Patients With Severe Alcohol-Related Cognitive Impairment Improve in Flexibility When Abstinence Is Maintained: A Comparative Study With Alzheimer's Disease.

The disease progression of severe alcohol-related cognitive impairment (ARCI) is debated. The aim of this study was to compare the cognitive change of patients with severe ARCI in inpatient setting to that of patients with Alzheimer's disease (AD). Fifteen consecutive patients with severe ARCI were recruited between 2013 and 2015.

[Screening, referring and counseling of adolescents for substance abuse. A randomized controlled study on 2120 students].

Objectives: The DEP-ADO assessment questionnaire defines three alcohol- and drug-related risk levels: low (green light), intermediate (yellow light) and high risk (red light). Our study sought to evaluate whether a DEP-ADO systematic screening by school nurses and physicians improves referring to specialized addiction consultations.

Method: Randomized controlled study with allocation of subjects by matched pairs of school classes: 1045 adolescents received a group information; 1075 adolescents were met individually and filled in the questionnaire; then either they received a risk reduction oriented intervention (yellow light) or were referred to an addiction outpatient clinic (red light).