Clay-reinforced PVC composites and nanocomposites.

Clay-reinforced polyvinyl chloride (PVC) composites and nanocomposites are one of the newest and most important compounds studied and used in various applications, including the biomedical, automotive industry, water treatment, packaging, fire retarding, and construction. The most important clays used in the synthesis of these composites are Bentonite, Montmorillonite, Kaolinite, and Illite. The addition of these nanoclays to the PVC matrix improves mechanical properties, thermal stability, and yellowness index properties.

Spray freeze drying to solidify Nanosuspension of Cefixime into inhalable microparticles.

Purpose: Spray-freeze drying (SFD) incorporating diverse carbohydrates and leucine was employed to obtain dried nanosuspension of cefixime with improved dissolution profile, good dispersibility, and excellent inhalation performance.

Methods: Nanoprecipitation was utilized to prepare nanoparticles (NPs). Nanosuspensions of cefixime were solidified via SFD to access inhalable microparticles.

New analytical methods using carbon-based nanomaterials for detection of Salmonella species as a major food poisoning organism in water and soil resources.

Salmonella is one of the most prevalent causing agents of food- and water-borne illnesses, posing an ongoing public health threat. These food-poisoning bacteria contaminate the resources at different stages such as production, aggregation, processing, distribution, as well as marketing. According to the high incidence of salmonellosis, effective strategies for early-stage detection are required at the highest priority.

Design and Synthesis of Selective Acetylcholinesterase Inhibitors: Arylisoxazole-Phenylpiperazine Derivatives.

In this work, a novel series of arylisoxazole-phenylpiperazines were designed, synthesized, and evaluated toward acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Our results revealed that [5-(2-chlorophenyl)-1,2-oxazol-3-yl](4-phenylpiperazin-1-yl)methanone (5c) was the most potent AChE inhibitor with IC of 21.85 μm.