Dermatologic therapy in geriatric patients.

Demographic changes in our society will lead to an increasing proportion of elderly people. Age-associated multimorbidity often results in polypharmacy and elevates the risk of adverse drug reactions. Decisive alterations in pharmacokinetics and pharmacodynamics are detectable in old age, primarily a decrease in total body water, an altered ratio of muscle mass to fatty tissue, and decreased renal function.

Facial pyoderma gangrenosum in senescence.

Clinically, pyoderma gangrenosum (PG) is characterized by a rapidly progressive, painful cutaneous ulcer with an irregular, violaceous and undermined border. PG occurs most frequently on the lower extremities and the trunk of middle-aged individuals. The face is only very rarely affected.

Seminal plasma adipokine levels are correlated with functional characteristics of spermatozoa.

Objective: To study adipokines as a potential link between obesity and male subfertility.

Design: Cross-sectional study of subjects stratified into subgroups according to body mass index (BMI): normal-weight (18.50-24.