Background: Treatment options for pre-treated patients with metastatic triple-negative breast cancer (mTNBC) remain limited. This is the first study to assess the real-world safety and efficacy of sacituzumab govitecan (SG) in the UK.
Methods: Data was retrospectively collected from 16 tertiary UK cancer centres.
Background: Keratinocyte cancers (KCs) are the most common type of cancer in the White population worldwide, with associated high healthcare costs. Understanding the epidemiological trends for KCs, namely basal cell carcinomas (BCCs) and cutaneous squamous cell carcinomas (SCCs), is required to assess burden of disease, project future trends and identify strategies for addressing this pressing global health issue.
Objectives: To report trends in BCC and SCC incidence, and SCC mortality and disability-adjusted life-years (DALYs).
Florid cemento-osseous dysplasia, a benign fibro-osseous condition, is diagnosed based on characteristic radiographic appearances of multifocal round or lobulated sclerotic lesions associated with the teeth in multiple quadrants of the jaws. We report a case of a 73-year-old woman who presented with a painless sharp bony area on the right side of her maxilla. SPECT/CT of facial bones demonstrated multifocal intense increased uptake in both the maxilla and mandible, corresponding to ill-defined florid sclerotic periapical lesions seen on CT, in keeping with a classical appearance of florid cemento-osseous dysplasia.
View Article and Find Full Text PDFObjective: Physical activity after cancer is associated with a lower rate of adverse effects and better survival. The objectives of this study were to assess the exercise levels of people living with and beyond cancer attending a local oncology unit, and explore their attitudes to supervised exercise referral.
Methods: 134 patients attending the oncology unit over a 2 month period were approached to complete a questionnaire about their exercise levels and barriers to exercise.