Publications by authors named "Doshi D"

Introduction: The super high-pressure NC balloon (OPN NC; SIS Medical AG, Winterthur, Switzerland) is increasingly used in percutaneous coronary intervention (PCI). We performed a systematic review and meta-analysis of its efficacy and safety.

Methods: A systematic review was conducted using PubMed and the Cochrane Library to identify studies using the OPN NC balloon in PCI.

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Coronary artery disease (CAD) is the leading cause of mortality among patients with chronic kidney disease (CKD), presenting unique challenges in diagnosis and management. Advanced CKD patients often present with atypical symptoms, and conventional diagnostic and interventional approaches carry risks, including contrast-induced nephropathy and the potential need for renal replacement therapy. These risks have led to the phenomenon of "renalism," where necessary procedures may be deferred due to concerns over renal injury.

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Background: Lorry drivers work tirelessly behind the wheels, commuting from one place to another without regular and adequate food, rest and sleep. These people often have odd working hours, long work shifts with frequent changes to their work schedule. In addition, they work in unfavorable climate conditions and face variety of problems like traffic congestions, vehicle fumes, vibrations and poor conditions of roads.

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Rationale: Early mortality in intracerebral hemorrhage (ICH) is due to hematoma volume (HV) expansion, and there are no effective treatments available other than reduction in blood pressure. Tranexamic acid (TXA) a hemostatic drug that is widely available and safe can be a cost-effective treatment for ICH, if proven efficacious.

Hypothesis: Administration of TXA in ICH patients when given within 4.

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Introduction: Only a finite number of standard oral health-related quality of life (OHRQoL) measures are available for young children. However, instead of using parents as proxies to report a child's oral health status, children's self-reported oral health measures would be more accurate in providing their own perceptions of oral impacts.

Aim: The study aimed to evaluate the psychometric properties of the Telugu version of the scale of oral health outcomes (SOHO-5T) for 5-year-old children in Telangana.

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Torsemide, a loop diuretic, is increasingly recognized for its role in managing essential hypertension. Its mechanism of action involves inhibiting the reabsorption of sodium and chloride ions in the ascending loop of Henle in the kidneys. By doing so, torsemide promotes diuresis, which refers to increased urine production, and subsequently lowers blood pressure.

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Context: Dental bleaching, a common cosmetic treatment, typically uses hydrogen peroxide (HO). Yet, the search for natural options has prompted an investigation into fruit extract efficacies such as papain, bromelain, and actinidin for tooth whitening.

Aim: The aim of this study was to evaluate the efficacy of 30% hydrogen peroxide and fruit extracts (papaya, pineapple, and kiwi) on human enamel using a spectrophotometer at different time intervals.

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Aim: This study aimed to develop and validate an instrument, Dental Visiting Behavior Based on Health Belief Model among Adults (DVBHBM), and to assess factors influencing adults' dental visiting behavior based on Health Belief Model.

Materials And Methods: This cross-sectional study was conducted among 277 adults in Hyderabad, India. The DVBHBM instrument, based on Health Belief Model, was developed, validated, and distributed among participants.

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Background: Intravascular lithotripsy (IVL) safely and effectively modifies calcified coronary lesions during percutaneous coronary interventions (PCI). Data regarding its utility in modifying calcified left main coronary artery (LMCA) disease are limited. This study aimed to evaluate short-term outcomes of IVL-assisted LMCA PCI.

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The prevalence of calcification in obstructive coronary artery disease is on the rise. Percutaneous coronary intervention of these calcified lesions is associated with increased short-term and long-term risks. To optimize percutaneous coronary intervention results, there is an expanding array of treatment modalities geared toward calcium modification prior to stent implantation.

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Background: Acidic beverages are believed to elevate the risk of enamel surface erosion. In addition to the intake of soft drinks, the increased consumption of salad dressings has been linked to a higher prevalence of dental erosion. Therefore, the current study aimed to investigate the influence of bottled salad dressings on the development of enamel erosion in the presence or absence of pellicle through in vitro experiment.

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Background: Reducing falls and fractures remains an important clinical goal in managing older residents with Parkinson's disease psychosis (PDP) in long-term care/nursing home (LTC/NH) settings.

Objectives: This analysis examined risk of all-cause falls or fractures among PDP residents on continuous monotherapy with pimavanserin (PIM) versus (i) other atypical antipsychotics (AAPs) [quetiapine (QUE), risperidone (RIS), olanzapine (OLA), aripiprazole (ARI)] and (ii) QUE.

Methods: A retrospective analysis of parts A, B, and D claims from a 100% Medicare sample (2013-2019) in LTC/NH settings was conducted.

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Article Synopsis
  • The literature review discusses how AI predictive analytics can significantly improve patient outcomes by predicting disease progression, optimizing treatment, and enhancing recovery rates.
  • AI's capabilities, especially through machine learning and deep learning, enable personalized medicine by analyzing large datasets for early detection and tailored treatment strategies.
  • The review highlights the importance of addressing ethical issues like data privacy and bias while emphasizing the need for ongoing validation of AI models to ensure they safely complement human medical judgment.
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Real-world healthcare resource use (HCRU) burden among patients with Parkinson's disease psychosis (PDP) treated with pimavanserin (PIM) versus other atypical antipsychotics (other-AAPs) including quetiapine (QUE) in long term care (LTC) and nursing home (NH) settings are lacking. This analysis examines HCRU differences among residents in LTC/NH settings who initiate PIM versus QUE or other-AAPs. A retrospective analysis of LTC/NH residents with PDP from the 100% Medicare claims between 1 April 2015 and 31 December 2021 was conducted.

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Introduction: Obesity disproportionately affects some non-White and low-socioeconomic-status Americans. Medical obesity treatment includes aggressive lifestyle interventions with medications when applicable. We evaluated a physician-led, resource-limited obesity medicine program.

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Background: Patients with Parkinson's disease psychosis (PDP) treated with pimavanserin (PIM) versus other atypical antipsychotics (AAPs) including quetiapine (QUE) may have health-care cost savings due to fewer skilled nursing facility-stays (SNF-stays) and long-term care admissions (LTCA).

Methods: A decision analytic model was developed using the 2019 Medicare Patient Driven Payment Model (PDPM) to estimate SNF-stays and LTCA associated per-patient- per-year (PPPY) facility and rehabilitation costs among patients that initiated PIM vs QUE or vs other-AAPs (i.e, quetiapine, risperidone, olanzapine, aripiprazole).

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Risk of long-term care (LTC) admission (LTCA) associated with atypical antipsychotic (AAP) use among patients with Parkinson's disease psychosis (PDP) is a major concern. However, no comparative studies have examined the differences in risk of LTC admissions between pimavanserin (PIM), the only FDA-approved AAP for PDP, and other off-label AAPs including quetiapine (QUE). To examine all-cause LTCA rates and risk among PDP patients treated with AAPs such as QUE or PIM.

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Background: Real-world evidence examining the incremental health care resource use (HCRU) and cost burden of incident dementia among patients with Parkinson's disease psychosis (PDP) are needed within the United States (US).

Objectives: To compare HCRU and cost burden between PDP patients with incident dementia (PDP + D) versus without incident dementia (PDP).

Methods: A retrospective analysis of inpatient (Part A), outpatient (Part B), and prescription drug (Part D) claims from the 100% Medicare sample was conducted to compare PDP + D patients versus PDP patients between 01/01/14-12/31/18.

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Background: Physical disability results in impaired mobility, leading to increased dependency on others and may also have a negative impact on ones general and oral health. Moreover, such individuals could be at a greater risk of being prone to chronic pain conditions. A person's ability to cope with pain is a consistent and one of the most important predictors of clinical outcome.

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Purpose: This study aimed to examine personal and professional factors in determining the research activity and research culture among dental teaching faculty members in Hyderabad City, Telangana.

Materials And Method: Two dental schools with ongoing dental undergraduate and postgraduate programmes were included in the study. The Research and Development (R&D) Culture Index Questionnaire comprising 16 items was employed for this study.

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Background: Periodontal disease and chronic obstructive pulmonary disease (COPD) share a pathogenic mechanism that involves activating and using inflammatory cytokines and neutrophils, which generate pathological changes in various tissues with a chronic degenerative outcome.

Aim: the aim of this study was to assess and compare the periodontal health status among COPD patients with age- and gender-matched controls.

Materials And Methods: All the patients aged >30 years who were diagnosed with COPD by the physician were included as cases, while people who are apparently healthy and age and gender matched with cases were included as controls.

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Introduction: Weight bias is pervasive in health care and can lead to inadequate care for people with higher weight. However, few medical schools offer training on mitigating weight bias and incorporating body diversity into clinical care.

Methods: As part of a course for second-year medical students, we developed and implemented a 3-hour multimodal educational session on mitigating weight bias.

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Background: Yogurt, due to its rich casein phosphopeptide (CPP) content could promote remineralization of enamel. Contrary to the age-old usage of animal milk based yogurt, vegan dairy products are gaining momentum due to multiple reasons. Considering this change, the aim of the present study was to assess the in vitro effect of animal and plant-based yogurt extracts on demineralization of enamel.

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Background: Self-esteem is a psychological construct that has been consistently linked to general and oral health. However, most studies interpolating self-esteem and oral health behaviour have been focused on children and adolescents, and there is a dearth of scientific literature on adults. Hence, this study, that is aimed to correlate self-esteem with oral hygiene behaviour and oral health status in Telugu-speaking adult dental patients.

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