglucose positron emission tomography/computed tomography ([18F]FDG PET/CT) has been shown to be superior to other conventional imaging modalities in the detection of extra-nodal lymphomatous localizations. Especially in neurolymphomatosis which is rarely encountered in high-grade lymphomas. We report a case of a woman diagnosed with non-Hodgkin lymphoma, whose initial staging with [18F]FDG PET/CT showed increased [18F]FDG uptake along the brachial and sacral plexuses.

Intercomparison of S-Factor values calculated in Zubal voxelized phantom for eleven radionuclides commonly used in targeted prostate cancer therapy.

In this study we aimed at comparing various radionuclides ordinarily used in targeted prostate cancer therapy, thereby evaluating S-Factor parameter in the prostate organs as well as in its surrounding healthy tissues, namely the urinary bladder and rectum. InterDosi code version 1.1 was used to estimate S-Factor values in Zubal voxelized phantom for 11 radionuclides, namely Ac, At, Cu, I, I, Pb, Lu, Ra,  Tb, Th and Y.

COVID-19 Pneumonia was Incidentally Detected on F-Fluorocholine PET/CT in a Work-up for Prostate Cancer.

This is a presentation of the case of a patient who underwent F-fluorocholine positron emission/computed tomography to stage a prostate cancer with incidentally found bilateral pneumonia. A high prevalence of incidental pneumonia is very probable under the current circumstance of coronavirus disease-2019 (COVID-19) pandemic, and oncological patients are at increased risk of COVID-19 with poorer outcome. The lung inflammatory burden in the case of COVID-19 infection can be demonstrated by F-fluorocholine.

InterDosi Monte Carlo study of radiation exposure of a reference crab phantom due to radioactive wastewater deposited in marine environment following the Fukushima nuclear accident.

S-values are typically used to quantify internal doses of biota internally due to the incorporation of radionuclides. In this study, the InterDosi 1.0 Monte Carlo code was used to estimate S-values in five main organs of a crab phantom as well as in surrounding seawater for eleven radionuclides, namely H, C, Cs, Cs, Co, Sb, Sr, I, Tc, Ru, and Pu.

Bleomycin-Induced Lung Toxicity in Hodgkin's Lymphoma: Risk Factors in the Positron Emission Tomography Era.

Introduction Bleomycin is a major antimitotic agent in the first-line treatment for Hodgkin's lymphoma. The main limitation of its use is its pulmonary toxicity. The objectives of this study are to find out the risk factors for the occurrence of bleomycin-induced lung toxicity in patients with Hodgkin's lymphoma and, on the other hand, to determine if positron emission tomography scan is a reliable means of early detection of this toxicity.

Estimation of electron-specific absorbed fractions with the InterDosi code using ICRP adult female voxel-based phantom.

The International Commission on Radiological Protection (ICRP) through its publications recommends the estimation of Specific Absorbed Fractions (SAFs) using voxelized phantoms in order to assess the doses internally absorbed by organs exposed to ionizing radiation. In the present work, we report a large set of SAFs calculated using the ICRP Adult Female (ICRP-AF) phantom. The new Geant4-based code called InterDosi version 1.

InterDosi Monte Carlo simulations of photon and electron specific absorbed fractions in a voxel-based crab phantom.

InterDosi is a new in-house Monte Carlo code that aims at facilitating the use of the Geant4 toolkit for internal dosimetry using voxel-based phantoms. In the present work the dosimetric capabilities of this code are assessed by calculating self-irradiation specific absorbed fractions (SI-SAFs) in a voxel-based crab phantom. Recent standard human organ compositions and densities taken from ICRP Publication 110 have been used for material specifications of the four organs of a crab, namely, the heart, hepatopancreas, gills, and gonads, whereas the material assigned to the crab shell has been modeled based on literature values.

A rare case of pituitary metastasis from breast cancer detected on fluorodeoxyglucose positron emission tomography/computed tomography that presented as insipid diabetes.

Pituitary metastases are rare, are generally asymptomatic, and often remain undiagnosed. Breast cancer is the most common primary cancer metastasizing to hypophysis in women. However, it is difficult to clinically and radiologically differentiate pituitary metastases from pituitary adenomas.

Bilateral renal involvement in diffuse large B-cell lymphoma on fluorodeoxyglucose positron emission tomography/computed tomography.

Secondary renal involvement in patients with diffuse large B-cell lymphoma (DLBCL) is rare and associated with poor prognosis. We, hereby, described a case of a patient diagnosed with DLBCL, in whom bilateral renal involvement was detected on 18F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT). The patient received 4 courses of chemotherapy, and follow-up F-FDG PET/ CT revealed the complete resolution of the diffuse increased renal F-FDG uptake.

InterDosi simulations of photon and alpha specific absorbed fractions in zubal voxelized phantom.

In this work we used the InterDosi code to estimate photon specific absorbed fractions (SAFs) for some organs of the Zubal adult male voxelized phantom. Chemical compositions and densities of ICRP 110 adult male organs were attributed to those of the studied voxelized phantom. The SAFs of monoenergetic photons with energies ranging from 0.

Unsuspected Intramedullary Spinal Cord Metastasis Detected by FDG PET/CT.

Intramedullary spinal cord metastases (SCMs) are extremely rare. Here, we report a case of a 60-year-old man with a history of right nonsmall cell lung cancer treated by concomitant radiochemotherapy who complained, 9 months after treatment completion, of chest pain, breath shortness, and more recently back pain. An F-FDG PET/CT was performed as part of the restaging process and showed a hypermetabolic mass of the right lung in addition to ipsilateral mediastinal hypermetabolic lymph nodes.

Detection of muscle metastases on F-fluorodeoxyglucose positron emission tomography/computed tomography scan in 13 cases.

Muscular metastases (MMs) form an infrequent entity, and their physiopathology is still not well-defined. In this study, we estimated the incidence of MMs that were detected by F-fluorodeoxyglucose positron emission tomography/computed tomography and also specified their metabolic characteristics. This study includes 13 patients with MMs from a remotely located primary tumor.

Ratios of internal doses deposited in different organs to the whole body when such organ is adopted as source of F-fluorodeoxyglucose, a Monte Carlo Geant4 study on a male medical internal radiation dose phantom.

In the present study, the last stable version of Monte Carlo Geant4 code known as Geant4.10.3 has been used for measuring internal dose ratios to the whole body for about 40 organs.

Towards Iron(II) Complexes with Octahedral Geometry: Synthesis, Structure and Photophysical Properties.

The control of ligand-field splitting in iron (II) complexes is critical to slow down the metal-to-ligand charge transfer (MLCT)-excited states deactivation pathways. The gap between the metal-centered states is maximal when the coordination sphere of the complex approaches an ideal octahedral geometry. Two new iron(II) complexes ( and ) prepared from pyridylNHC and pyridylquinoline type ligands, respectively, have a near-perfect octahedral coordination of the metal.

Contribution of radiobiphosphonates bone scan in multifocal tuberculous osteomyelitis.

We share the case of a 86-year-old male patient, followed up for recent left hip pain. Interrogation revealed a fever, nocturnal shivering, and bone pains. Standard radiographs and computed tomography centered on both shoulders and pelvis showed osteoarthritis of the left hip and multiple lytic lesions in both humeral heads and clavicles, suggestive of chronic infectious, metabolic, or secondary disease.